iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052190

Ensembl Protein ID

ENSLOCP00000008861.1

UniProt Accession

W5MKF2; W5MKF2_LEPOC

Genbank Protein ID

ENSLOCP00000008861

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01020886

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000007312.1	ENSLOCT00000008872.1	ENSLOCP00000008861.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.20e-18	65.5	589	944

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeq 89
           G++ + N+CY++S+L cL++++++ + +l + + k + e + e+++ l +++ + ++     + +k+++ r++l+++++++    ++e+
   Q: 589  GIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRPRAKSDVEYYRETQELLRTEIVNPLRIHGyVCATKVMKLRRILEKVEAASGF--TSEE 675
           999***************************99999999999999999999999999877679***************988875..899* PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk.sqik...clecdnvs.sreepfldls 173
           +D +Efl +l++++ +         ++  ++ +++   ++  ek++k +  + ++l+++++  s++k    ++c  ++  r+ + +++ 
   Q: 676  KDPEEFLIILFHHILRVD--PLLRLRSAGQKVQDCYFYQIFMEKNEKVGVPTSQQLLEWSFInSDLKfaeAPSCLIIQmPRFGKDFKMF 762
           **************9977..667777888888899999**********************9843444334899****999********9 PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenk.yycekckkkqeaekklklkklPe..vLilhLkRfsfseeqksrekinkkvefpleL 259
            ++  + e    +++d+Le+  +e++++g  + ++c++c+++ + +   k+k+++e   + +hL          +r++ +  +++p+eL
   Q: 763  NKIFPSLEL---NITDLLEDTPRECRICGGLAfFECRECYEDPDITAG-KIKQFCEkcNMQVHLHPR-------RRSHRQGALSVPKEL 840
           999999988...*****************999789********86665.999999955445555444.......3445567899**888 PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................ekgkWllfdDskVte 316
           +      ++      +++ eL+av++ +      HYva+vk                                 e g +l+++ ++ ++
   Q: 841  QEG---GRQGGF--PRQRMELFAVLCIET----SHYVAFVKYgaadsawlffdsmadrdggqngfnipqvtpcpEVGAYLKMSPEELHA 920
           766...232333..399*********999....9********77666666666666666666555555555554445566666688888 PP
   S: 317  vkeeevleetg...staYvlfYkr 337
           ++ ++++ + +   ++aY+++Y++
   Q: 921  LDPKSIQGFARrllCDAYMCMYQS 944
           88888888777***********95 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSSGLWSQEK PSAGFREDLR YYVVVQECLL EKPPQKTLKI PRGSIGQTCV ERNSLGRPLP 60
TAKGKRSLRI LDQTNVVLSM DEKDVQELDE KLAELLFAIT NCEERYGLFR NKPRLDRVRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCCCAATG GATGTGGACT CCGGTCAGCG AGAGCCATGC TGACAGACTG CAGAAGGATG 60
TGGGCAGACC GATGTCTCCA GGGAACGGCC CCATGAGCTG TCCGCTCTCT CGTCTTGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000938--CAP-Gly_domain
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50245--CAP_GLY_2
PS00972--USP_1
PS50235--USP_3

Pfam

PF01302--CAP_GLY
PF00443--UCH

SMART

SM01052--CAP_GLY

Gene Ontology

GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:1990108--P:protein linear deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001298	Ailuropoda melanoleuca	69.71	0.00e+00	1329.00
IUUC-Apl-003356	Anas platyrhynchos	70.58	0.00e+00	1325.00
IUUC-Aca-004402	Anolis carolinensis	66.74	0.00e+00	1173.00
IUUC-Ame-011581	Astyanax mexicanus	81.43	0.00e+00	1465.00
IUUC-Bta-012359	Bos taurus	69.72	0.00e+00	1327.00
IUUC-Cja-018797	Callithrix jacchus	69.81	0.00e+00	1321.00
IUUC-Cfa-020264	Canis familiaris	69.72	0.00e+00	1327.00
IUUC-Cpo-022057	Cavia porcellus	69.81	0.00e+00	1337.00
IUUC-Csa-023093	Chlorocebus sabaeus	70.03	0.00e+00	1328.00
IUUC-Cho-024486	Choloepus hoffmanni	76.14	2.00e-135	476.00
IUUC-Cin-025179	Ciona intestinalis	45.34	4.00e-119	421.00
IUUC-Dre-028233	Danio rerio	79.48	0.00e+00	1479.00
IUUC-Dno-029496	Dasypus novemcinctus	70.37	0.00e+00	1331.00
IUUC-Dor-030919	Dipodomys ordii	83.33	0.00e+00	833.00
IUUC-Dme-032159	Drosophila melanogaster	45.54	1.00e-121	430.00
IUUC-Ete-032734	Echinops telfairi	66.08	0.00e+00	1222.00
IUUC-Eca-033350	Equus caballus	69.72	0.00e+00	1332.00
IUUC-Eeu-034566	Erinaceus europaeus	79.57	4.00e-88	319.00
IUUC-Fca-035632	Felis catus	64.09	0.00e+00	842.00
IUUC-Fal-037313	Ficedula albicollis	67.05	0.00e+00	1245.00
IUUC-Gmo-039239	Gadus morhua	82.35	0.00e+00	1479.00
IUUC-Gga-040668	Gallus gallus	70.69	0.00e+00	1323.00
IUUC-Gac-042630	Gasterosteus aculeatus	80.31	0.00e+00	1441.00
IUUC-Ggo-044462	Gorilla gorilla	69.71	0.00e+00	1319.00
IUUC-Hsa-045846	Homo sapiens	69.71	0.00e+00	1318.00
IUUC-Itr-048894	Ictidomys tridecemlineatus	72.75	2.00e-176	611.00
IUUC-Lch-050303	Latimeria chalumnae	66.43	0.00e+00	1167.00
IUUC-Laf-054480	Loxodonta africana	79.95	0.00e+00	645.00
IUUC-Mcc-055849	Macaca mulatta	69.81	0.00e+00	1322.00
IUUC-Meu-056755	Macropus eugenii	57.75	2.00e-162	566.00
IUUC-Mga-059561	Meleagris gallopavo	70.05	0.00e+00	1313.00
IUUC-Mmr-060942	Microcebus murinus	69.50	0.00e+00	1312.00
IUUC-Mdo-062618	Monodelphis domestica	69.61	0.00e+00	1325.00
IUUC-Mmu-063843	Mus musculus	68.78	0.00e+00	1276.00
IUUC-Mpu-066919	Mustela putorius furo	69.93	0.00e+00	1332.00
IUUC-Mlu-066983	Myotis lucifugus	68.47	0.00e+00	1284.00
IUUC-Nle-069893	Nomascus leucogenys	69.71	0.00e+00	1318.00
IUUC-Opr-071181	Ochotona princeps	62.46	0.00e+00	1072.00
IUUC-Ont-071697	Oreochromis niloticus	81.15	0.00e+00	1457.00
IUUC-Oan-073658	Ornithorhynchus anatinus	69.82	0.00e+00	1307.00
IUUC-Ocu-074954	Oryctolagus cuniculus	69.61	0.00e+00	1325.00
IUUC-Ola-086523	Oryzias latipes	80.33	0.00e+00	1426.00
IUUC-Oga-089003	Otolemur garnettii	70.02	0.00e+00	1332.00
IUUC-Oar-090376	Ovis aries	69.52	0.00e+00	1327.00
IUUC-Ptr-090520	Pan troglodytes	68.15	0.00e+00	1275.00
IUUC-Pan-092281	Papio anubis	70.03	0.00e+00	1328.00
IUUC-Psi-093047	Pelodiscus sinensis	73.37	0.00e+00	1288.00
IUUC-Pma-094575	Petromyzon marinus	57.41	2.00e-68	251.00
IUUC-Pfo-096358	Poecilia formosa	80.42	0.00e+00	1369.00
IUUC-Pab-097740	Pongo abelii	69.61	0.00e+00	1317.00
IUUC-Pca-100461	Procavia capensis	61.46	0.00e+00	1029.00
IUUC-Pva-102134	Pteropus vampyrus	62.66	0.00e+00	1149.00
IUUC-Rno-105807	Rattus norvegicus	68.37	0.00e+00	1264.00
IUUC-Sha-107236	Sarcophilus harrisii	69.70	0.00e+00	1297.00
IUUC-Sar-113366	Sorex araneus	83.78	0.00e+00	791.00
IUUC-Tgu-117201	Taeniopygia guttata	67.32	0.00e+00	1245.00
IUUC-Tru-117953	Takifugu rubripes	81.35	0.00e+00	1446.00
IUUC-Tsy-119610	Tarsius syrichta	67.95	0.00e+00	1284.00
IUUC-Tni-120743	Tetraodon nigroviridis	54.00	3.00e-136	479.00
IUUC-Tbe-128155	Tupaia belangeri	60.82	2.00e-160	559.00
IUUC-Ttr-128942	Tursiops truncatus	64.94	0.00e+00	1214.00
IUUC-Vpa-130281	Vicugna pacos	61.41	0.00e+00	1118.00
IUUC-Xtr-132627	Xenopus tropicalis	64.21	0.00e+00	1143.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence