iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133900

Ensembl Protein ID

ENSXMAP00000004509.1

UniProt Accession

M3ZQL6; M3ZQL6_XIPMA

Genbank Protein ID

ENSXMAP00000004509

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01038775

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000004468.1	ENSXMAT00000004514.1	ENSXMAP00000004509.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-54	178.9	42	80
UBD/Beta-Prp	2.30e-127	424.3	657	872

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           H+ +v claf sd  +l+s + D  +t+ +WD+r+g+++
   Q: 42   HSHGVACLAFdSDgQRLASVGLDakNTVCIWDWRRGRVV 80
           999********999*******9999**********9976 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ ++ ++++p k+++a++  +rd  i +wd++t k+l+ +   h++++ a++f  dgk lv+++ D  + i +wd ++g+ + + 
   Q: 657  GHDDDILS-LAVHPLKDYVASAqvGRDPAIHIWDIQTLKCLSLVkGHHSKGICALDFTADGKSLVSVGIDefHSIVIWDWKKGERLAKA 744
           45555555.99********9974479**************99995557899*******************9999*************** PP
   S: 91   kghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++  ++++p   dklv+ +  + i+ w+++ g    +     + g++++ +++++  ++++++sG++++ v +W  k  +l++t
   Q: 745  RGHKDKIFVVKSNPfRVDKLVTVG-IKHIKFWQHSGGGLTFKrgifGNLGKQETMMSACYGRSEDMVFSGATNGDVYIW--KETTLMKT 830
           **************5559999988.9******9999888777899888899999********99***************..88****** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            +  h+++v  +   +ng  +v+g++dg v+lwd   ++c++t+ 
   Q: 831  IKA-HDGPVFAMCSLDNG--FVTGGKDGIVELWDDMFERCLKTYA 872
           *98.*********99976..*********************9996 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

VRSLAIHPDK IQVATGQVGK DPYICIWDTY AMQTVSILRD VHSHGVACLA FDSDGQRLAS 60
VGLDAKNTVC IWDWRRGRVV AMATGHSDRI FDVCWDPFQT SRLVSCGVKH IKFWTLCGNA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCGCAGCC TGGCCATCCA CCCGGATAAG ATCCAGGTGG CGACGGGTCA GGTGGGGAAA 60
GACCCGTACA TCTGCATCTG GGACACCTAC GCCATGCAGA CCGTCTCTAT CCTGAGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	79.60	0.00e+00	3110.00
IUUC-Apl-003604	Anas platyrhynchos	79.56	0.00e+00	3093.00
IUUC-Aca-004572	Anolis carolinensis	76.91	0.00e+00	3026.00
IUUC-Ame-010713	Astyanax mexicanus	85.48	0.00e+00	3298.00
IUUC-Bta-012812	Bos taurus	79.60	0.00e+00	3110.00
IUUC-Cja-019191	Callithrix jacchus	79.34	0.00e+00	3105.00
IUUC-Cfa-020041	Canis familiaris	79.56	0.00e+00	2887.00
IUUC-Csa-023689	Chlorocebus sabaeus	79.35	0.00e+00	3103.00
IUUC-Cho-025038	Choloepus hoffmanni	77.72	0.00e+00	1189.00
IUUC-Dno-029982	Dasypus novemcinctus	78.30	0.00e+00	3061.00
IUUC-Eca-034161	Equus caballus	78.29	0.00e+00	3059.00
IUUC-Fca-036307	Felis catus	79.86	0.00e+00	3122.00
IUUC-Fal-037332	Ficedula albicollis	78.02	0.00e+00	3064.00
IUUC-Gmo-039057	Gadus morhua	82.90	0.00e+00	3179.00
IUUC-Gac-042555	Gasterosteus aculeatus	92.19	0.00e+00	3554.00
IUUC-Ggo-045107	Gorilla gorilla	79.55	0.00e+00	3115.00
IUUC-Hsa-046482	Homo sapiens	79.65	0.00e+00	3113.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	78.46	0.00e+00	3106.00
IUUC-Loc-052642	Lepisosteus oculatus	84.03	0.00e+00	3259.00
IUUC-Laf-053649	Loxodonta africana	79.33	0.00e+00	3075.00
IUUC-Mcc-055361	Macaca mulatta	79.48	0.00e+00	2796.00
IUUC-Mga-059202	Meleagris gallopavo	79.24	0.00e+00	3084.00
IUUC-Mmr-060729	Microcebus murinus	79.85	0.00e+00	3120.00
IUUC-Mdo-062462	Monodelphis domestica	79.81	0.00e+00	3125.00
IUUC-Mmu-063865	Mus musculus	79.07	0.00e+00	3123.00
IUUC-Mpu-066724	Mustela putorius furo	79.76	0.00e+00	3119.00
IUUC-Mlu-067816	Myotis lucifugus	79.39	0.00e+00	3111.00
IUUC-Opr-070213	Ochotona princeps	77.02	0.00e+00	1671.00
IUUC-Ont-071928	Oreochromis niloticus	77.86	0.00e+00	3053.00
IUUC-Oan-073563	Ornithorhynchus anatinus	79.61	0.00e+00	3109.00
IUUC-Ocu-074531	Oryctolagus cuniculus	79.76	0.00e+00	3116.00
IUUC-Ola-086943	Oryzias latipes	76.75	0.00e+00	3049.00
IUUC-Oga-088665	Otolemur garnettii	79.15	0.00e+00	3097.00
IUUC-Oar-090429	Ovis aries	79.71	0.00e+00	3113.00
IUUC-Psi-093281	Pelodiscus sinensis	78.40	0.00e+00	3046.00
IUUC-Pfo-096150	Poecilia formosa	98.72	0.00e+00	3576.00
IUUC-Rno-105002	Rattus norvegicus	79.18	0.00e+00	3118.00
IUUC-Sha-107105	Sarcophilus harrisii	77.65	0.00e+00	3017.00
IUUC-Ssc-116282	Sus scrofa	79.86	0.00e+00	3122.00
IUUC-Tgu-116807	Taeniopygia guttata	79.23	0.00e+00	3075.00
IUUC-Tru-118040	Takifugu rubripes	89.97	0.00e+00	3462.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence