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Tag Content
UUCD2 ID IUUC-Aca-004402
UUCD1 version UUC-AnC-01030
Ensembl Protein ID ENSACAP00000014104.2
UniProt Accession H9GKZ6; H9GKZ6_ANOCA
Protein Name Uncharacterized protein
Gene Name CYLD
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSACAG00000014388.2 ENSACAT00000014393.2 ENSACAP00000014104.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 8.50e-26 90.9 589 946
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeq 89
           G++ + N+CY++S+L cL++++++ + +l + kek + e ++e+++ l +++ + ++     + +k ++ r++l+++++++  f++ e+
   Q: 589  GIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQALLRTEIVNPLRIYGyVCATKIMKLRKILEKVEAAS-GFTSEEK 676
           999***************************99999999999999999*********988789***************9665.69***** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksq.ik...clecdnvs.sreepfldls 173
            D +Efl++l++++ +       k ++  ++ +++   ++  +k++k +  +i++l+++++ ++ +k    ++c  ++  r+ + +++ 
   Q: 677  ADPEEFLNILFHHILRVE--PLLKIRSAGQKVQDCYFYQIFMDKNEKVGVPTIQQLLEWSFINSnLKfaeAPSCLIIQmPRFGKDFKMF 763
           ****************99..88999999999999**************************9854144444799****999********9 PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenk.yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
            ++  + e    +++d+Le+  ++++++g  + y+c++c++++e +   k+k+++++   +           ++++ ++ v++p+ L  
   Q: 764  NKIFPSLEL---NITDLLEDTPRQCRICGGLAmYECRECYEDTEISAG-KIKQFCKTCNTQVHLH-----PRRQSHKFNPVSLPKDLPD 843
           999999988...***************987655**********96655.8888888655444433.....1233455889999977543 PP
   S: 262  spfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk..WllfdD.............skVtevke.eevleetg....... 327
             + +        ++k eL+av++ +      HYva+vk  kg+  Wl fd               +Vt+++e  e l+++        
   Q: 844  WDWRHG----CIPCQKMELFAVLCIET----SHYVAFVKYGKGDsaWLFFDSmadrdggqngfniPQVTPCPEvGEYLKMSVeelhsld 924
           334333....2339**********999....9********998899*****9999********99777777654566665556677788 PP
   S: 328  ............staYvlfYkr 337
                       ++aY+++Y++
   Q: 925  srriqgcarrllCDAYMCMYQS 946
           888888999***********85 PP
   
Organism Anolis carolinensis
Protein Sequence
(Fasta)
MSSWSQDKGS SPYWEDRIFY LLLQECSIID KQTQKLLKVP GSIGQFVQDR SSGGHTRSNP 60
SSKSKNQIGI KILEQLHAIL FVDETEVVEI DGKSGNVMLK LTPCLRAGVI FQRSPRLHSQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aca-004402|DUB,USP|Anolis carolinensis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAGTTCGT GGAGTCAAGA TAAAGGCAGC TCTCCCTATT GGGAAGACCG TATATTTTAC 60
TTACTTCTCC AAGAATGTAG CATTATAGAC AAACAGACTC AAAAATTATT GAAAGTACCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aca-004402|DUB,USP|Anolis carolinensis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR000938--CAP-Gly_domain
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50245--CAP_GLY_2
PS00972--USP_1
PS50235--USP_3
Pfam

PF01302--CAP_GLY
PF00443--UCH
SMART

SM01052--CAP_GLY
Gene Ontology

GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0097542--C:ciliary tip
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0030496--C:midbody
GO:0005819--C:spindle
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0043369--P:CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
GO:0048872--P:homeostasis of number of cells
GO:0045087--P:innate immune response
GO:0070266--P:necroptotic process
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0045581--P:negative regulation of T cell differentiation
GO:1903829--P:positive regulation of cellular protein localization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0045582--P:positive regulation of T cell differentiation
GO:0050862--P:positive regulation of T cell receptor signaling pathway
GO:1990108--P:protein linear deubiquitination
GO:0045577--P:regulation of B cell differentiation
GO:1902017--P:regulation of cilium assembly
GO:2001242--P:regulation of intrinsic apoptotic signaling pathway
GO:0070507--P:regulation of microtubule cytoskeleton organization
GO:0007346--P:regulation of mitotic cell cycle
GO:0043393--P:regulation of protein binding
GO:0010803--P:regulation of tumor necrosis factor-mediated signaling pathway
GO:1901026--P:ripoptosome assembly involved in necroptotic process
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001298 Ailuropoda melanoleuca 81.10 0.00e+00 1586.00
IUUC-Apl-003356 Anas platyrhynchos 84.19 0.00e+00 1586.00
IUUC-Ame-011581 Astyanax mexicanus 64.27 0.00e+00 1139.00
IUUC-Bta-012359 Bos taurus 80.94 0.00e+00 1581.00
IUUC-Cel-018528 Caenorhabditis elegans 34.81 5.00e-56 213.00
IUUC-Cja-018797 Callithrix jacchus 81.10 0.00e+00 1585.00
IUUC-Cfa-020264 Canis familiaris 81.04 0.00e+00 1581.00
IUUC-Cpo-022057 Cavia porcellus 81.10 0.00e+00 1589.00
IUUC-Csa-023093 Chlorocebus sabaeus 81.04 0.00e+00 1585.00
IUUC-Cho-024486 Choloepus hoffmanni 85.99 4.00e-159 555.00
IUUC-Cin-025179 Ciona intestinalis 44.42 1.00e-118 419.00
IUUC-Dre-028233 Danio rerio 63.51 0.00e+00 1150.00
IUUC-Dno-029496 Dasypus novemcinctus 80.94 0.00e+00 1579.00
IUUC-Dor-030919 Dipodomys ordii 76.30 0.00e+00 1471.00
IUUC-Dme-032159 Drosophila melanogaster 46.05 2.00e-123 435.00
IUUC-Ete-032734 Echinops telfairi 76.33 0.00e+00 1476.00
IUUC-Eca-033350 Equus caballus 81.13 0.00e+00 1596.00
IUUC-Eeu-034566 Erinaceus europaeus 93.55 2.00e-109 390.00
IUUC-Fca-035632 Felis catus 75.47 0.00e+00 1025.00
IUUC-Fal-037313 Ficedula albicollis 78.83 0.00e+00 1471.00
IUUC-Gmo-039239 Gadus morhua 63.71 0.00e+00 1115.00
IUUC-Gga-040668 Gallus gallus 83.84 0.00e+00 1585.00
IUUC-Gac-042630 Gasterosteus aculeatus 64.15 0.00e+00 1107.00
IUUC-Ggo-044462 Gorilla gorilla 80.89 0.00e+00 1581.00
IUUC-Hsa-045846 Homo sapiens 80.89 0.00e+00 1581.00
IUUC-Itr-048894 Ictidomys tridecemlineatus 84.86 0.00e+00 750.00
IUUC-Lch-050303 Latimeria chalumnae 65.91 0.00e+00 1177.00
IUUC-Loc-052190 Lepisosteus oculatus 66.74 0.00e+00 1167.00
IUUC-Laf-054480 Loxodonta africana 90.23 0.00e+00 746.00
IUUC-Mcc-055849 Macaca mulatta 81.10 0.00e+00 1585.00
IUUC-Meu-056755 Macropus eugenii 65.31 0.00e+00 666.00
IUUC-Mga-059561 Meleagris gallopavo 83.58 0.00e+00 1579.00
IUUC-Mmr-060942 Microcebus murinus 80.79 0.00e+00 1566.00
IUUC-Mdo-062618 Monodelphis domestica 80.79 0.00e+00 1569.00
IUUC-Mmu-063843 Mus musculus 79.65 0.00e+00 1519.00
IUUC-Mpu-066919 Mustela putorius furo 81.15 0.00e+00 1585.00
IUUC-Mlu-066983 Myotis lucifugus 78.12 0.00e+00 1508.00
IUUC-Nle-069893 Nomascus leucogenys 81.00 0.00e+00 1582.00
IUUC-Opr-071181 Ochotona princeps 72.51 0.00e+00 1284.00
IUUC-Ont-071697 Oreochromis niloticus 62.76 0.00e+00 1095.00
IUUC-Oan-073658 Ornithorhynchus anatinus 80.86 0.00e+00 1563.00
IUUC-Ocu-074954 Oryctolagus cuniculus 81.10 0.00e+00 1588.00
IUUC-Ola-086523 Oryzias latipes 61.93 0.00e+00 1073.00
IUUC-Oga-089003 Otolemur garnettii 81.10 0.00e+00 1588.00
IUUC-Oar-090376 Ovis aries 80.66 0.00e+00 1585.00
IUUC-Ptr-090520 Pan troglodytes 79.13 0.00e+00 1530.00
IUUC-Pan-092281 Papio anubis 81.04 0.00e+00 1585.00
IUUC-Psi-093047 Pelodiscus sinensis 84.61 0.00e+00 1516.00
IUUC-Pma-094575 Petromyzon marinus 56.28 2.00e-66 245.00
IUUC-Pfo-096358 Poecilia formosa 63.40 0.00e+00 1046.00
IUUC-Pab-097740 Pongo abelii 80.79 0.00e+00 1576.00
IUUC-Pca-100461 Procavia capensis 71.83 0.00e+00 1244.00
IUUC-Pva-102134 Pteropus vampyrus 72.27 0.00e+00 1380.00
IUUC-Rno-105807 Rattus norvegicus 78.23 0.00e+00 1472.00
IUUC-Sha-107236 Sarcophilus harrisii 80.38 0.00e+00 1515.00
IUUC-Sar-113366 Sorex araneus 94.90 0.00e+00 907.00
IUUC-Tgu-117201 Taeniopygia guttata 80.56 0.00e+00 1507.00
IUUC-Tru-117953 Takifugu rubripes 63.59 0.00e+00 1088.00
IUUC-Tsy-119610 Tarsius syrichta 79.02 0.00e+00 1537.00
IUUC-Tni-120743 Tetraodon nigroviridis 53.56 4.00e-135 475.00
IUUC-Tbe-128155 Tupaia belangeri 70.13 0.00e+00 659.00
IUUC-Ttr-128942 Tursiops truncatus 74.50 0.00e+00 960.00
IUUC-Vpa-130281 Vicugna pacos 71.44 0.00e+00 1343.00
IUUC-Xtr-132627 Xenopus tropicalis 71.56 0.00e+00 1285.00
Created Date 25-Jun-2017

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