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Tag Content
iUUCD ID IUUC-Fal-037313
Ensembl Protein ID ENSFALP00000000081.1
UniProt Accession U3JBC7; U3JBC7_FICAL
Genbank Protein ID ENSFALP00000000081
Protein Name Uncharacterized protein
Genbank Nucleotide ID AGTO01010907
Gene Name CYLD
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFALG00000000075.1 ENSFALT00000000081.1 ENSFALP00000000081.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 7.10e-24 84.3 545 901
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp.kepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           G++ + N+CY++S+L cL++++++ + +l   ++++n+ ++ +e+++ l +++ + ++     + +k ++ r++l+++++++    ++e
   Q: 545  GIQGHYNSCYLDSTLFCLFSFSSVLDTVLL-RPKEMNDVEYySETQELLRTEIVNPLRIYGyVCATKIMKLRKILEKVEAASGF--TSE 630
           999***************************.666666665515555566678888888776899**************988875..899 PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksq.ik...clecdnvs.sreepfldl 172
           ++D +Efl++l++++ +       k ++  ++ +++   ++  +k++k +  +i++l+++++ ++ +k    ++c  ++  r+ + +++
   Q: 631  EKDPEEFLNILFHHILRVE--PLLKIRSAGQKVQDCYFYQIFMDKNEKVGVPTIQQLLEWSFINSnLKfaeAPSCLIIQmPRFGKDFKM 717
           *****************99..88999999999999**************************9854144444799****999******** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelege.nkyycekckkkqeaekklklkklPe....vLilhLkRfsfseeqksrekinkkvefp 256
             ++  + e    +++d+Le+  ++++++    +y+c++c+++++ +   k+k++++      +lh kR          ++ ++ +++p
   Q: 718  FNKIFPSLEL---NITDLLEDTPRQCRICRGlAMYECRECYEDTDISAG-KIKQFCKtcntQVHLHPKRQ---------SHKFNALSLP 793
           9999999988...**************9865166**********85444.66666663224577777777.........2335567777 PP
   S: 257  leL...dlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk..WllfdD.............skVtevke.eevleet 326
           + L   d ++ c+        ++k eL+av++ +      HYva+vk  +++  Wl fd               +Vt+++e +e l+++
   Q: 794  KDLpdwDWRHGCIP-------SQKMELFAVLCIET----SHYVAFVKYGRDDsaWLFFDSmadrdggqngfniPQVTPCPEvAEYLKMS 871
           55411144455555.......89*********999....9********666667*****9999**********9999997668888877 PP
   S: 327  g...................staYvlfYkr 337
                               ++aY+++Y++
   Q: 872  LeelhsldsrkiqgcarrllCDAYMCMYQS 901
           689999999999999*************95 PP
   
Organism Ficedula albicollis
Protein Sequence
(Fasta)
MNSGLWSQEK ASSSYWEERI FYLLLQECSV IDKQTQKLLK VPKGSIGQFF QDRSSVAHSR 60
NIPCKGKKLQ IGLKILEQPH AILFVDEKDV IEINEKLAEL LLAITNCEER YSLFKSKSRL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Fal-037313|DUB,USP|Ficedula albicollis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTTAAACTG TTGAACAGAC TTTCTCTTTT AATATATTAT TTCCATGCAT ACTTACTAAA 60
ATTAAAATTA ATTATTTCTG TAAATGAAGT AGGAAAAATC AGAATCCTTG TATTGTCAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fal-037313|DUB,USP|Ficedula albicollis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR000938--CAP-Gly_domain
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50245--CAP_GLY_2
PS00972--USP_1
PS50235--USP_3
Pfam

PF01302--CAP_GLY
PF00443--UCH
SMART

SM01052--CAP_GLY
Gene Ontology

GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0097542--C:ciliary tip
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0030496--C:midbody
GO:0005819--C:spindle
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0043369--P:CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
GO:0048872--P:homeostasis of number of cells
GO:0045087--P:innate immune response
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0045581--P:negative regulation of T cell differentiation
GO:1903829--P:positive regulation of cellular protein localization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0045582--P:positive regulation of T cell differentiation
GO:0050862--P:positive regulation of T cell receptor signaling pathway
GO:1990108--P:protein linear deubiquitination
GO:0045577--P:regulation of B cell differentiation
GO:1902017--P:regulation of cilium assembly
GO:2001242--P:regulation of intrinsic apoptotic signaling pathway
GO:0070507--P:regulation of microtubule cytoskeleton organization
GO:0007346--P:regulation of mitotic cell cycle
GO:0043393--P:regulation of protein binding
GO:0010803--P:regulation of tumor necrosis factor-mediated signaling pathway
GO:1901026--P:ripoptosome assembly involved in necroptotic process
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001298 Ailuropoda melanoleuca 82.24 0.00e+00 1632.00
IUUC-Apl-003356 Anas platyrhynchos 91.93 0.00e+00 1742.00
IUUC-Aca-004402 Anolis carolinensis 78.83 0.00e+00 1453.00
IUUC-Ago-007983 Ashbya gossypii 29.69 3.50e-01 30.80
IUUC-Ame-011581 Astyanax mexicanus 65.80 0.00e+00 1177.00
IUUC-Bta-012359 Bos taurus 82.29 0.00e+00 1629.00
IUUC-Cel-018528 Caenorhabditis elegans 35.16 1.00e-58 221.00
IUUC-Cja-018797 Callithrix jacchus 82.13 0.00e+00 1630.00
IUUC-Cfa-020264 Canis familiaris 82.60 0.00e+00 1636.00
IUUC-Cpo-022057 Cavia porcellus 81.92 0.00e+00 1629.00
IUUC-Csa-023093 Chlorocebus sabaeus 82.70 0.00e+00 1636.00
IUUC-Cho-024486 Choloepus hoffmanni 84.97 7.00e-158 551.00
IUUC-Cin-025179 Ciona intestinalis 43.89 6.00e-118 417.00
IUUC-Dre-028233 Danio rerio 65.87 0.00e+00 1209.00
IUUC-Dno-029496 Dasypus novemcinctus 82.39 0.00e+00 1636.00
IUUC-Dor-030919 Dipodomys ordii 77.43 0.00e+00 1510.00
IUUC-Dme-032159 Drosophila melanogaster 46.14 4.00e-124 438.00
IUUC-Ete-032734 Echinops telfairi 77.85 0.00e+00 1517.00
IUUC-Eca-033350 Equus caballus 82.60 0.00e+00 1643.00
IUUC-Eeu-034566 Erinaceus europaeus 91.94 2.00e-107 383.00
IUUC-Fca-035632 Felis catus 77.58 0.00e+00 1075.00
IUUC-Gmo-039239 Gadus morhua 64.70 0.00e+00 1160.00
IUUC-Gga-040668 Gallus gallus 91.09 0.00e+00 1728.00
IUUC-Gac-042630 Gasterosteus aculeatus 65.56 0.00e+00 1161.00
IUUC-Ggo-044462 Gorilla gorilla 82.24 0.00e+00 1628.00
IUUC-Hsa-045846 Homo sapiens 82.24 0.00e+00 1627.00
IUUC-Itr-048894 Ictidomys tridecemlineatus 85.12 0.00e+00 765.00
IUUC-Lch-050303 Latimeria chalumnae 67.80 0.00e+00 1232.00
IUUC-Loc-052190 Lepisosteus oculatus 67.71 0.00e+00 1222.00
IUUC-Laf-054480 Loxodonta africana 88.97 0.00e+00 734.00
IUUC-Mcc-055849 Macaca mulatta 82.65 0.00e+00 1634.00
IUUC-Meu-056755 Macropus eugenii 68.42 0.00e+00 723.00
IUUC-Mga-059561 Meleagris gallopavo 90.39 0.00e+00 1715.00
IUUC-Mmr-060942 Microcebus murinus 82.24 0.00e+00 1618.00
IUUC-Mdo-062618 Monodelphis domestica 82.24 0.00e+00 1628.00
IUUC-Mmu-063843 Mus musculus 80.77 0.00e+00 1563.00
IUUC-Mpu-066919 Mustela putorius furo 82.60 0.00e+00 1638.00
IUUC-Mlu-066983 Myotis lucifugus 79.66 0.00e+00 1561.00
IUUC-Nle-069893 Nomascus leucogenys 82.34 0.00e+00 1629.00
IUUC-Opr-071181 Ochotona princeps 74.78 0.00e+00 1355.00
IUUC-Ont-071697 Oreochromis niloticus 65.84 0.00e+00 1154.00
IUUC-Oan-073658 Ornithorhynchus anatinus 82.29 0.00e+00 1602.00
IUUC-Ocu-074954 Oryctolagus cuniculus 82.55 0.00e+00 1637.00
IUUC-Ola-086523 Oryzias latipes 65.04 0.00e+00 1136.00
IUUC-Oga-089003 Otolemur garnettii 82.55 0.00e+00 1640.00
IUUC-Oar-090376 Ovis aries 81.89 0.00e+00 1632.00
IUUC-Ptr-090520 Pan troglodytes 80.46 0.00e+00 1579.00
IUUC-Pan-092281 Papio anubis 82.70 0.00e+00 1636.00
IUUC-Psi-093047 Pelodiscus sinensis 88.26 0.00e+00 1581.00
IUUC-Pma-094575 Petromyzon marinus 54.79 8.00e-67 246.00
IUUC-Pfo-096358 Poecilia formosa 65.45 0.00e+00 1115.00
IUUC-Pab-097740 Pongo abelii 82.03 0.00e+00 1624.00
IUUC-Pca-100461 Procavia capensis 73.21 0.00e+00 1290.00
IUUC-Pva-102134 Pteropus vampyrus 73.46 0.00e+00 1425.00
IUUC-Rno-105807 Rattus norvegicus 79.77 0.00e+00 1535.00
IUUC-Sha-107236 Sarcophilus harrisii 82.71 0.00e+00 1581.00
IUUC-Sar-113366 Sorex araneus 94.44 0.00e+00 906.00
IUUC-Tgu-117201 Taeniopygia guttata 91.73 0.00e+00 1718.00
IUUC-Tru-117953 Takifugu rubripes 64.69 0.00e+00 1153.00
IUUC-Tsy-119610 Tarsius syrichta 80.15 0.00e+00 1585.00
IUUC-Tni-120743 Tetraodon nigroviridis 38.83 1.00e-150 527.00
IUUC-Tbe-128155 Tupaia belangeri 69.90 0.00e+00 676.00
IUUC-Ttr-128942 Tursiops truncatus 76.91 0.00e+00 1510.00
IUUC-Vpa-130281 Vicugna pacos 72.38 0.00e+00 1388.00
IUUC-Xtr-132627 Xenopus tropicalis 73.80 0.00e+00 1337.00
Created Date 25-Jun-2017

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