iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096358

Ensembl Protein ID

ENSPFOP00000015841.1

UniProt Accession

A0A087YCT8; A0A087YCT8_POEFO

Genbank Protein ID

ENSPFOP00000015841

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01004724

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000015716.1	ENSPFOT00000015863.1	ENSPFOP00000015841.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-20	74.0	584	940

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeq 89
           G++ + N+CY++S+L cL++++++ + +l + ++k++ e + e+++ l +++ + ++     + +k+++ r++l+++++++    ++e+
   Q: 584  GIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPRSKTDVEYYRETQELLRTEIVNPLRIHGyVCATKVMKLRRILEKVEAASGF--TSEE 670
           999***************************99999999999999999999999999877679***************988875..899* PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk.sqik...clecdnvs.sreepfldls 173
           +D +Efl++l++++ +       k ++  ++ +++   ++  ekk+k +  + ++l+++++  s++k    ++c  ++  r+ + +++ 
   Q: 671  KDPEEFLNILFHHILRVD--PLLKLRSAGQKVQDCYFYQIFMEKKDKVGVPTSQQLLEWSFItSDLKfaeAPSCLIIQmPRFGKDFKMF 757
           **************9977..778889999999999************************98645566444799**99999********9 PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenk.yycekckkkqeaekklklkklPe....vLilhLkRfsfseeqksrekinkkvefpl 257
            ++  + e    +++d+Le+  +e++++   + y+c+ c+++ + +   k+k+++e      +lh kR           + ++k+++p+
   Q: 758  NKIFPSLEL---DITDLLEDTPRECRICAGLAlYECRDCYEDGDITAG-KIKQFCEkcntQVHLHPKRK---------AHRHNKLSVPK 833
           999999988...***************988777*******99985544.77777765545788888888.........34468999998 PP
   S: 258  eLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk..WllfdD.............skVtevke.eevleetg... 327
           eL+  +  +        +++ eL+av++ +      HYva+vk  + +  Wl fd               +V++++e e  l++t    
   Q: 834  ELQEGQGRQG--GFP--RQRMELFAVLCIET----SHYVAFVKYGSADsaWLFFDSmadrdggqngfniPQVSPCPEvEAYLKMTPeel 914
           8877644433..443..99*********999....9********666667999999999999999999988888876567777666888 PP
   S: 328  ................staYvlfYkr 337
                           ++aY+++Y++
   Q: 915  htldpksiqgqarrllCDAYMCMYQS 940
           8888888888899***********95 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MSSALWEKPS GGFREDWRFY MVVKECTVEK PTQKTLRIPR GSLGQACQER NSLGRTLPPC 60
KGKKSLRILD QTNVVLSLDE RDVVELDEKL AELLFPITNC EERCNLLCDE DRLERVRDID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGGCCAAT GTCTATGAGA GAGCGCAGTG ACGTCACGCC ATACCCGACG GTGAGGTCGT 60
CTCCTGTAAA TAATAAATGT AGTCTATGTA TGCTGCGTTA TAGCGTTTGA AGTTTTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000938--CAP-Gly_domain
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50245--CAP_GLY_2
PS00972--USP_1
PS50235--USP_3

Pfam

PF01302--CAP_GLY
PF00443--UCH

SMART

SM01052--CAP_GLY

Gene Ontology

GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:1990108--P:protein linear deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001298	Ailuropoda melanoleuca	68.12	0.00e+00	1278.00
IUUC-Apl-003356	Anas platyrhynchos	68.74	0.00e+00	1258.00
IUUC-Aca-004402	Anolis carolinensis	64.04	0.00e+00	1114.00
IUUC-Ame-011581	Astyanax mexicanus	85.86	0.00e+00	1481.00
IUUC-Bta-012359	Bos taurus	68.12	0.00e+00	1273.00
IUUC-Cel-018528	Caenorhabditis elegans	31.52	4.00e-58	220.00
IUUC-Cja-018797	Callithrix jacchus	67.88	0.00e+00	1264.00
IUUC-Cfa-020264	Canis familiaris	67.91	0.00e+00	1274.00
IUUC-Cpo-022057	Cavia porcellus	68.22	0.00e+00	1275.00
IUUC-Csa-023093	Chlorocebus sabaeus	68.09	0.00e+00	1267.00
IUUC-Cho-024486	Choloepus hoffmanni	74.84	3.00e-134	473.00
IUUC-Cin-025179	Ciona intestinalis	44.53	2.00e-119	422.00
IUUC-Dre-028233	Danio rerio	83.77	0.00e+00	1517.00
IUUC-Dno-029496	Dasypus novemcinctus	68.26	0.00e+00	1274.00
IUUC-Dor-030919	Dipodomys ordii	64.94	0.00e+00	1207.00
IUUC-Dme-032159	Drosophila melanogaster	47.34	2.00e-125	443.00
IUUC-Ete-032734	Echinops telfairi	64.39	0.00e+00	1169.00
IUUC-Eca-033350	Equus caballus	68.12	0.00e+00	1277.00
IUUC-Eeu-034566	Erinaceus europaeus	77.42	3.00e-86	313.00
IUUC-Fca-035632	Felis catus	62.45	0.00e+00	796.00
IUUC-Fal-037313	Ficedula albicollis	65.10	0.00e+00	1172.00
IUUC-Gmo-039239	Gadus morhua	87.68	0.00e+00	1533.00
IUUC-Gga-040668	Gallus gallus	68.64	0.00e+00	1259.00
IUUC-Gac-042630	Gasterosteus aculeatus	90.17	0.00e+00	1575.00
IUUC-Ggo-044462	Gorilla gorilla	67.88	0.00e+00	1260.00
IUUC-Hsa-045846	Homo sapiens	67.88	0.00e+00	1261.00
IUUC-Itr-048894	Ictidomys tridecemlineatus	69.12	3.00e-161	561.00
IUUC-Lch-050303	Latimeria chalumnae	64.48	0.00e+00	1112.00
IUUC-Loc-052190	Lepisosteus oculatus	81.04	0.00e+00	1462.00
IUUC-Laf-054480	Loxodonta africana	76.94	0.00e+00	633.00
IUUC-Mcc-055849	Macaca mulatta	67.88	0.00e+00	1262.00
IUUC-Meu-056755	Macropus eugenii	56.19	4.00e-153	535.00
IUUC-Mga-059561	Meleagris gallopavo	68.01	0.00e+00	1247.00
IUUC-Mmr-060942	Microcebus murinus	68.01	0.00e+00	1261.00
IUUC-Mdo-062618	Monodelphis domestica	67.98	0.00e+00	1272.00
IUUC-Mmu-063843	Mus musculus	67.29	0.00e+00	1234.00
IUUC-Mpu-066919	Mustela putorius furo	68.22	0.00e+00	1281.00
IUUC-Mlu-066983	Myotis lucifugus	67.91	0.00e+00	1256.00
IUUC-Nle-069893	Nomascus leucogenys	67.98	0.00e+00	1261.00
IUUC-Opr-071181	Ochotona princeps	61.33	0.00e+00	1021.00
IUUC-Ont-071697	Oreochromis niloticus	92.57	0.00e+00	1568.00
IUUC-Oan-073658	Ornithorhynchus anatinus	68.05	0.00e+00	1259.00
IUUC-Ocu-074954	Oryctolagus cuniculus	68.43	0.00e+00	1272.00
IUUC-Ola-086523	Oryzias latipes	89.45	0.00e+00	1543.00
IUUC-Oga-089003	Otolemur garnettii	68.22	0.00e+00	1276.00
IUUC-Oar-090376	Ovis aries	67.84	0.00e+00	1273.00
IUUC-Ptr-090520	Pan troglodytes	66.32	0.00e+00	1214.00
IUUC-Pan-092281	Papio anubis	68.09	0.00e+00	1267.00
IUUC-Psi-093047	Pelodiscus sinensis	71.38	0.00e+00	1219.00
IUUC-Pma-094575	Petromyzon marinus	56.34	3.00e-66	244.00
IUUC-Pab-097740	Pongo abelii	67.77	0.00e+00	1259.00
IUUC-Pca-100461	Procavia capensis	60.99	0.00e+00	998.00
IUUC-Pva-102134	Pteropus vampyrus	61.80	0.00e+00	1114.00
IUUC-Rno-105807	Rattus norvegicus	67.19	0.00e+00	1220.00
IUUC-Sha-107236	Sarcophilus harrisii	67.97	0.00e+00	1239.00
IUUC-Sar-113366	Sorex araneus	81.78	0.00e+00	781.00
IUUC-Tgu-117201	Taeniopygia guttata	65.87	0.00e+00	1189.00
IUUC-Tru-117953	Takifugu rubripes	90.69	0.00e+00	1551.00
IUUC-Tsy-119610	Tarsius syrichta	66.25	0.00e+00	1228.00
IUUC-Tbe-128155	Tupaia belangeri	56.67	2.00e-148	520.00
IUUC-Ttr-128942	Tursiops truncatus	63.35	0.00e+00	1157.00
IUUC-Vpa-130281	Vicugna pacos	60.41	0.00e+00	1077.00
IUUC-Xtr-132627	Xenopus tropicalis	62.32	0.00e+00	1077.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence