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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064167
Ensembl Protein ID ENSMUSP00000029910.5
UniProt Accession O35242; A2AKK1; FAN_MOUSE
Genbank Protein ID AAB65394.1; CAM20130.1; CAM20130.1; CAM27232.1; CAM27232.1; EDL05686.1; AAI45962.1; AAI45964.1
Protein Name Protein FAN; Factor associated with neutral sphingomyelinase activation
Genbank Nucleotide ID AF013632; BX510318; AL772306; AL772306; BX510318; CH466538; BC145961; BC145963
Gene Name Nsmaf; Fan
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000028245.15 ENSMUST00000029910.11 ENSMUSP00000029910.5
ENSMUSG00000028245.15 ENSMUST00000124344.1 ENSMUSP00000120980.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
IID
Drug and target
GRAC
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 8.30e-24 83.8 715 743
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWD 29
           gH d v+ +++ + ++l sGs+D t+kvW+
   Q: 715  GHDDAVSKICWhN-DRLYSGSWDSTVKVWS 743
           8**********54.899************7 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MAFTRKRQRE QQLQLYSKER FSLLLLNLEE YYFEQHTAFH VQHQGSQEER KIRGSLKICS 60
KSVIFEPDAI SQPILKIPLR DCLKIGKHGE NGANKHFAKA KSWGISLIFS QIYFIKEHNI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064167|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGTGTAGGAC GCGGCTCCCG CGGCCTCAGG TCACTGCGCG CCCCTCCTCC GGGCCTGAGT 60
CACGGCGTCG CCCGAGTCCC CACGCGAGGA TGCTGCGGTG AGCGCCGTCC GGACGCCGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064167|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR000409--BEACH_dom
IPR004182--GRAM
IPR023362--PH-BEACH_dom
IPR011993--PH_dom-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50197--BEACH
PS51783--PH_BEACH
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF02138--Beach
PF02893--GRAM
PF00400--WD40
SMART

SM01026--Beach
SM00568--GRAM
SM00320--WD40
Gene Ontology

GO:0005123--F:death receptor binding
GO:0016230--F:sphingomyelin phosphodiesterase activator activity
GO:0043065--P:positive regulation of apoptotic process
KEGG mmu:18201
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001408 Ailuropoda melanoleuca 90.17 0.00e+00 1716.00
IUUC-Apl-004000 Anas platyrhynchos 78.96 0.00e+00 1505.00
IUUC-Aca-005253 Anolis carolinensis 76.39 0.00e+00 1453.00
IUUC-Ame-011654 Astyanax mexicanus 70.53 0.00e+00 1288.00
IUUC-Bta-013201 Bos taurus 87.09 0.00e+00 1661.00
IUUC-Cja-019039 Callithrix jacchus 91.33 0.00e+00 1721.00
IUUC-Cfa-020722 Canis familiaris 90.81 0.00e+00 1719.00
IUUC-Cpo-022247 Cavia porcellus 89.38 0.00e+00 1680.00
IUUC-Csa-023753 Chlorocebus sabaeus 91.82 0.00e+00 1740.00
IUUC-Cho-024757 Choloepus hoffmanni 90.46 0.00e+00 1385.00
IUUC-Dre-027693 Danio rerio 70.36 0.00e+00 1274.00
IUUC-Dno-028878 Dasypus novemcinctus 90.92 0.00e+00 1697.00
IUUC-Dor-030632 Dipodomys ordii 80.11 0.00e+00 1476.00
IUUC-Ete-032305 Echinops telfairi 82.66 0.00e+00 979.00
IUUC-Eca-034177 Equus caballus 92.45 0.00e+00 1750.00
IUUC-Eeu-034512 Erinaceus europaeus 72.56 0.00e+00 1170.00
IUUC-Fca-036028 Felis catus 89.28 0.00e+00 1695.00
IUUC-Fal-036685 Ficedula albicollis 78.19 0.00e+00 1441.00
IUUC-Gmo-038959 Gadus morhua 70.19 0.00e+00 1164.00
IUUC-Gga-040819 Gallus gallus 76.96 0.00e+00 1467.00
IUUC-Gac-041843 Gasterosteus aculeatus 68.61 0.00e+00 1300.00
IUUC-Ggo-045488 Gorilla gorilla 84.62 0.00e+00 1593.00
IUUC-Hsa-046714 Homo sapiens 91.89 0.00e+00 1739.00
IUUC-Itr-048950 Ictidomys tridecemlineatus 93.06 0.00e+00 1431.00
IUUC-Lch-050024 Latimeria chalumnae 63.07 0.00e+00 1118.00
IUUC-Loc-052831 Lepisosteus oculatus 73.51 0.00e+00 1398.00
IUUC-Laf-053693 Loxodonta africana 89.01 0.00e+00 1667.00
IUUC-Mcc-054769 Macaca mulatta 90.25 0.00e+00 1706.00
IUUC-Mga-059891 Meleagris gallopavo 77.14 0.00e+00 1427.00
IUUC-Mmr-060948 Microcebus murinus 91.41 0.00e+00 1751.00
IUUC-Mdo-062721 Monodelphis domestica 84.69 0.00e+00 1589.00
IUUC-Mpu-066243 Mustela putorius furo 90.22 0.00e+00 1747.00
IUUC-Mlu-068009 Myotis lucifugus 89.16 0.00e+00 1667.00
IUUC-Nle-069459 Nomascus leucogenys 91.33 0.00e+00 1725.00
IUUC-Opr-071145 Ochotona princeps 80.70 0.00e+00 1335.00
IUUC-Ont-071781 Oreochromis niloticus 68.08 0.00e+00 1313.00
IUUC-Oan-073456 Ornithorhynchus anatinus 82.90 0.00e+00 1558.00
IUUC-Ocu-073989 Oryctolagus cuniculus 91.63 0.00e+00 1776.00
IUUC-Ola-087535 Oryzias latipes 66.41 0.00e+00 1268.00
IUUC-Oga-089183 Otolemur garnettii 87.89 0.00e+00 1612.00
IUUC-Oar-090420 Ovis aries 87.82 0.00e+00 1649.00
IUUC-Ptr-091559 Pan troglodytes 91.74 0.00e+00 1774.00
IUUC-Pan-092213 Papio anubis 91.69 0.00e+00 1744.00
IUUC-Psi-093142 Pelodiscus sinensis 81.09 0.00e+00 1501.00
IUUC-Ppa-095631 Physcomitrella patens 40.39 4.00e-121 429.00
IUUC-Pfo-096451 Poecilia formosa 68.08 0.00e+00 1295.00
IUUC-Pab-098016 Pongo abelii 89.89 0.00e+00 1731.00
IUUC-Pca-100416 Procavia capensis 79.89 0.00e+00 1481.00
IUUC-Pva-102630 Pteropus vampyrus 88.00 0.00e+00 1654.00
IUUC-Rno-105516 Rattus norvegicus 96.96 0.00e+00 1867.00
IUUC-Sha-107116 Sarcophilus harrisii 85.02 0.00e+00 1606.00
IUUC-Smo-108747 Selaginella moellendorffii 40.18 6.00e-112 399.00
IUUC-Sar-113361 Sorex araneus 76.11 0.00e+00 1353.00
IUUC-Ssc-115516 Sus scrofa 88.14 0.00e+00 1669.00
IUUC-Tgu-117386 Taeniopygia guttata 76.20 0.00e+00 1451.00
IUUC-Tru-117680 Takifugu rubripes 67.98 0.00e+00 1257.00
IUUC-Tsy-119137 Tarsius syrichta 88.89 0.00e+00 1667.00
IUUC-Tni-120537 Tetraodon nigroviridis 66.02 0.00e+00 1285.00
IUUC-Tbe-127862 Tupaia belangeri 79.11 0.00e+00 1423.00
IUUC-Ttr-128350 Tursiops truncatus 84.30 0.00e+00 1563.00
IUUC-Xtr-131946 Xenopus tropicalis 70.43 0.00e+00 1305.00
Created Date 25-Jun-2017

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