iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++++ dpp+++sa+p+ + +++ew+ +ilGp++++YeggvF l+i+f+++YPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 31   RIQKELADITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 116
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 117  DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQ 166
           *********************************************99985 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MTEKEGSTPK KKESKVSMSK NSKLLSTSAK RIQKELADIT LDPPPNCSAG PKGDNIYEWR 60
STILGPPGSV YEGGVFFLDI TFTPEYPFKP PKVTFRTRIY HCNINSQGVI CLDILKDNWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGCCCTCC TGACAGCGGA GTTCCCTCTT TGCAGCGCCT GCATGGTCTG TGTTTCTGTT 60
TTGTTTCCTC CCCCTGCAGG GGCCGTTCGC GGGGTGGGGT GGGGGGTTCG CTATGTCGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0033523--P:histone H2B ubiquitination
GO:0010390--P:histone monoubiquitination
GO:0032020--P:ISG15-protein conjugation
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001532	Ailuropoda melanoleuca	100.00	7.00e-93	332.00
IUUC-Apl-004207	Anas platyrhynchos	100.00	2.00e-91	328.00
IUUC-Aca-005103	Anolis carolinensis	100.00	8.00e-92	329.00
IUUC-Cja-019311	Callithrix jacchus	100.00	7.00e-93	332.00
IUUC-Cfa-020017	Canis familiaris	100.00	7.00e-93	332.00
IUUC-Cpo-022266	Cavia porcellus	100.00	7.00e-93	332.00
IUUC-Cre-022791	Chlamydomonas reinhardtii	80.41	4.00e-70	256.00
IUUC-Csa-023538	Chlorocebus sabaeus	100.00	7.00e-93	332.00
IUUC-Cho-024986	Choloepus hoffmanni	78.36	1.00e-73	268.00
IUUC-Cin-025161	Ciona intestinalis	84.38	2.00e-75	275.00
IUUC-Csv-025982	Ciona savignyi	84.38	5.00e-82	296.00
IUUC-Cme-027286	Cyanidioschyzon merolae	70.06	2.00e-69	254.00
IUUC-Dre-027449	Danio rerio	88.30	1.00e-82	298.00
IUUC-Dno-029441	Dasypus novemcinctus	100.00	4.00e-74	269.00
IUUC-Dor-030450	Dipodomys ordii	100.00	3.00e-63	232.00
IUUC-Dme-032042	Drosophila melanogaster	87.12	1.00e-82	299.00
IUUC-Ete-032397	Echinops telfairi	98.25	1.00e-98	351.00
IUUC-Eca-033613	Equus caballus	100.00	2.00e-84	304.00
IUUC-Eeu-034931	Erinaceus europaeus	87.72	4.00e-80	290.00
IUUC-Fca-035467	Felis catus	100.00	6.00e-93	332.00
IUUC-Fal-036907	Ficedula albicollis	100.00	8.00e-92	329.00
IUUC-Gmo-039645	Gadus morhua	88.89	1.00e-83	302.00
IUUC-Gga-040403	Gallus gallus	100.00	8.00e-92	329.00
IUUC-Gac-041661	Gasterosteus aculeatus	88.89	1.00e-83	301.00
IUUC-Ggo-045507	Gorilla gorilla	100.00	7.00e-93	332.00
IUUC-Hsa-046576	Homo sapiens	100.00	7.00e-93	332.00
IUUC-Itr-048197	Ictidomys tridecemlineatus	100.00	4.00e-74	269.00
IUUC-Lch-050322	Latimeria chalumnae	96.51	3.00e-97	347.00
IUUC-Loc-052673	Lepisosteus oculatus	90.64	3.00e-85	307.00
IUUC-Laf-054313	Loxodonta africana	100.00	7.00e-93	332.00
IUUC-Mcc-055072	Macaca mulatta	97.90	2.00e-83	301.00
IUUC-Meu-056590	Macropus eugenii	100.00	6.00e-84	301.00
IUUC-Mmr-060791	Microcebus murinus	100.00	7.00e-93	332.00
IUUC-Mmu-063297	Mus musculus	100.00	9.00e-101	358.00
IUUC-Mpu-065698	Mustela putorius furo	98.84	6.00e-100	356.00
IUUC-Mlu-067897	Myotis lucifugus	97.90	2.00e-83	301.00
IUUC-Nle-069622	Nomascus leucogenys	100.00	7.00e-93	332.00
IUUC-Ont-072384	Oreochromis niloticus	91.23	8.00e-93	332.00
IUUC-Oan-073006	Ornithorhynchus anatinus	100.00	4.00e-74	269.00
IUUC-Ocu-074055	Oryctolagus cuniculus	100.00	7.00e-93	332.00
IUUC-Ola-086636	Oryzias latipes	92.94	3.00e-83	300.00
IUUC-Oga-088863	Otolemur garnettii	100.00	7.00e-93	332.00
IUUC-Oar-089803	Ovis aries	98.84	6.00e-100	356.00
IUUC-Ptr-090914	Pan troglodytes	100.00	7.00e-93	332.00
IUUC-Pan-092786	Papio anubis	100.00	7.00e-93	332.00
IUUC-Psi-093923	Pelodiscus sinensis	100.00	8.00e-93	332.00
IUUC-Pma-094642	Petromyzon marinus	95.24	7.00e-71	258.00
IUUC-Ppa-095789	Physcomitrella patens	76.67	3.00e-68	250.00
IUUC-Pfo-096966	Poecilia formosa	91.23	7.00e-83	299.00
IUUC-Pab-098614	Pongo abelii	100.00	7.00e-93	332.00
IUUC-Pva-102561	Pteropus vampyrus	97.90	2.00e-83	301.00
IUUC-Sha-106897	Sarcophilus harrisii	100.00	1.00e-84	304.00
IUUC-Ssc-116298	Sus scrofa	97.96	7.00e-85	305.00
IUUC-Tgu-116958	Taeniopygia guttata	100.00	3.00e-88	317.00
IUUC-Tru-118531	Takifugu rubripes	93.71	3.00e-80	291.00
IUUC-Tsy-119002	Tarsius syrichta	92.57	9.00e-80	289.00
IUUC-Tni-120349	Tetraodon nigroviridis	94.51	1.00e-81	295.00
IUUC-Ttr-128356	Tursiops truncatus	96.20	6.00e-88	316.00
IUUC-Vpa-130232	Vicugna pacos	96.45	3.00e-79	287.00
IUUC-Xtr-132547	Xenopus tropicalis	100.00	1.00e-85	308.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence