iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000078926.8	ENSMUST00000180543.7	ENSMUSP00000137651.1
ENSMUSG00000078926.8	ENSMUST00000181568.7	ENSMUSP00000137849.1
ENSMUSG00000078926.8	ENSMUST00000109244.8	ENSMUSP00000104867.1
ENSMUSG00000078926.8	ENSMUST00000181117.7	ENSMUSP00000137915.1
ENSMUSG00000078926.8	ENSMUST00000181741.1	ENSMUSP00000137759.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.70e-15	55.7	354	382

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvW 28
           H++ v++l++ +d +ll+sG++Dg + +W
   Q: 354  HKEAVCSLKWsPDgRLLSSGCNDGLLTIW 382
           9999*******99999************* PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MEWKLQRTAR RKIRTEEEML WENIMRVLAN GMKQQRNQGS PKELDSVAVT YSSFKSNFVK 60
RLSAEIPVAS SPITTRWQLS PARDPESSSS VEEGPPSHTP ESLASGLKIT PAADTLTLRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACACCCCAG ACTTGACGTC ATCGAGGCGC TGGCCTGTGG CGGGACCGAC GGAAGGAGGT 60
TCCCGCTTTG ATTGCCGCCC CGCGGGCTTT TTAAAGGTTA CCCTGGGGAA TACGCTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

mmu:238896

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001252	Ailuropoda melanoleuca	71.10	0.00e+00	758.00
IUUC-Aca-004279	Anolis carolinensis	42.62	1.00e-116	413.00
IUUC-Bta-012666	Bos taurus	67.57	3.00e-175	608.00
IUUC-Cja-019214	Callithrix jacchus	71.48	0.00e+00	756.00
IUUC-Cfa-021220	Canis familiaris	67.58	0.00e+00	654.00
IUUC-Cpo-021553	Cavia porcellus	69.94	0.00e+00	729.00
IUUC-Csa-024185	Chlorocebus sabaeus	71.29	0.00e+00	712.00
IUUC-Cho-025064	Choloepus hoffmanni	54.04	1.00e-150	526.00
IUUC-Dno-029229	Dasypus novemcinctus	68.83	0.00e+00	680.00
IUUC-Dor-030414	Dipodomys ordii	78.50	7.00e-140	490.00
IUUC-Eca-033225	Equus caballus	72.61	0.00e+00	772.00
IUUC-Eeu-035215	Erinaceus europaeus	66.12	0.00e+00	642.00
IUUC-Fca-036143	Felis catus	71.92	0.00e+00	773.00
IUUC-Gga-040300	Gallus gallus	48.27	9.00e-117	413.00
IUUC-Ggo-045256	Gorilla gorilla	72.25	0.00e+00	683.00
IUUC-Hsa-045939	Homo sapiens	72.25	0.00e+00	743.00
IUUC-Lch-050132	Latimeria chalumnae	54.68	2.00e-88	318.00
IUUC-Loc-051872	Lepisosteus oculatus	40.45	6.00e-106	377.00
IUUC-Laf-053539	Loxodonta africana	69.88	0.00e+00	701.00
IUUC-Mcc-054908	Macaca mulatta	71.68	0.00e+00	720.00
IUUC-Meu-056429	Macropus eugenii	53.05	4.00e-89	322.00
IUUC-Mga-060081	Meleagris gallopavo	56.77	6.00e-97	347.00
IUUC-Mmr-060846	Microcebus murinus	71.18	0.00e+00	721.00
IUUC-Mdo-062147	Monodelphis domestica	54.89	4.00e-162	564.00
IUUC-Nle-069735	Nomascus leucogenys	68.42	1.00e-171	596.00
IUUC-Ocu-074439	Oryctolagus cuniculus	69.98	0.00e+00	681.00
IUUC-Oga-088043	Otolemur garnettii	72.27	0.00e+00	657.00
IUUC-Oar-089869	Ovis aries	67.27	0.00e+00	665.00
IUUC-Ptr-090818	Pan troglodytes	72.25	0.00e+00	747.00
IUUC-Pan-092774	Papio anubis	71.11	0.00e+00	692.00
IUUC-Psi-093250	Pelodiscus sinensis	50.56	6.00e-150	524.00
IUUC-Pab-098227	Pongo abelii	71.48	0.00e+00	728.00
IUUC-Pva-103255	Pteropus vampyrus	71.15	0.00e+00	761.00
IUUC-Sha-107377	Sarcophilus harrisii	51.57	2.00e-131	462.00
IUUC-Ssc-115477	Sus scrofa	65.45	0.00e+00	659.00
IUUC-Tsy-118931	Tarsius syrichta	73.41	0.00e+00	756.00
IUUC-Tbe-127532	Tupaia belangeri	60.36	2.00e-104	373.00
IUUC-Ttr-128250	Tursiops truncatus	70.85	1.00e-168	586.00
IUUC-Vpa-130775	Vicugna pacos	71.79	1.00e-173	602.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence