iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088634

Ensembl Protein ID

ENSOGAP00000007332.2

UniProt Accession

H0WXX5; H0WXX5_OTOGA

Genbank Protein ID

ENSOGAP00000007332

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03028218

Gene Name

ELP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000008189.2	ENSOGAT00000008196.2	ENSOGAP00000007332.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-44	147.8	273	306
UBD/Beta-Prp	2.20e-47	161.7	640	892

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDl 30
           gH+d+++++++     d +l+s+s D+ i++W l
   Q: 273  GHEDWIRGVEWaaigGDLFLASCSQDCLIRIWKL 306
           8*************76699*************96 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgs.....rdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvw....dls.......... 82
           i cv++ ++k+lla+++     + + i++w++t++k ++ l  h+ +vt++ fsp++k+l+ +s+Drt  +w                 
   Q: 640  IFCVACNNSKTLLASACkaakkEHAAIILWNTTSWKQVQNLVFHSLTVTQMAFSPNDKFLLAVSRDRTWSLWkrqdT-Ispefdpifsl 727
           66899999999999999332223567**********************************************77741.35756666776 PP
   S: 83   .tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwd..letgqclee..........tlsghdgvvncvvvhpdg.nllvsGsl 157
            +++  +t   h++ ++s+++sp+++++ +Gs+d+ + vw     ++ c+e+          +    ++v  c  +++++  +++ G  
   Q: 728  fAFTNKITS-VHSRIIWSCDWSPDSKYFFTGSRDKKVVVWGecDASDDCIEHnigpcssvldVGGAVTAVSVCPMFSSSQrYVVAVGLE 815
           633333333.48899*************************7445678888889***999877666666666777777777355556667 PP
   S: 158  DrtvrlWdl..........ktgkllrtl..tgghtdsvyslsfdsng.............kelvsgsldgtvklwdlq 210
            +++ l+               ++++t   ++ ht ++++l ++  +              +++s+++d tvk++ + 
   Q: 816  CGKICLYTWkktdqvpeinDWIQCVETSqsQS-HTLAIKKLCWKNCSgntdqseaegsewLHFASCGEDHTVKIYRVN 892
           79999999965555554444444444447444.888888888666557778888999*99***************985 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MVAPVLETSH VFCCPNRVRG VLSWSSGPGG LLAFGTSCSV VLYDPLKRVV VTNLNGHTAR 60
VNCVQWICKQ DGSPSTELVS GGSDNQVIHW EIENNQLLKA VHLQGHEGPV YAVHAVYQRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAACATGGT GGCACCCGTG CTCGAGACTT CTCACGTGTT TTGCTGCCCA AACCGGGTGC 60
GAGGTGTCCT GAGCTGGAGC TCCGGGCCAG GAGGACTTCT GGCCTTTGGC ACGTCCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0033588--C:Elongator holoenzyme complex
GO:0000123--C:histone acetyltransferase complex
GO:0008023--C:transcription elongation factor complex
GO:0046425--P:regulation of JAK-STAT cascade

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000056	Aegilops tauschii	34.32	6.00e-97	348.00
IUUC-Aml-002049	Ailuropoda melanoleuca	80.73	0.00e+00	1214.00
IUUC-Atr-002456	Amborella trichopoda	33.33	8.00e-109	388.00
IUUC-Apl-004053	Anas platyrhynchos	58.05	0.00e+00	897.00
IUUC-Aca-004535	Anolis carolinensis	56.45	0.00e+00	972.00
IUUC-Aly-005746	Arabidopsis lyrata	30.12	5.00e-97	348.00
IUUC-Ath-006664	Arabidopsis thaliana	34.30	9.00e-94	338.00
IUUC-Ago-007971	Ashbya gossypii	31.78	1.00e-78	288.00
IUUC-Acl-008173	Aspergillus clavatus	29.75	4.00e-92	332.00
IUUC-Afl-008665	Aspergillus flavus	24.95	2.00e-28	120.00
IUUC-Afu-008976	Aspergillus fumigatus	33.08	8.00e-83	301.00
IUUC-Ani-009284	Aspergillus nidulans	31.43	1.00e-86	314.00
IUUC-Ang-009809	Aspergillus niger	32.30	2.00e-81	296.00
IUUC-Aor-009959	Aspergillus oryzae	28.76	5.00e-82	299.00
IUUC-Ate-010442	Aspergillus terreus	28.25	6.00e-83	302.00
IUUC-Ame-011409	Astyanax mexicanus	45.53	0.00e+00	729.00
IUUC-Bgr-012137	Blumeria graminis	29.32	2.00e-89	323.00
IUUC-Bta-012892	Bos taurus	71.76	0.00e+00	1264.00
IUUC-Bci-013944	Botrytis cinerea	29.02	2.00e-76	280.00
IUUC-Bdi-014512	Brachypodium distachyon	35.56	5.00e-95	342.00
IUUC-Bol-015741	Brassica oleracea	30.65	2.00e-99	357.00
IUUC-Bra-017367	Brassica rapa	30.59	6.00e-98	352.00
IUUC-Cel-018712	Caenorhabditis elegans	31.94	4.00e-79	289.00
IUUC-Cja-018865	Callithrix jacchus	82.92	0.00e+00	1519.00
IUUC-Cfa-021006	Canis familiaris	86.24	0.00e+00	1177.00
IUUC-Cpo-021370	Cavia porcellus	64.64	0.00e+00	1096.00
IUUC-Csa-023845	Chlorocebus sabaeus	74.12	0.00e+00	1311.00
IUUC-Cho-024640	Choloepus hoffmanni	68.21	0.00e+00	739.00
IUUC-Cin-025772	Ciona intestinalis	37.30	9.00e-135	474.00
IUUC-Csv-025891	Ciona savignyi	42.53	2.00e-133	469.00
IUUC-Cgl-026443	Colletotrichum gloeosporioides	28.08	1.00e-83	304.00
IUUC-Cne-027081	Cryptococcus neoformans	31.92	1.00e-80	294.00
IUUC-Cme-027225	Cyanidioschyzon merolae	27.05	8.00e-40	159.00
IUUC-Dre-028250	Danio rerio	54.43	0.00e+00	747.00
IUUC-Dno-028847	Dasypus novemcinctus	72.22	0.00e+00	1266.00
IUUC-Dor-030351	Dipodomys ordii	84.93	0.00e+00	1089.00
IUUC-Dse-031317	Dothistroma septosporum	29.72	6.00e-80	292.00
IUUC-Dme-032019	Drosophila melanogaster	36.80	4.00e-161	561.00
IUUC-Ete-033194	Echinops telfairi	88.05	1.00e-171	596.00
IUUC-Eca-033779	Equus caballus	70.44	0.00e+00	1231.00
IUUC-Eeu-034790	Erinaceus europaeus	70.89	0.00e+00	867.00
IUUC-Fca-036090	Felis catus	70.12	0.00e+00	1119.00
IUUC-Fal-037663	Ficedula albicollis	58.49	0.00e+00	974.00
IUUC-Fox-037828	Fusarium oxysporum	31.49	8.00e-82	298.00
IUUC-Fso-038462	Fusarium solani	33.28	1.00e-81	298.00
IUUC-Gmo-039450	Gadus morhua	46.70	0.00e+00	775.00
IUUC-Ggr-040023	Gaeumannomyces graminis	30.30	1.00e-65	244.00
IUUC-Gga-040480	Gallus gallus	54.80	0.00e+00	932.00
IUUC-Gac-041544	Gasterosteus aculeatus	48.16	0.00e+00	814.00
IUUC-Gma-044048	Glycine max	36.78	2.00e-104	373.00
IUUC-Ggo-045381	Gorilla gorilla	72.51	0.00e+00	1290.00
IUUC-Hsa-046096	Homo sapiens	85.04	0.00e+00	1554.00
IUUC-Hvu-047494	Hordeum vulgare	34.62	6.00e-98	352.00
IUUC-Itr-048823	Ictidomys tridecemlineatus	76.26	0.00e+00	1270.00
IUUC-Kpa-049241	Komagataella pastoris	31.94	1.00e-81	298.00
IUUC-Lch-050512	Latimeria chalumnae	57.00	0.00e+00	1008.00
IUUC-Lpe-051448	Leersia perrieri	31.70	2.00e-104	373.00
IUUC-Loc-051882	Lepisosteus oculatus	52.67	0.00e+00	920.00
IUUC-Lma-053023	Leptosphaeria maculans	30.95	1.00e-87	318.00
IUUC-Laf-054519	Loxodonta africana	71.78	0.00e+00	1280.00
IUUC-Mcc-055580	Macaca mulatta	84.49	0.00e+00	1530.00
IUUC-Meu-056606	Macropus eugenii	68.82	7.00e-110	391.00
IUUC-Mor-057109	Magnaporthe oryzae	28.31	2.00e-77	284.00
IUUC-Mpo-057297	Magnaporthe poae	27.93	5.00e-72	265.00
IUUC-Mtr-058348	Medicago truncatula	36.48	7.00e-102	365.00
IUUC-Mla-059159	Melampsora laricipopulina	31.66	2.00e-71	264.00
IUUC-Mga-059778	Meleagris gallopavo	57.19	0.00e+00	645.00
IUUC-Mvi-060447	Microbotryum violaceum	28.88	5.00e-84	305.00
IUUC-Mmr-061139	Microcebus murinus	85.54	0.00e+00	1553.00
IUUC-Mdo-061866	Monodelphis domestica	58.30	0.00e+00	1040.00
IUUC-Mmu-063390	Mus musculus	62.68	0.00e+00	1073.00
IUUC-Mac-064693	Musa acuminata	31.79	2.00e-112	399.00
IUUC-Mpu-066547	Mustela putorius furo	85.63	0.00e+00	1164.00
IUUC-Mlu-067156	Myotis lucifugus	70.09	0.00e+00	1235.00
IUUC-Nfi-068616	Neosartorya fischeri	31.98	1.00e-83	304.00
IUUC-Ncr-068915	Neurospora crassa	26.30	3.00e-67	250.00
IUUC-Nle-069958	Nomascus leucogenys	72.03	0.00e+00	1258.00
IUUC-Opr-071093	Ochotona princeps	51.05	4.00e-159	555.00
IUUC-Ont-072178	Oreochromis niloticus	49.83	0.00e+00	830.00
IUUC-Oan-073667	Ornithorhynchus anatinus	55.92	0.00e+00	932.00
IUUC-Ocu-074662	Oryctolagus cuniculus	70.11	0.00e+00	1217.00
IUUC-Oba-075577	Oryza barthii	32.42	2.00e-109	390.00
IUUC-Obr-076566	Oryza brachyantha	32.07	5.00e-110	392.00
IUUC-Ogl-077054	Oryza glaberrima	32.38	4.00e-109	389.00
IUUC-Ogu-078846	Oryza glumaepatula	32.53	3.00e-109	389.00
IUUC-Oin-079084	Oryza indica	32.42	2.00e-109	390.00
IUUC-Olo-080933	Oryza longistaminata	29.75	9.00e-85	308.00
IUUC-Ome-081500	Oryza meridionalis	30.56	1.00e-93	337.00
IUUC-Oni-082352	Oryza nivara	32.12	4.00e-108	385.00
IUUC-Opu-084116	Oryza punctata	35.82	2.00e-100	360.00
IUUC-Oru-085249	Oryza rufipogon	32.42	2.00e-109	390.00
IUUC-Osa-086270	Oryza sativa	32.42	2.00e-109	390.00
IUUC-Ola-086625	Oryzias latipes	43.52	0.00e+00	689.00
IUUC-Olu-087638	Ostreococcus lucimarinus	29.90	3.00e-69	256.00
IUUC-Oar-089475	Ovis aries	85.52	0.00e+00	1162.00
IUUC-Ptr-091131	Pan troglodytes	74.45	0.00e+00	1318.00
IUUC-Pan-092869	Papio anubis	73.16	0.00e+00	1290.00
IUUC-Psi-093146	Pelodiscus sinensis	66.02	0.00e+00	927.00
IUUC-Pma-094479	Petromyzon marinus	46.15	0.00e+00	757.00
IUUC-Pno-095061	Phaeosphaeria nodorum	30.74	1.00e-57	218.00
IUUC-Ppa-095618	Physcomitrella patens	34.85	1.00e-105	378.00
IUUC-Pfo-096816	Poecilia formosa	46.38	0.00e+00	791.00
IUUC-Pab-097548	Pongo abelii	74.12	0.00e+00	1310.00
IUUC-Pop-099643	Populus trichocarpa	32.51	2.00e-115	410.00
IUUC-Pca-100983	Procavia capensis	58.59	1.00e-156	546.00
IUUC-Ppe-101301	Prunus persica	31.62	2.00e-108	387.00
IUUC-Pva-102460	Pteropus vampyrus	70.44	0.00e+00	1219.00
IUUC-Pgr-103507	Puccinia graminis	29.71	1.00e-61	231.00
IUUC-Ptt-103892	Puccinia triticina	29.41	2.00e-49	190.00
IUUC-Pte-104283	Pyrenophora teres	29.43	5.00e-87	315.00
IUUC-Pyt-104465	Pyrenophora triticirepentis	28.91	5.00e-83	302.00
IUUC-Rno-105842	Rattus norvegicus	63.44	0.00e+00	1088.00
IUUC-Sce-106459	Saccharomyces cerevisiae	27.98	4.00e-84	306.00
IUUC-Sha-106586	Sarcophilus harrisii	54.52	0.00e+00	937.00
IUUC-Sja-107868	Schizosaccharomyces japonicus	33.22	4.00e-73	269.00
IUUC-Spo-108302	Schizosaccharomyces pombe	29.61	2.00e-78	287.00
IUUC-Smo-108861	Selaginella moellendorffii	36.87	3.00e-111	395.00
IUUC-Sit-109915	Setaria italica	35.01	6.00e-100	358.00
IUUC-Sly-111714	Solanum lycopersicum	35.61	7.00e-106	378.00
IUUC-Stu-112631	Solanum tuberosum	35.38	2.00e-103	370.00
IUUC-Sar-113200	Sorex araneus	62.72	0.00e+00	1065.00
IUUC-Sbi-114582	Sorghum bicolor	36.36	6.00e-103	368.00
IUUC-Sre-115001	Sporisorium reilianum	31.79	8.00e-40	159.00
IUUC-Ssc-115519	Sus scrofa	70.33	0.00e+00	1220.00
IUUC-Tgu-116987	Taeniopygia guttata	52.93	0.00e+00	879.00
IUUC-Tru-118476	Takifugu rubripes	48.08	0.00e+00	775.00
IUUC-Tsy-119230	Tarsius syrichta	68.43	8.00e-172	597.00
IUUC-Tni-120448	Tetraodon nigroviridis	35.56	1.00e-103	370.00
IUUC-Tca-121650	Theobroma cacao	35.88	1.00e-102	367.00
IUUC-Tre-122086	Trichoderma reesei	32.37	8.00e-74	271.00
IUUC-Tvi-122397	Trichoderma virens	32.42	4.00e-70	259.00
IUUC-Tae-125778	Triticum aestivum	34.87	7.00e-98	351.00
IUUC-Tur-126578	Triticum urartu	34.62	3.00e-97	350.00
IUUC-Tme-126927	Tuber melanosporum	30.26	1.00e-78	288.00
IUUC-Tbe-127922	Tupaia belangeri	74.77	4.00e-85	309.00
IUUC-Ttr-128918	Tursiops truncatus	70.78	0.00e+00	1236.00
IUUC-Uma-129474	Ustilago maydis	28.22	3.00e-38	154.00
IUUC-Vda-129944	Verticillium dahliae	29.58	2.00e-70	260.00
IUUC-Vpa-130693	Vicugna pacos	66.89	0.00e+00	1149.00
IUUC-Vvi-130949	Vitis vinifera	35.24	2.00e-101	363.00
IUUC-Xtr-132639	Xenopus tropicalis	53.83	0.00e+00	961.00
IUUC-Xma-134223	Xiphophorus maculatus	55.34	2.00e-164	572.00
IUUC-Yli-134601	Yarrowia lipolytica	34.89	1.00e-92	334.00
IUUC-Zma-135952	Zea mays	33.52	7.00e-113	401.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence