iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133116

Ensembl Protein ID

ENSXMAP00000002153.1

UniProt Accession

M3ZIW1; M3ZIW1_XIPMA

Genbank Protein ID

ENSXMAP00000002153

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01008245

Gene Name

USP50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000002152.1	ENSXMAT00000002158.1	ENSXMAP00000002153.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-82	277.5	3	315

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+gN+CY+N+v+QcL ++ ++ e+ll+   +++++e   + +  +++ + +l+e++w++++++ sp +++++l ++ ++f++y q
   Q: 3    VGLDNIGNSCYFNAVMQCLCSTMPFVEDLLS---QETRREL-AKCECGIAQVFIELLEQMWQGSSTSCSPVQVMSTLPSVFPQFDSYTQ 87
           6******************************...5555443.578999***************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           qDaqE+l +lld+l+e+lkk      +++    +++++ +++++  k +++++sdlF+gql+  +  l+c+++    ++f+ lslp+p+
   Q: 88   QDAQELLLHLLDALHEDLKK------MHL----SRKQPGKNQSRSSKTESTIVSDLFEGQLSYLTSFLHCGHEARNSQTFTILSLPIPN 166
           ******************43......222....3455777889999999***************************************8 PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            ++  k s+qdcL+ f++e  l+g+++ yc+ c  ++ea+ ++ l+k Pe+LilhLkRf   +++ ++ k++ +v+f  eLd++pf++s
   Q: 167  GNK--KWSIQDCLSLFFEETVLTGAEQTYCSDCGLRREATVQTYLNKPPEILILHLKRF--GCKGRRQVKLSANVSFSMELDITPFLSS 251
           774..46****************************************************..88999*********************** PP
   S: 268  peekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           + ++     +Y L+avv+H G+l+ GHY+a+++n+  + W  fdDs V+ev+ + v++    +aYvlfY 
   Q: 252  SVRS---WSSYHLYAVVIHRGNLDMGHYTALCYNSVLEtWHWFDDSLVKEVHGSVVQS---PDAYVLFYS 315
           6655...79*************************88889*******************...********6 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

GVVGLDNIGN SCYFNAVMQC LCSTMPFVED LLSQETRREL AKCECGIAQV FIELLEQMWQ 60
GSSTSCSPVQ VMSTLPSVFP QFDSYTQQDA QELLLHLLDA LHEDLKKMHL SRKQPGKNQS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGTTGTTG GGTTAGACAA CATCGGCAAT TCGTGCTACT TCAATGCTGT GATGCAGTGT 60
CTCTGTTCAA CCATGCCCTT TGTAGAAGAC CTCCTCAGTC AGGAAACACG CAGAGAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gac-042261	Gasterosteus aculeatus	59.16	1.00e-103	369.00
IUUC-Loc-051880	Lepisosteus oculatus	47.85	1.00e-74	274.00
IUUC-Ont-072200	Oreochromis niloticus	64.11	4.00e-108	384.00
IUUC-Ola-086857	Oryzias latipes	54.55	8.00e-97	347.00
IUUC-Pfo-096718	Poecilia formosa	91.08	3.00e-160	558.00
IUUC-Tru-118574	Takifugu rubripes	59.01	8.00e-100	357.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence