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Tag Content
iUUCD ID IUUC-Pan-092150
Ensembl Protein ID ENSPANP00000004094.1
UniProt Accession A0A096MW53; A0A096MW53_PAPAN
Genbank Protein ID ENSPANP00000004094
Protein Name Uncharacterized protein
Genbank Nucleotide ID AHZZ01017324
Gene Name VHL
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPANG00000026095.1 ENSPANT00000026128.1 ENSPANP00000004094.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box 26.72 2.00e-03 39.30 IUUC-Dme-031988
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box 95.77 5.00e-86 314.00 IUUC-Hsa-046547
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Papio anubis
Protein Sequence
(Fasta)
MPRRAENWDE AEAGAEEAGA EEYGPEEGGR EESGAEESGP EESGPEELGA EEEMEAGRPL 60
PVLRSVNSRE PSQVIFCNRS PRVVLPLWLN FDGEPQPYPT LPPGTGRRIH SYRGHLWLFR 120
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Protein Fasta Sequence



>IUUC-Pan-092150|E3,SOCS|Papio anubis
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Nucleotide Sequence
(Fasta)
CGCGCACAGC CTCTGGCCGG CTATGTCCTC GAGCGGGTTC CATCCTCTAC CCAGCGCGCG 60
CGAAGGCTAC GCAGGTCGAC TCGGGAGCGC GCACGCAACT CCGCCTCGCG TCCGGCCCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Pan-092150|E3,SOCS|Papio anubis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002714--VHL
IPR024048--VHL_alpha_dom
IPR024053--VHL_beta_dom
IPR022772--VHL_tumour_suppress_b/a_dom

Pfam

PF01847--VHL
PF17211--VHL_C

Gene Ontology

GO:0005929--C:cilium
GO:0031462--C:Cul2-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0061630--F:ubiquitin protein ligase activity
GO:0001525--P:angiogenesis
GO:0043534--P:blood vessel endothelial cell migration
GO:0061073--P:ciliary body morphogenesis
GO:0030198--P:extracellular matrix organization
GO:0048069--P:eye pigmentation
GO:0048877--P:homeostasis of number of retina cells
GO:0061072--P:iris morphogenesis
GO:0006582--P:melanin metabolic process
GO:0045602--P:negative regulation of endothelial cell differentiation
GO:1902072--P:negative regulation of hypoxia-inducible factor-1alpha signaling pathway
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0061428--P:negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0006607--P:NLS-bearing protein import into nucleus
GO:0003310--P:pancreatic A cell differentiation
GO:0050679--P:positive regulation of epithelial cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0010498--P:proteasomal protein catabolic process
GO:2001233--P:regulation of apoptotic signaling pathway
GO:1903827--P:regulation of cellular protein localization
GO:0003309--P:type B pancreatic cell differentiation

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002327 Ailuropoda melanoleuca 83.77 5.00e-68 250.00
IUUC-Apl-003580 Anas platyrhynchos 69.74 3.00e-25 105.00
IUUC-Aca-004492 Anolis carolinensis 77.17 6.00e-56 209.00
IUUC-Ang-009806 Aspergillus niger 40.62 1.80e-01 26.90
IUUC-Ame-011818 Astyanax mexicanus 56.25 4.00e-44 171.00
IUUC-Bta-013459 Bos taurus 92.99 5.00e-83 300.00
IUUC-Cel-018173 Caenorhabditis elegans 31.48 3.00e-05 41.60
IUUC-Cja-019826 Callithrix jacchus 96.82 7.00e-86 309.00
IUUC-Cfa-021280 Canis familiaris 94.16 6.00e-82 296.00
IUUC-Cpo-022544 Cavia porcellus 83.70 9.00e-84 301.00
IUUC-Cre-022809 Chlamydomonas reinhardtii 43.33 3.00e-08 53.10
IUUC-Csa-023644 Chlorocebus sabaeus 99.37 1.00e-90 325.00
IUUC-Cho-024479 Choloepus hoffmanni 65.15 6.00e-42 162.00
IUUC-Cin-025505 Ciona intestinalis 27.68 2.00e-05 41.60
IUUC-Cgl-026420 Colletotrichum gloeosporioides 31.43 5.90e+00 25.80
IUUC-Cme-027232 Cyanidioschyzon merolae 32.43 1.00e-05 42.70
IUUC-Dre-028350 Danio rerio 53.42 2.00e-33 135.00
IUUC-Dno-029207 Dasypus novemcinctus 87.96 1.00e-51 195.00
IUUC-Dor-030912 Dipodomys ordii 66.45 8.00e-51 192.00
IUUC-Dme-031988 Drosophila melanogaster 26.72 5.00e-05 40.80
IUUC-Eca-034007 Equus caballus 97.50 1.00e-18 84.00
IUUC-Fca-036350 Felis catus 93.59 3.00e-81 294.00
IUUC-Fal-037192 Ficedula albicollis 67.79 3.00e-54 204.00
IUUC-Gmo-038921 Gadus morhua 58.39 3.00e-44 171.00
IUUC-Gga-041016 Gallus gallus 69.72 2.00e-54 204.00
IUUC-Gac-042560 Gasterosteus aculeatus 52.08 4.00e-36 144.00
IUUC-Ggo-045419 Gorilla gorilla 94.84 1.00e-85 308.00
IUUC-Hsa-046547 Homo sapiens 95.77 3.00e-86 310.00
IUUC-Itr-048225 Ictidomys tridecemlineatus 94.87 2.00e-84 304.00
IUUC-Lch-050463 Latimeria chalumnae 62.34 5.00e-53 200.00
IUUC-Loc-052053 Lepisosteus oculatus 56.34 3.00e-46 177.00
IUUC-Laf-053893 Loxodonta africana 91.14 4.00e-82 296.00
IUUC-Mcc-055347 Macaca mulatta 63.43 9.00e-63 232.00
IUUC-Mtr-058490 Medicago truncatula 48.48 9.00e-03 33.50
IUUC-Mdo-062169 Monodelphis domestica 75.53 6.00e-38 148.00
IUUC-Mmu-064366 Mus musculus 94.96 4.00e-75 273.00
IUUC-Mpu-066593 Mustela putorius furo 92.95 2.00e-82 298.00
IUUC-Mlu-066926 Myotis lucifugus 89.19 9.00e-86 308.00
IUUC-Nle-069724 Nomascus leucogenys 96.24 5.00e-87 313.00
IUUC-Opr-070679 Ochotona princeps 79.55 9.00e-77 278.00
IUUC-Ont-071332 Oreochromis niloticus 52.56 4.00e-42 163.00
IUUC-Ola-086869 Oryzias latipes 50.64 2.00e-40 158.00
IUUC-Oga-089124 Otolemur garnettii 94.34 2.00e-83 301.00
IUUC-Oar-089799 Ovis aries 91.92 4.00e-50 188.00
IUUC-Ptr-091186 Pan troglodytes 96.04 1.00e-52 197.00
IUUC-Psi-094039 Pelodiscus sinensis 66.43 4.00e-51 193.00
IUUC-Pma-094129 Petromyzon marinus 44.76 4.00e-28 117.00
IUUC-Pfo-096892 Poecilia formosa 51.39 2.00e-37 147.00
IUUC-Pab-097822 Pongo abelii 97.44 2.00e-86 311.00
IUUC-Pca-101058 Procavia capensis 83.26 3.00e-78 284.00
IUUC-Pva-102932 Pteropus vampyrus 96.20 1.00e-86 311.00
IUUC-Rno-105050 Rattus norvegicus 93.67 1.00e-85 308.00
IUUC-Sha-106738 Sarcophilus harrisii 78.00 8.00e-43 164.00
IUUC-Ssc-115973 Sus scrofa 92.36 1.00e-82 298.00
IUUC-Tgu-116663 Taeniopygia guttata 72.53 2.00e-33 132.00
IUUC-Tru-118654 Takifugu rubripes 56.25 2.00e-42 164.00
IUUC-Tca-121306 Theobroma cacao 38.89 3.60e-02 29.60
IUUC-Ttr-128418 Tursiops truncatus 93.67 1.00e-84 305.00
IUUC-Vpa-130268 Vicugna pacos 90.91 2.00e-47 181.00
IUUC-Xtr-132506 Xenopus tropicalis 65.03 4.00e-54 203.00
Created Date 25-Jun-2017

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