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Tag Content
UUCD2 ID IUUC-Tgu-117201
UUCD1 version UUC-TaG-01023
Ensembl Protein ID ENSTGUP00000007768.1
UniProt Accession H0ZB11; H0ZB11_TAEGU
Genbank Protein ID ENSTGUP00000007768
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABQF01035818
Gene Name CYLD
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTGUG00000007517.1 ENSTGUT00000007850.1 ENSTGUP00000007768.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.60e-20 72.7 590 946
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp.kepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           G++ + N+CY++S+L cL++++++ + +l   ++++n+ ++ +e+++ l +++ + ++     + +k ++ r++l+++++++    ++e
   Q: 590  GIQGHYNSCYLDSTLFCLFSFSSVLDTVLL-RPKEMNDVEYySETQELLRTEIVNPLRIYGyVCATKIMKLRKILEKVEAASGF--TSE 675
           999***************************.666666665515555566678888888776899**************988875..899 PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk.sqikclecdnvssreepfldlslpv 176
           ++D +Efl++l++++ +       k ++  ++ +++   ++  +k++k +  +i++l+++++  s++k  e + +       l + +p+
   Q: 676  EKDPEEFLNILFHHILRVE--PLLKIRSAGQKVQDCYFYQIFMDKNEKVGVPTIQQLLEWSFInSNLKFAEVGDSCCLVRILLHFHIPF 762
           *****************99..88999999999999**************************8737899999999999999999999998 PP
   S: 177  pgkeetkkeslqdcL.esftkeeele.genkyycekckkkqeaekklklkklPe....vLilhLkRfsfseeqksrekinkkvefpleL 259
            ++++   ++ +     +  ++++++ g  +y+c++c+++++ +   k+k++++      +lh kR          ++ ++ +++p+ L
   Q: 763  VKNQSLPSLETNTFVaTAAPRQCRICrGLAMYECRECYEDTDISAG-KIKQFCKtcntQVHLHPKRQ---------SHKFNPLSLPKDL 841
           8888654444444444556666666526677**********85444.66666662223567777777.........3346778888665 PP
   S: 260  ...dlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk..WllfdD.............skVtevke.eevleetg.. 327
              d ++ c+        ++k eL+av++ +      HYva+vk  +++  Wl fd               +Vt+++e  e l+++   
   Q: 842  pdwDWRHGCIP-------SQKMELFAVLCIET----SHYVAFVKYGRDDsaWLFFDSmadrdggqngfniPQVTPCPEvGEYLKMSLee 919
           11144444555.......89*********999....9********66656799999999999999999997888886656777766577 PP
   S: 328  .................staYvlfYkr 337
                            ++aY+++Y++
   Q: 920  lhsldsrkiqgcarrllCDAYMCMYQS 946
           88888888888999***********85 PP
   
Organism Taeniopygia guttata
Protein Sequence
(Fasta)
MNSGLWSQEK ASSSYWEERI FYLLLQECSV IDKQTQKLLK VPKGSIGQFF QDRSSVAHSR 60
NIPCKGKKLQ IGLKILEQPH AVLFVDEKDV IEINEKLAEL LLAITNCEER YSLFKSKSRL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tgu-117201|DUB,USP|Taeniopygia guttata
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAATTCAG GCTTATGGAG TCAAGAAAAA GCAAGTTCAT CCTATTGGGA AGAGCGGATC 60
TTTTACTTGC TTCTCCAAGA ATGCAGTGTC ATAGACAAGC AGACTCAAAA GCTCTTGAAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tgu-117201|DUB,USP|Taeniopygia guttata
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR000938--CAP-Gly_domain
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50245--CAP_GLY_2
PS00972--USP_1
PS50235--USP_3
Pfam

PF01302--CAP_GLY
SMART

SM01052--CAP_GLY
Gene Ontology

GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0097542--C:ciliary tip
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0030496--C:midbody
GO:0005819--C:spindle
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0043369--P:CD4-positive or CD8-positive, alpha-beta T cell lineage commitment
GO:0048872--P:homeostasis of number of cells
GO:0045087--P:innate immune response
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0045581--P:negative regulation of T cell differentiation
GO:1903829--P:positive regulation of cellular protein localization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0045582--P:positive regulation of T cell differentiation
GO:0050862--P:positive regulation of T cell receptor signaling pathway
GO:1990108--P:protein linear deubiquitination
GO:0045577--P:regulation of B cell differentiation
GO:1902017--P:regulation of cilium assembly
GO:2001242--P:regulation of intrinsic apoptotic signaling pathway
GO:0070507--P:regulation of microtubule cytoskeleton organization
GO:0007346--P:regulation of mitotic cell cycle
GO:0043393--P:regulation of protein binding
GO:0010803--P:regulation of tumor necrosis factor-mediated signaling pathway
GO:1901026--P:ripoptosome assembly involved in necroptotic process
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001298 Ailuropoda melanoleuca 84.15 0.00e+00 1671.00
IUUC-Atr-003043 Amborella trichopoda 38.30 1.00e-01 30.00
IUUC-Apl-003356 Anas platyrhynchos 93.93 0.00e+00 1784.00
IUUC-Aca-004402 Anolis carolinensis 80.56 0.00e+00 1489.00
IUUC-Aly-005916 Arabidopsis lyrata 32.76 2.60e-02 32.00
IUUC-Ago-007723 Ashbya gossypii 37.78 3.90e-01 28.10
IUUC-Acl-008216 Aspergillus clavatus 47.22 2.00e-04 38.90
IUUC-Afl-008534 Aspergillus flavus 35.94 5.00e-05 40.80
IUUC-Afu-008927 Aspergillus fumigatus 35.82 2.00e-04 39.30
IUUC-Ani-009283 Aspergillus nidulans 40.91 4.00e-04 38.10
IUUC-Ang-009564 Aspergillus niger 41.82 4.00e-05 41.20
IUUC-Aor-010034 Aspergillus oryzae 35.94 5.00e-05 40.80
IUUC-Ate-010424 Aspergillus terreus 43.40 2.00e-04 39.30
IUUC-Ame-011581 Astyanax mexicanus 65.23 0.00e+00 1197.00
IUUC-Bta-012359 Bos taurus 84.31 0.00e+00 1669.00
IUUC-Bol-015891 Brassica oleracea 38.30 1.40e-01 29.30
IUUC-Cel-018528 Caenorhabditis elegans 33.68 2.00e-50 194.00
IUUC-Cja-018797 Callithrix jacchus 83.94 0.00e+00 1668.00
IUUC-Cfa-020264 Canis familiaris 84.52 0.00e+00 1675.00
IUUC-Cpo-022057 Cavia porcellus 83.94 0.00e+00 1669.00
IUUC-Cre-022753 Chlamydomonas reinhardtii 34.48 5.10e-02 31.20
IUUC-Csa-023093 Chlorocebus sabaeus 84.73 0.00e+00 1676.00
IUUC-Cho-024486 Choloepus hoffmanni 70.79 2.00e-153 536.00
IUUC-Cin-025179 Ciona intestinalis 40.62 1.00e-100 359.00
IUUC-Csv-025811 Ciona savignyi 36.54 1.00e-03 35.80
IUUC-Cne-026867 Cryptococcus neoformans 45.10 1.00e-06 46.20
IUUC-Cme-027227 Cyanidioschyzon merolae 38.18 3.70e-02 31.60
IUUC-Dre-028233 Danio rerio 65.60 0.00e+00 1228.00
IUUC-Dno-029496 Dasypus novemcinctus 84.10 0.00e+00 1672.00
IUUC-Dor-030919 Dipodomys ordii 79.14 0.00e+00 1543.00
IUUC-Dse-031240 Dothistroma septosporum 37.74 5.00e-04 37.40
IUUC-Dme-032159 Drosophila melanogaster 43.44 7.00e-107 380.00
IUUC-Ete-032734 Echinops telfairi 79.77 0.00e+00 1557.00
IUUC-Eca-033350 Equus caballus 84.62 0.00e+00 1682.00
IUUC-Eeu-034566 Erinaceus europaeus 88.71 5.00e-102 365.00
IUUC-Fca-035632 Felis catus 83.78 0.00e+00 1181.00
IUUC-Fal-037313 Ficedula albicollis 91.73 0.00e+00 1718.00
IUUC-Gmo-039239 Gadus morhua 65.18 0.00e+00 1176.00
IUUC-Ggr-039751 Gaeumannomyces graminis 34.92 2.40e-02 32.30
IUUC-Gga-040668 Gallus gallus 93.31 0.00e+00 1773.00
IUUC-Gac-042630 Gasterosteus aculeatus 65.56 0.00e+00 1182.00
IUUC-Gma-044336 Glycine max 31.82 3.00e-03 35.00
IUUC-Ggo-044462 Gorilla gorilla 84.25 0.00e+00 1670.00
IUUC-Hsa-045846 Homo sapiens 84.25 0.00e+00 1670.00
IUUC-Itr-048894 Ictidomys tridecemlineatus 85.15 0.00e+00 766.00
IUUC-Kpa-049126 Komagataella pastoris 38.46 5.00e-04 37.70
IUUC-Lch-050303 Latimeria chalumnae 71.96 0.00e+00 1331.00
IUUC-Loc-052190 Lepisosteus oculatus 67.56 0.00e+00 1218.00
IUUC-Lma-052977 Leptosphaeria maculans 42.11 5.00e-05 40.80
IUUC-Laf-054480 Loxodonta africana 82.79 0.00e+00 665.00
IUUC-Mcc-055849 Macaca mulatta 84.67 0.00e+00 1676.00
IUUC-Meu-056755 Macropus eugenii 76.22 0.00e+00 816.00
IUUC-Mpo-057404 Magnaporthe poae 31.51 3.60e-02 31.20
IUUC-Mtr-058357 Medicago truncatula 35.71 6.00e-03 33.90
IUUC-Mla-059125 Melampsora laricipopulina 34.72 1.00e-03 36.60
IUUC-Mga-059561 Meleagris gallopavo 92.60 0.00e+00 1761.00
IUUC-Mvi-060558 Microbotryum violaceum 36.67 4.00e-03 34.70
IUUC-Mmr-060942 Microcebus murinus 84.25 0.00e+00 1659.00
IUUC-Mdo-062618 Monodelphis domestica 84.05 0.00e+00 1665.00
IUUC-Mmu-063843 Mus musculus 82.69 0.00e+00 1595.00
IUUC-Mac-065590 Musa acuminata 32.76 3.00e-03 35.00
IUUC-Mpu-066919 Mustela putorius furo 84.41 0.00e+00 1674.00
IUUC-Mlu-066983 Myotis lucifugus 81.28 0.00e+00 1591.00
IUUC-Nfi-068351 Neosartorya fischeri 45.00 7.00e-04 37.40
IUUC-Ncr-068854 Neurospora crassa 28.28 2.00e-03 35.40
IUUC-Nle-069893 Nomascus leucogenys 84.36 0.00e+00 1671.00
IUUC-Opr-071181 Ochotona princeps 79.13 0.00e+00 1452.00
IUUC-Ont-071697 Oreochromis niloticus 64.56 0.00e+00 1167.00
IUUC-Oan-073658 Ornithorhynchus anatinus 83.89 0.00e+00 1635.00
IUUC-Ocu-074954 Oryctolagus cuniculus 84.57 0.00e+00 1677.00
IUUC-Ola-086523 Oryzias latipes 63.57 0.00e+00 1143.00
IUUC-Olu-087778 Ostreococcus lucimarinus 37.10 3.50e-02 31.60
IUUC-Oga-089003 Otolemur garnettii 84.57 0.00e+00 1682.00
IUUC-Oar-090376 Ovis aries 83.90 0.00e+00 1671.00
IUUC-Ptr-090520 Pan troglodytes 82.48 0.00e+00 1620.00
IUUC-Pan-092281 Papio anubis 84.73 0.00e+00 1676.00
IUUC-Psi-093047 Pelodiscus sinensis 90.54 0.00e+00 1623.00
IUUC-Pma-094575 Petromyzon marinus 54.79 1.00e-66 245.00
IUUC-Pno-094999 Phaeosphaeria nodorum 34.72 4.00e-04 37.70
IUUC-Pfo-096358 Poecilia formosa 64.96 0.00e+00 1124.00
IUUC-Pab-097740 Pongo abelii 84.05 0.00e+00 1664.00
IUUC-Pop-099133 Populus trichocarpa 32.79 1.60e-01 29.30
IUUC-Pca-100461 Procavia capensis 74.61 0.00e+00 1313.00
IUUC-Ppe-101764 Prunus persica 37.70 5.00e-03 34.30
IUUC-Pva-102134 Pteropus vampyrus 75.50 0.00e+00 1464.00
IUUC-Pgr-103337 Puccinia graminis 33.93 4.00e-08 51.20
IUUC-Ptt-103764 Puccinia triticina 51.52 1.00e-04 40.00
IUUC-Pte-104265 Pyrenophora teres 33.33 4.00e-04 37.70
IUUC-Pyt-104528 Pyrenophora triticirepentis 33.33 2.00e-04 39.30
IUUC-Rno-105807 Rattus norvegicus 81.69 0.00e+00 1567.00
IUUC-Sha-107236 Sarcophilus harrisii 84.45 0.00e+00 1612.00
IUUC-Sja-107978 Schizosaccharomyces japonicus 50.00 3.00e-09 55.10
IUUC-Spo-108310 Schizosaccharomyces pombe 41.51 2.00e-05 42.00
IUUC-Sly-111811 Solanum lycopersicum 37.10 9.00e-03 33.50
IUUC-Stu-111984 Solanum tuberosum 37.10 1.10e-02 33.10
IUUC-Sar-113366 Sorex araneus 88.94 0.00e+00 837.00
IUUC-Sre-115083 Sporisorium reilianum 36.84 8.00e-04 37.00
IUUC-Ssc-116306 Sus scrofa 29.63 1.00e-03 36.20
IUUC-Tru-117953 Takifugu rubripes 65.52 0.00e+00 1165.00
IUUC-Tsy-119610 Tarsius syrichta 82.17 0.00e+00 1625.00
IUUC-Tni-120743 Tetraodon nigroviridis 38.52 4.00e-152 531.00
IUUC-Tca-121819 Theobroma cacao 36.84 4.00e-03 34.70
IUUC-Tme-127153 Tuber melanosporum 34.04 3.00e-04 38.50
IUUC-Tbe-128155 Tupaia belangeri 75.58 7.00e-180 624.00
IUUC-Ttr-128942 Tursiops truncatus 78.94 0.00e+00 1548.00
IUUC-Uma-129608 Ustilago maydis 23.96 5.00e-05 40.80
IUUC-Vda-129806 Verticillium dahliae 32.88 2.00e-03 35.40
IUUC-Vpa-130281 Vicugna pacos 74.63 0.00e+00 1429.00
IUUC-Vvi-131178 Vitis vinifera 37.70 6.00e-03 33.90
IUUC-Xtr-132627 Xenopus tropicalis 75.18 0.00e+00 1367.00
IUUC-Xma-133449 Xiphophorus maculatus 63.66 0.00e+00 1087.00
IUUC-Yli-134439 Yarrowia lipolytica 47.17 4.00e-06 44.70
Created Date 25-Jun-2017

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