iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091685

Ensembl Protein ID

ENSPANP00000006109.1

UniProt Accession

A0A096N1E1; A0A096N1E1_PAPAN

Genbank Protein ID

ENSPANP00000006109

Protein Name

Probable cytosolic iron-sulfur protein assembly protein CIAO1; WD repeat-containing protein 39

Genbank Nucleotide ID

AHZZ01038020

Gene Name

CIAO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000022838.1	ENSPANT00000028040.1	ENSPANP00000006109.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-42	141.0	439	469
UBD/Beta-Prp	2.10e-60	204.5	260	468

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH++ v++laf ++  +l+s+sdD t+++W+
   Q: 439  GHESTVWSLAFdPSgQRLASCSDDRTVRIWR 469
           8***********6669**************8 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrsl.sgheaevtavkfspdgkilvtgseDrtikvw..dlstgkcvhtl 90
           +h++s++  +++ p ++lla+ + d++i++w ++  +    + l +gh+ +v+ v +sp g++l+++s D+t ++w  + ++++cv tl
   Q: 260  AHPDSRCWFLAWNPAGTLLASCGGDRRIRIWGTEGDSWicKSVLsEGHQRTVRKVAWSPCGNYLASASFDATTCIWkkNQDDFECVTTL 348
           688999999999*********************9877654566689******************************99999******** PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk..llrtl 175
           +ghe++v s+++ psg+ l++ s+d+ + vw+++++ ++e   +l+ h++ v +vv+hp++ ll+s+s+D tv+l++ + ++  +  tl
   Q: 349  EGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECvsVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDwvCCATL 437
           *********************************9987776566*********************************9977754499*** PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklw 207
           +g h++ v sl+fd++g++l+s+s+d+tv++w
   Q: 438  EG-HESTVWSLAFDPSGQRLASCSDDRTVRIW 468
           *9.***************************** PP

Organism

Papio anubis

Functional Description
(View)

Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

Protein Sequence
(Fasta)

MGLRDENWTG PGARWGLGRL ESPGGGGIGD WLPREQRPGL RVSARGCRGA EDRAGPRGSG 60
NGDLGPAVCD ATCAEKRPSP RRPLFLTSQQ ATGLGWRRSA QSRASRLPGA ERSQAPIPQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGACTGC GGGACGAAAA CTGGACAGGG CCAGGGGCCA GATGGGGTCT GGGCAGACTC 60
GAGTCCCCGG GGGGCGGAGG GATCGGGGAT TGGCTACCGC GGGAGCAAAG ACCCGGACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR028608--CIAO1/Cia1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097361--C:CIA complex
GO:0071817--C:MMXD complex
GO:0007059--P:chromosome segregation
GO:0016226--P:iron-sulfur cluster assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000874	Aegilops tauschii	48.00	1.00e-67	251.00
IUUC-Aml-001317	Ailuropoda melanoleuca	96.76	0.00e+00	640.00
IUUC-Atr-003029	Amborella trichopoda	51.61	1.00e-95	342.00
IUUC-Apl-004042	Anas platyrhynchos	76.52	3.00e-57	213.00
IUUC-Aly-006458	Arabidopsis lyrata	48.41	3.00e-87	315.00
IUUC-Ath-006671	Arabidopsis thaliana	48.41	4.00e-87	314.00
IUUC-Ago-007820	Ashbya gossypii	40.35	2.00e-60	225.00
IUUC-Acl-008042	Aspergillus clavatus	31.57	1.00e-50	194.00
IUUC-Afl-008639	Aspergillus flavus	32.38	9.00e-53	201.00
IUUC-Afu-008899	Aspergillus fumigatus	35.51	5.00e-49	188.00
IUUC-Ani-009453	Aspergillus nidulans	32.38	5.00e-51	195.00
IUUC-Ang-009758	Aspergillus niger	34.23	4.00e-51	195.00
IUUC-Aor-010212	Aspergillus oryzae	32.38	9.00e-53	201.00
IUUC-Ate-010314	Aspergillus terreus	32.61	3.00e-52	199.00
IUUC-Ame-010676	Astyanax mexicanus	77.25	1.00e-159	555.00
IUUC-Bgr-012095	Blumeria graminis	30.46	6.00e-38	151.00
IUUC-Bta-012884	Bos taurus	93.51	2.00e-178	618.00
IUUC-Bci-013622	Botrytis cinerea	30.34	2.00e-37	149.00
IUUC-Bdi-014614	Brachypodium distachyon	48.82	1.00e-86	312.00
IUUC-Bol-016439	Brassica oleracea	47.35	3.00e-84	305.00
IUUC-Bra-016830	Brassica rapa	46.61	4.00e-83	301.00
IUUC-Cel-018709	Caenorhabditis elegans	40.12	3.00e-63	235.00
IUUC-Cja-019822	Callithrix jacchus	98.53	0.00e+00	652.00
IUUC-Cfa-020823	Canis familiaris	97.35	0.00e+00	642.00
IUUC-Cre-022811	Chlamydomonas reinhardtii	47.67	9.00e-81	293.00
IUUC-Csa-023754	Chlorocebus sabaeus	100.00	0.00e+00	659.00
IUUC-Cin-025395	Ciona intestinalis	57.31	2.00e-117	415.00
IUUC-Csv-025943	Ciona savignyi	55.39	2.00e-113	401.00
IUUC-Cgl-026435	Colletotrichum gloeosporioides	33.67	8.00e-37	147.00
IUUC-Cne-026939	Cryptococcus neoformans	32.43	3.00e-49	189.00
IUUC-Cme-027239	Cyanidioschyzon merolae	41.35	4.00e-45	175.00
IUUC-Dre-028172	Danio rerio	76.95	7.00e-158	549.00
IUUC-Dno-029472	Dasypus novemcinctus	95.56	8.00e-155	539.00
IUUC-Dor-031134	Dipodomys ordii	85.25	1.00e-154	538.00
IUUC-Dse-031535	Dothistroma septosporum	30.33	2.00e-46	179.00
IUUC-Dme-032020	Drosophila melanogaster	59.09	8.00e-119	419.00
IUUC-Eca-033700	Equus caballus	97.94	0.00e+00	645.00
IUUC-Eeu-035010	Erinaceus europaeus	94.40	6.00e-179	619.00
IUUC-Fca-036309	Felis catus	88.82	2.00e-173	601.00
IUUC-Fal-037243	Ficedula albicollis	73.95	3.00e-86	310.00
IUUC-Fox-038058	Fusarium oxysporum	31.82	6.00e-45	175.00
IUUC-Fso-038459	Fusarium solani	35.43	6.00e-40	158.00
IUUC-Gmo-039375	Gadus morhua	75.52	2.00e-142	498.00
IUUC-Ggr-040002	Gaeumannomyces graminis	35.39	2.00e-41	163.00
IUUC-Gga-040294	Gallus gallus	83.39	5.00e-131	460.00
IUUC-Gac-042499	Gasterosteus aculeatus	74.78	8.00e-140	489.00
IUUC-Gma-043543	Glycine max	48.97	3.00e-88	318.00
IUUC-Ggo-045181	Gorilla gorilla	100.00	0.00e+00	659.00
IUUC-Hsa-046528	Homo sapiens	100.00	0.00e+00	659.00
IUUC-Hvu-047341	Hordeum vulgare	57.45	3.00e-56	211.00
IUUC-Itr-048790	Ictidomys tridecemlineatus	97.94	0.00e+00	645.00
IUUC-Kpa-049353	Komagataella pastoris	37.82	7.00e-58	217.00
IUUC-Lch-049763	Latimeria chalumnae	80.24	1.00e-162	565.00
IUUC-Lpe-051500	Leersia perrieri	44.74	3.00e-82	298.00
IUUC-Loc-052021	Lepisosteus oculatus	80.54	9.00e-155	539.00
IUUC-Lma-053331	Leptosphaeria maculans	35.00	1.00e-56	214.00
IUUC-Laf-054558	Loxodonta africana	95.28	0.00e+00	629.00
IUUC-Mcc-055374	Macaca mulatta	99.71	0.00e+00	656.00
IUUC-Meu-056042	Macropus eugenii	77.24	7.00e-114	402.00
IUUC-Mor-057187	Magnaporthe oryzae	32.70	3.00e-39	155.00
IUUC-Mtr-058072	Medicago truncatula	48.51	1.00e-87	316.00
IUUC-Mla-059108	Melampsora laricipopulina	32.12	4.00e-52	198.00
IUUC-Mga-059370	Meleagris gallopavo	64.09	1.00e-101	362.00
IUUC-Mvi-060495	Microbotryum violaceum	36.91	7.00e-58	218.00
IUUC-Mmr-060902	Microcebus murinus	97.64	0.00e+00	643.00
IUUC-Mdo-062510	Monodelphis domestica	92.92	8.00e-173	599.00
IUUC-Mmu-063575	Mus musculus	94.99	0.00e+00	630.00
IUUC-Mac-065322	Musa acuminata	50.74	2.00e-92	332.00
IUUC-Mpu-065925	Mustela putorius furo	96.76	0.00e+00	638.00
IUUC-Mlu-067755	Myotis lucifugus	96.76	0.00e+00	637.00
IUUC-Nfi-068327	Neosartorya fischeri	31.22	2.00e-48	186.00
IUUC-Ncr-068845	Neurospora crassa	33.54	4.00e-33	135.00
IUUC-Nle-069406	Nomascus leucogenys	97.35	0.00e+00	637.00
IUUC-Opr-070416	Ochotona princeps	97.55	3.00e-79	288.00
IUUC-Ont-071936	Oreochromis niloticus	75.67	3.00e-144	504.00
IUUC-Oan-073452	Ornithorhynchus anatinus	92.73	5.00e-77	279.00
IUUC-Ocu-074791	Oryctolagus cuniculus	95.87	0.00e+00	634.00
IUUC-Oba-075636	Oryza barthii	49.55	1.00e-89	323.00
IUUC-Obr-076742	Oryza brachyantha	48.60	7.00e-78	283.00
IUUC-Ogl-077766	Oryza glaberrima	49.55	1.00e-89	323.00
IUUC-Ogu-079039	Oryza glumaepatula	49.55	4.00e-90	324.00
IUUC-Oin-079315	Oryza indica	49.32	9.00e-79	286.00
IUUC-Olo-080669	Oryza longistaminata	44.01	9.00e-82	296.00
IUUC-Ome-081490	Oryza meridionalis	49.55	8.00e-90	323.00
IUUC-Oni-082572	Oryza nivara	49.55	1.00e-89	323.00
IUUC-Opu-083732	Oryza punctata	48.85	5.00e-90	324.00
IUUC-Oru-084763	Oryza rufipogon	49.55	1.00e-89	323.00
IUUC-Osa-085372	Oryza sativa	49.55	1.00e-89	323.00
IUUC-Ola-087379	Oryzias latipes	73.53	2.00e-140	491.00
IUUC-Olu-087801	Ostreococcus lucimarinus	35.75	3.00e-44	172.00
IUUC-Oga-089076	Otolemur garnettii	97.05	0.00e+00	639.00
IUUC-Oar-090022	Ovis aries	93.22	1.00e-177	615.00
IUUC-Ptr-090809	Pan troglodytes	100.00	0.00e+00	659.00
IUUC-Psi-093046	Pelodiscus sinensis	88.13	7.00e-170	589.00
IUUC-Pma-094181	Petromyzon marinus	63.80	2.00e-132	464.00
IUUC-Pno-094882	Phaeosphaeria nodorum	34.79	6.00e-56	211.00
IUUC-Ppa-095172	Physcomitrella patens	47.38	5.00e-87	314.00
IUUC-Pfo-096396	Poecilia formosa	72.11	2.00e-140	491.00
IUUC-Pab-098427	Pongo abelii	99.41	0.00e+00	650.00
IUUC-Pop-100016	Populus trichocarpa	51.79	1.00e-91	329.00
IUUC-Pca-101048	Procavia capensis	95.58	0.00e+00	631.00
IUUC-Ppe-102050	Prunus persica	47.52	7.00e-88	317.00
IUUC-Pva-103117	Pteropus vampyrus	96.17	0.00e+00	634.00
IUUC-Pgr-103307	Puccinia graminis	34.29	4.00e-59	221.00
IUUC-Ptt-103938	Puccinia triticina	39.10	1.00e-49	189.00
IUUC-Pte-104315	Pyrenophora teres	34.57	4.00e-57	215.00
IUUC-Pyt-104825	Pyrenophora triticirepentis	34.32	5.00e-56	211.00
IUUC-Rno-105523	Rattus norvegicus	94.40	0.00e+00	627.00
IUUC-Sce-106297	Saccharomyces cerevisiae	42.27	5.00e-66	244.00
IUUC-Sha-106981	Sarcophilus harrisii	92.15	1.00e-144	505.00
IUUC-Sja-107715	Schizosaccharomyces japonicus	38.75	2.00e-56	213.00
IUUC-Spo-108214	Schizosaccharomyces pombe	40.20	1.00e-58	221.00
IUUC-Smo-109034	Selaginella moellendorffii	45.33	1.00e-82	299.00
IUUC-Sit-110663	Setaria italica	50.44	1.00e-90	326.00
IUUC-Sly-110898	Solanum lycopersicum	47.38	7.00e-84	303.00
IUUC-Stu-112647	Solanum tuberosum	50.75	2.00e-71	262.00
IUUC-Sbi-114288	Sorghum bicolor	48.09	3.00e-86	311.00
IUUC-Sre-115065	Sporisorium reilianum	43.69	5.00e-76	278.00
IUUC-Ssc-115960	Sus scrofa	89.61	3.00e-180	624.00
IUUC-Tru-118382	Takifugu rubripes	71.22	3.00e-149	521.00
IUUC-Tsy-119585	Tarsius syrichta	89.09	1.00e-165	575.00
IUUC-Tni-120133	Tetraodon nigroviridis	74.85	2.00e-145	508.00
IUUC-Tca-121167	Theobroma cacao	49.26	1.00e-82	300.00
IUUC-Tre-122119	Trichoderma reesei	29.22	6.00e-41	161.00
IUUC-Tvi-122407	Trichoderma virens	32.00	3.00e-40	159.00
IUUC-Tae-125748	Triticum aestivum	48.09	1.00e-82	300.00
IUUC-Tur-126682	Triticum urartu	48.52	7.00e-68	250.00
IUUC-Tme-127095	Tuber melanosporum	35.95	4.00e-61	228.00
IUUC-Tbe-128004	Tupaia belangeri	97.05	0.00e+00	641.00
IUUC-Ttr-129284	Tursiops truncatus	91.52	6.00e-172	596.00
IUUC-Uma-129527	Ustilago maydis	42.78	1.00e-74	273.00
IUUC-Vda-129854	Verticillium dahliae	31.52	5.00e-38	152.00
IUUC-Vpa-130681	Vicugna pacos	97.41	2.00e-50	192.00
IUUC-Vvi-131004	Vitis vinifera	53.45	9.00e-89	320.00
IUUC-Xtr-131928	Xenopus tropicalis	81.31	7.00e-157	546.00
IUUC-Xma-134290	Xiphophorus maculatus	70.92	6.00e-137	479.00
IUUC-Yli-134364	Yarrowia lipolytica	43.73	1.00e-67	249.00
IUUC-Zma-135658	Zea mays	49.55	3.00e-87	315.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence