iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035485

Ensembl Protein ID

ENSFCAP00000025404.1

UniProt Accession

M3XFJ3; M3XFJ3_FELCA

Genbank Protein ID

ENSFCAP00000025404

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02005709

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000031344.1	ENSFCAT00000023017.1	ENSFCAP00000025404.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-35	119.2	118	155
UBD/Beta-Prp	3.10e-55	187.5	220	477

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 118  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 155
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 220  QRYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 308
           689*****************99999988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 309  QFCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrvsgdlsleEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 397
           **************************99998999*********98877778889*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 398  LLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 477
           **9.*********555555..99****************999977766544444456677789999*****999999998886 PP

Organism

Felis catus

Protein Sequence
(Fasta)

VLSNKHVAPD HLLQICQRIG PMLDKEIPPS ISRVTSLLGA GRQSLLRTAK DCRHTVWKGS 60
AFAALHRGRP PEMPVNYGSP PSLVEIHRGK QLTGCSTFST AFPGTMYQHI KMHRRILGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNT GGGAGGGCAA CGAGCACAAC AGGAGCTACG AGGAATTGGT 60
GAGATTTTTG ACATTTCTAT CCCCGTGTTT CCGAACATCC TCTCCCCGCC CCCTTGTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002332	Ailuropoda melanoleuca	93.15	0.00e+00	3125.00
IUUC-Bta-013217	Bos taurus	82.85	0.00e+00	3101.00
IUUC-Bol-015737	Brassica oleracea	31.55	1.00e-68	255.00
IUUC-Bra-017961	Brassica rapa	31.68	2.00e-68	254.00
IUUC-Cja-019966	Callithrix jacchus	82.59	0.00e+00	3129.00
IUUC-Cfa-021037	Canis familiaris	92.46	0.00e+00	3200.00
IUUC-Cpo-021934	Cavia porcellus	90.13	0.00e+00	2593.00
IUUC-Csa-023352	Chlorocebus sabaeus	82.11	0.00e+00	2920.00
IUUC-Cho-024690	Choloepus hoffmanni	67.30	0.00e+00	907.00
IUUC-Dno-028938	Dasypus novemcinctus	80.50	0.00e+00	3046.00
IUUC-Eca-034349	Equus caballus	83.79	0.00e+00	3032.00
IUUC-Gma-044324	Glycine max	31.08	6.00e-64	240.00
IUUC-Ggo-045500	Gorilla gorilla	82.98	0.00e+00	3080.00
IUUC-Hsa-046350	Homo sapiens	82.75	0.00e+00	3082.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	95.08	0.00e+00	1128.00
IUUC-Lch-049662	Latimeria chalumnae	79.97	0.00e+00	1228.00
IUUC-Laf-053848	Loxodonta africana	80.97	0.00e+00	3059.00
IUUC-Mcc-054638	Macaca mulatta	82.71	0.00e+00	3070.00
IUUC-Meu-056739	Macropus eugenii	79.65	0.00e+00	1105.00
IUUC-Mmr-061227	Microcebus murinus	82.51	0.00e+00	3088.00
IUUC-Mdo-062074	Monodelphis domestica	89.92	0.00e+00	1358.00
IUUC-Mmu-064075	Mus musculus	81.55	0.00e+00	2846.00
IUUC-Mpu-066643	Mustela putorius furo	92.79	0.00e+00	3045.00
IUUC-Mlu-067735	Myotis lucifugus	85.49	0.00e+00	3057.00
IUUC-Nle-069402	Nomascus leucogenys	90.35	0.00e+00	2840.00
IUUC-Oan-072954	Ornithorhynchus anatinus	74.83	0.00e+00	2562.00
IUUC-Ogl-077493	Oryza glaberrima	27.29	2.00e-29	125.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.06	9.00e-56	212.00
IUUC-Oga-087938	Otolemur garnettii	78.18	0.00e+00	2780.00
IUUC-Oar-090214	Ovis aries	82.91	0.00e+00	3096.00
IUUC-Ptr-091213	Pan troglodytes	82.85	0.00e+00	3044.00
IUUC-Pan-092444	Papio anubis	82.33	0.00e+00	3059.00
IUUC-Pfo-097318	Poecilia formosa	61.99	0.00e+00	1691.00
IUUC-Pab-097573	Pongo abelii	81.54	0.00e+00	2976.00
IUUC-Pva-102782	Pteropus vampyrus	82.71	0.00e+00	3156.00
IUUC-Rno-105687	Rattus norvegicus	81.12	0.00e+00	2855.00
IUUC-Sha-106680	Sarcophilus harrisii	89.18	0.00e+00	1357.00
IUUC-Sar-113519	Sorex araneus	79.81	0.00e+00	1731.00
IUUC-Tsy-118921	Tarsius syrichta	86.80	0.00e+00	1884.00
IUUC-Tbe-127663	Tupaia belangeri	77.23	0.00e+00	850.00
IUUC-Ttr-128561	Tursiops truncatus	83.89	0.00e+00	2898.00
IUUC-Vpa-130444	Vicugna pacos	79.92	0.00e+00	2843.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence