iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133935

Ensembl Protein ID

ENSXMAP00000001722.1

UniProt Accession

M3ZHN0; M3ZHN0_XIPMA

Genbank Protein ID

ENSXMAP00000001722

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01008198

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000001721.1	ENSXMAT00000001726.1	ENSXMAP00000001722.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.40e-25	87.6	430	498
E3 adaptor/Cullin RING/DCX/DWD	1.00e-33	113.9	236	273
UBD/Beta-Prp	7.70e-51	173.1	6	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawce 70
           vp+eflCpI+ elMr+Pv++++G++y+r++Ie w+ ++++++P+t+ pl  + l+Pn+tl+  i++w  
   Q: 430  VPDEFLCPITRELMREPVIAADGYSYERQAIENWIHTKNRSSPMTNLPLLTTLLTPNHTLKMAISRWKT 498
           8******************************************************************76 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           g+t++v+c+a+ sd  llvsGs D++ikv+D    vll
   Q: 236  GQTAPVFCCAYsSDgQLLVSGSVDKSIKVYDANNAVLL 273
           6799********999****************7766666 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvht 89
           +tl++h+++ i+  +f  + +llat s d+t++++++++ +   ++ l+gh+  v +++fsp g++l+++s+D+t  vw++ tg +  +
   Q: 6    CTLRDHQDD-INWCAF--SAKLLATCSGDKTLRIYNAEDFSElpFSPLKGHSYSVHCCCFSPCGQFLISCSTDATTLVWSMVTGGIEAV 91
           778888775.566889..9********************777899******************************************99 PP
   S: 90   lkghed..svlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           l+ h d   v+ +++sp+  +lvsG +d t+ vwd +++  ++ t  ++d +    +++p ++++++Gs+ + +rlWdl  ++ll +  
   Q: 92   LE-HPDrsPVRICALSPNAAHLVSGASDGTLAVWDFHSKRLSR-TGGVRDTTMVACSFSPCSQMFMTGSTYGDLRLWDLHLNQLLAKKD 178
           99.544126*********************************9.999999999999999999*************************98 PP
   S: 177  gghtdsvyslsfdsng........kelvsgsldgtvklwdlq 210
             h+  v + sf ++         ++l+s+++d  +k+w + 
   Q: 179  A-HDLGVSCCSFAPSIlsgnqvvqFHLASCGQDCHLKIWVIN 219
           7.*********8886677788******************775 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MASVVCTLRD HQDDINWCAF SAKLLATCSG DKTLRIYNAE DFSELPFSPL KGHSYSVHCC 60
CFSPCGQFLI SCSTDATTLV WSMVTGGIEA VLEHPDRSPV RICALSPNAA HLVSGASDGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGAACAGA GAGGAAGTAA ACAGTGAATA ACAGAGACGG ACAGAGACGA GTAAGATTGA 60
CGTTGTTCAA CAATACCAGA TGCTGCAGGA CGCGGTCTAC TGACTAGTCT TTTTTCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004257	Anolis carolinensis	50.88	2.00e-138	485.00
IUUC-Ame-011357	Astyanax mexicanus	55.18	2.00e-143	501.00
IUUC-Bta-013032	Bos taurus	53.40	2.00e-144	506.00
IUUC-Csa-023954	Chlorocebus sabaeus	54.40	3.00e-145	508.00
IUUC-Dre-028087	Danio rerio	64.74	7.00e-179	620.00
IUUC-Dno-028919	Dasypus novemcinctus	54.20	5.00e-145	507.00
IUUC-Dor-031112	Dipodomys ordii	53.80	7.00e-143	500.00
IUUC-Eca-033254	Equus caballus	53.29	2.00e-145	508.00
IUUC-Eeu-034545	Erinaceus europaeus	53.29	2.00e-136	478.00
IUUC-Gmo-039213	Gadus morhua	63.47	4.00e-176	610.00
IUUC-Gac-041471	Gasterosteus aculeatus	75.45	0.00e+00	695.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	49.88	4.00e-106	377.00
IUUC-Loc-052307	Lepisosteus oculatus	63.49	0.00e+00	642.00
IUUC-Laf-053587	Loxodonta africana	55.00	1.00e-146	513.00
IUUC-Mmr-060943	Microcebus murinus	52.39	3.00e-136	478.00
IUUC-Mdo-062592	Monodelphis domestica	53.20	3.00e-143	501.00
IUUC-Mmu-063577	Mus musculus	52.69	1.00e-142	499.00
IUUC-Nle-069517	Nomascus leucogenys	54.00	2.00e-144	505.00
IUUC-Opr-070776	Ochotona princeps	54.17	9.00e-146	509.00
IUUC-Ont-071821	Oreochromis niloticus	75.75	0.00e+00	749.00
IUUC-Oan-073706	Ornithorhynchus anatinus	53.17	9.00e-145	506.00
IUUC-Ocu-074766	Oryctolagus cuniculus	49.60	3.00e-125	441.00
IUUC-Ola-086531	Oryzias latipes	77.20	0.00e+00	735.00
IUUC-Oar-089748	Ovis aries	53.40	7.00e-146	510.00
IUUC-Psi-093334	Pelodiscus sinensis	52.58	9.00e-129	453.00
IUUC-Pma-094383	Petromyzon marinus	42.75	2.00e-107	382.00
IUUC-Pfo-096801	Poecilia formosa	88.45	0.00e+00	857.00
IUUC-Pca-100523	Procavia capensis	52.27	3.00e-90	325.00
IUUC-Rno-104831	Rattus norvegicus	52.19	2.00e-142	498.00
IUUC-Sha-107499	Sarcophilus harrisii	53.80	1.00e-143	503.00
IUUC-Sar-113389	Sorex araneus	52.80	3.00e-139	488.00
IUUC-Tru-118774	Takifugu rubripes	72.20	0.00e+00	680.00
IUUC-Tni-119850	Tetraodon nigroviridis	71.77	0.00e+00	711.00
IUUC-Tbe-127938	Tupaia belangeri	46.71	3.00e-78	285.00
IUUC-Ttr-128193	Tursiops truncatus	51.76	6.00e-121	427.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence