iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Atr-003103

Ensembl Protein ID

ERM96204

UniProt Accession

W1NLS7; W1NLS7_AMBTC

Genbank Protein ID

ERM96204.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

KI397142

Gene Name

AMTR_s00001p00114780

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AMTR_s00001p00114780	ERM96204	ERM96204

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.00e-24	83.8	271	303
E3 adaptor/Cullin RING/APC_C/CDC20	2.40e-130	434.7	136	436

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           H+ +v++l++   ++ l+sG++D+ +++WD r+
   Q: 271  HEQEVCGLKWslCGKQLASGGNDNLLYIWDSRS 303
           99********965599**************876 PP

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 2    ekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkkvrtltghsarvga 101
           e+ ldap++ +d+ylnLldWs++nv+a++Lg++vylw+a+++++ +l+++ e++  +tsv+w ++g+++avG +++ev+i+D +++kkvr++ ghsarvg+
   Q: 136  ERTLDAPDIVNDYYLNLLDWSTTNVVAIGLGNTVYLWNASNSAINELTQVhEDDGPITSVAWAQDGNHIAVGLNNSEVQIWDHSTMKKVRSMRGHSARVGS 236
           689***********************************************555558********************************************* PP
   S: 102  LsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse...PlkkfkehkaavkaiawsPwqkslLasGG 199
           L+W+  +l++G+rd +il +dvr +++ +s+l+ah+qevCGlkw+  +k+LasGGnDn + +wd++s +    l++f++hkaavka+aw+P+q++lLasGG
   Q: 237  LAWHGSTLCTGGRDSKILYHDVRNRNHITSQLSAHEQEVCGLKWSLCGKQLASGGNDNLLYIWDSRSITssrHLFRFDQHKAAVKALAWCPYQTNLLASGG 337
           ****************************************************************98766556999************************** PP
   S: 200  GtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaivtaagDetlrfwklfd 298
           Gt+Drcikfwnt++g ll++idtgsqvcsl w ++++e++s+hGf+en+++lwkyps+ k++e+ gh++Rvl++a spdg +++taa+Detlrfw++f 
   Q: 338  GTTDRCIKFWNTQRGMLLNSIDTGSQVCSLQWNHHEQEILSSHGFSENQLILWKYPSMRKITEIMGHTSRVLHMAQSPDGFTVATAAADETLRFWQVFG 436
           *************************************************************************************************96 PP

Organism

Amborella trichopoda

Protein Sequence
(Fasta)

MAFRAFNHET RRLLLREWGN GGDSREHTML PSTRIVGDRF IPVRAAMDMD VSSYLLRSKN 60
RNSEMVVSPS KEEYRKRLAN IVLKDHNTSE NHTRILQFHA KPCKRKQSSA LADDEELLQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTTTA GGGCTTTTAA CCATGAAACC AGAAGATTGC TTTTGAGAGA ATGGGGAAAT 60
GGGGGTGATT CTAGAGAACA TACCATGTTA CCCTCTACAA GAATTGTGGT ATTTCATTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001545	Ailuropoda melanoleuca	45.97	4.00e-104	370.00
IUUC-Apl-003255	Anas platyrhynchos	46.45	1.00e-109	389.00
IUUC-Aca-004920	Anolis carolinensis	45.48	2.00e-99	355.00
IUUC-Bta-012625	Bos taurus	46.79	2.00e-104	371.00
IUUC-Cja-019132	Callithrix jacchus	47.16	5.00e-107	380.00
IUUC-Cfa-020780	Canis familiaris	46.68	3.00e-105	374.00
IUUC-Cpo-022223	Cavia porcellus	46.21	3.00e-98	350.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	52.07	4.00e-118	417.00
IUUC-Csa-023666	Chlorocebus sabaeus	46.68	1.00e-105	375.00
IUUC-Cme-027234	Cyanidioschyzon merolae	48.64	1.00e-107	382.00
IUUC-Dre-028026	Danio rerio	42.79	2.00e-97	348.00
IUUC-Dno-028865	Dasypus novemcinctus	45.86	7.00e-103	366.00
IUUC-Dor-030958	Dipodomys ordii	46.76	2.00e-102	364.00
IUUC-Dse-031391	Dothistroma septosporum	49.19	2.00e-96	345.00
IUUC-Dme-031905	Drosophila melanogaster	46.12	3.00e-110	390.00
IUUC-Ete-032387	Echinops telfairi	43.13	2.00e-96	344.00
IUUC-Eeu-035059	Erinaceus europaeus	42.75	5.00e-87	313.00
IUUC-Fca-036346	Felis catus	44.62	2.00e-91	327.00
IUUC-Fal-037558	Ficedula albicollis	45.97	3.00e-106	377.00
IUUC-Fox-037850	Fusarium oxysporum	47.61	2.00e-95	342.00
IUUC-Gmo-039284	Gadus morhua	42.16	1.00e-96	345.00
IUUC-Gga-040790	Gallus gallus	46.90	4.00e-109	387.00
IUUC-Ggo-045052	Gorilla gorilla	46.92	7.00e-106	376.00
IUUC-Hsa-046305	Homo sapiens	46.92	7.00e-106	376.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	46.68	3.00e-99	354.00
IUUC-Lma-052998	Leptosphaeria maculans	46.65	4.00e-94	337.00
IUUC-Laf-053742	Loxodonta africana	45.97	4.00e-104	370.00
IUUC-Mcc-054948	Macaca mulatta	46.68	1.00e-105	375.00
IUUC-Mga-060102	Meleagris gallopavo	46.90	2.00e-109	388.00
IUUC-Mmr-061615	Microcebus murinus	46.68	1.00e-105	375.00
IUUC-Mmu-063864	Mus musculus	46.68	5.00e-102	363.00
IUUC-Mpu-066502	Mustela putorius furo	47.52	5.00e-108	383.00
IUUC-Mlu-067277	Myotis lucifugus	46.60	6.00e-104	370.00
IUUC-Nle-070149	Nomascus leucogenys	46.45	7.00e-104	369.00
IUUC-Ont-071660	Oreochromis niloticus	43.31	5.00e-93	333.00
IUUC-Oan-073677	Ornithorhynchus anatinus	51.90	5.00e-96	343.00
IUUC-Ocu-073797	Oryctolagus cuniculus	46.68	8.00e-106	376.00
IUUC-Ola-086907	Oryzias latipes	42.12	5.00e-90	323.00
IUUC-Olu-087647	Ostreococcus lucimarinus	56.43	8.00e-138	482.00
IUUC-Oga-088184	Otolemur garnettii	46.43	1.00e-102	365.00
IUUC-Oar-090023	Ovis aries	47.67	7.00e-102	363.00
IUUC-Ptr-090935	Pan troglodytes	47.91	2.00e-104	371.00
IUUC-Pan-091845	Papio anubis	46.68	1.00e-105	375.00
IUUC-Psi-093188	Pelodiscus sinensis	45.62	1.00e-108	385.00
IUUC-Pma-094187	Petromyzon marinus	44.67	4.00e-95	340.00
IUUC-Pno-094809	Phaeosphaeria nodorum	47.45	5.00e-94	337.00
IUUC-Ppa-095687	Physcomitrella patens	60.93	7.00e-147	512.00
IUUC-Pab-098603	Pongo abelii	46.68	1.00e-105	375.00
IUUC-Pca-101062	Procavia capensis	46.68	3.00e-104	370.00
IUUC-Pva-102925	Pteropus vampyrus	47.02	3.00e-106	377.00
IUUC-Pte-104142	Pyrenophora teres	46.92	6.00e-94	337.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	46.92	7.00e-94	337.00
IUUC-Rno-106005	Rattus norvegicus	46.68	9.00e-102	362.00
IUUC-Sha-107472	Sarcophilus harrisii	44.34	1.00e-99	355.00
IUUC-Smo-108922	Selaginella moellendorffii	59.19	7.00e-150	522.00
IUUC-Sar-113092	Sorex araneus	44.02	1.00e-94	338.00
IUUC-Ssc-115710	Sus scrofa	46.30	1.00e-104	372.00
IUUC-Tgu-117100	Taeniopygia guttata	45.97	2.00e-106	378.00
IUUC-Tbe-127384	Tupaia belangeri	50.71	6.00e-86	310.00
IUUC-Ttr-128511	Tursiops truncatus	47.14	4.00e-105	374.00
IUUC-Vpa-130775	Vicugna pacos	38.81	2.00e-55	208.00
IUUC-Xtr-131993	Xenopus tropicalis	47.46	1.00e-107	382.00
IUUC-Xma-133332	Xiphophorus maculatus	42.72	6.00e-93	333.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence