iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073180

UUCD1 version

UUC-OrA-00654

Ensembl Protein ID

ENSOANP00000021492.1

UniProt Accession

F7F9X1; F7F9X1_ORNAN

Protein Name

Uncharacterized protein

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000013625.3	ENSOANT00000021495.1	ENSOANP00000021492.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.60e-17	62.7	66	131
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.40e-10	38.4	165	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k +  +ei+d + ++ ++l+kF+Y+++l++
   Q: 66   CDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAK-QTLIEIRDFDGDAIEDLVKFVYSSRLTL 131
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+++++ hF+
   Q: 165  PSNCLAVRAFAESHNRIDLMDMADRYACEHFT 196
           89*****************************7 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MASDSVIPEQ AKNHLTQKGK RQQQQQPPEK SSQSDGEEDA FIFEANEAWK DFHGSLLRFY 60
EDGELCDVTL KVGSKLISCH KLVLACVIPY FRAMFLSEMA EAKQTLIEIR DFDGDAIEDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG ATTCTGTGAT CCCAGAACAA GCTAAGAATC ATTTGACGCA AAAGGGCAAA 60
AGGCAACAGC AGCAGCAGCC GCCAGAAAAG TCATCCCAGA GTGATGGGGA AGAAGACGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

oaa:100085523

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	93.39	0.00e+00	1174.00
IUUC-Atr-002726	Amborella trichopoda	36.63	6.00e-43	168.00
IUUC-Apl-003978	Anas platyrhynchos	91.44	0.00e+00	1171.00
IUUC-Aca-004958	Anolis carolinensis	87.44	0.00e+00	1097.00
IUUC-Ame-011139	Astyanax mexicanus	82.71	0.00e+00	1080.00
IUUC-Bgr-012290	Blumeria graminis	27.44	6.00e-09	55.10
IUUC-Bta-013142	Bos taurus	91.61	0.00e+00	1154.00
IUUC-Bdi-014143	Brachypodium distachyon	37.87	7.00e-43	168.00
IUUC-Cel-018551	Caenorhabditis elegans	41.41	1.00e-129	456.00
IUUC-Cja-019650	Callithrix jacchus	91.94	0.00e+00	1184.00
IUUC-Cfa-021046	Canis familiaris	93.06	0.00e+00	1167.00
IUUC-Cpo-022445	Cavia porcellus	89.84	0.00e+00	1112.00
IUUC-Csa-023642	Chlorocebus sabaeus	92.58	0.00e+00	1192.00
IUUC-Cho-025012	Choloepus hoffmanni	76.43	0.00e+00	862.00
IUUC-Dre-027723	Danio rerio	83.76	0.00e+00	1063.00
IUUC-Dno-028964	Dasypus novemcinctus	91.99	0.00e+00	973.00
IUUC-Dor-030899	Dipodomys ordii	79.47	7.00e-129	453.00
IUUC-Ete-032815	Echinops telfairi	88.87	0.00e+00	1141.00
IUUC-Eca-034162	Equus caballus	91.76	0.00e+00	1154.00
IUUC-Eeu-034660	Erinaceus europaeus	90.31	0.00e+00	1136.00
IUUC-Fca-035659	Felis catus	93.06	0.00e+00	1170.00
IUUC-Fal-037619	Ficedula albicollis	92.25	0.00e+00	1183.00
IUUC-Fox-037999	Fusarium oxysporum	29.87	8.00e-08	50.10
IUUC-Gmo-038546	Gadus morhua	84.88	0.00e+00	1051.00
IUUC-Gga-040770	Gallus gallus	91.76	0.00e+00	1153.00
IUUC-Gac-042557	Gasterosteus aculeatus	80.00	0.00e+00	1047.00
IUUC-Ggo-044741	Gorilla gorilla	92.26	0.00e+00	1191.00
IUUC-Hsa-046025	Homo sapiens	92.26	0.00e+00	1191.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	94.90	0.00e+00	1073.00
IUUC-Loc-052834	Lepisosteus oculatus	87.74	0.00e+00	1020.00
IUUC-Laf-054513	Loxodonta africana	90.31	0.00e+00	1160.00
IUUC-Mcc-054707	Macaca mulatta	92.42	0.00e+00	1188.00
IUUC-Meu-056779	Macropus eugenii	92.62	0.00e+00	1181.00
IUUC-Mtr-058180	Medicago truncatula	33.33	1.00e-36	147.00
IUUC-Mga-059676	Meleagris gallopavo	91.44	0.00e+00	1150.00
IUUC-Mmr-061359	Microcebus murinus	91.29	0.00e+00	1147.00
IUUC-Mdo-062527	Monodelphis domestica	91.67	0.00e+00	1171.00
IUUC-Mmu-063112	Mus musculus	87.80	0.00e+00	1145.00
IUUC-Mac-064682	Musa acuminata	35.47	1.00e-40	160.00
IUUC-Mpu-065800	Mustela putorius furo	92.90	0.00e+00	1167.00
IUUC-Mlu-067536	Myotis lucifugus	89.90	0.00e+00	1115.00
IUUC-Nle-069397	Nomascus leucogenys	92.26	0.00e+00	1189.00
IUUC-Opr-070599	Ochotona princeps	91.60	0.00e+00	968.00
IUUC-Ont-072580	Oreochromis niloticus	81.77	0.00e+00	1066.00
IUUC-Ocu-074026	Oryctolagus cuniculus	91.61	0.00e+00	1147.00
IUUC-Obr-076181	Oryza brachyantha	31.32	9.00e-36	145.00
IUUC-Ola-086776	Oryzias latipes	82.12	0.00e+00	1010.00
IUUC-Oga-088651	Otolemur garnettii	92.60	0.00e+00	1161.00
IUUC-Oar-089567	Ovis aries	90.48	0.00e+00	1127.00
IUUC-Ptr-091564	Pan troglodytes	92.26	0.00e+00	1191.00
IUUC-Pan-092578	Papio anubis	92.58	0.00e+00	1192.00
IUUC-Psi-093635	Pelodiscus sinensis	91.44	0.00e+00	1113.00
IUUC-Pma-094660	Petromyzon marinus	62.33	0.00e+00	766.00
IUUC-Pfo-097507	Poecilia formosa	81.76	0.00e+00	996.00
IUUC-Pab-098025	Pongo abelii	92.26	0.00e+00	1191.00
IUUC-Pca-101046	Procavia capensis	83.84	1.00e-175	609.00
IUUC-Ppe-101154	Prunus persica	32.16	6.00e-38	151.00
IUUC-Pva-102359	Pteropus vampyrus	95.00	0.00e+00	883.00
IUUC-Rno-105750	Rattus norvegicus	88.10	0.00e+00	1135.00
IUUC-Sha-107513	Sarcophilus harrisii	93.56	0.00e+00	1195.00
IUUC-Sly-111482	Solanum lycopersicum	31.76	1.00e-40	160.00
IUUC-Stu-112032	Solanum tuberosum	32.94	1.00e-42	167.00
IUUC-Sar-113616	Sorex araneus	69.52	2.00e-115	409.00
IUUC-Ssc-116205	Sus scrofa	92.40	0.00e+00	978.00
IUUC-Tgu-117435	Taeniopygia guttata	92.41	0.00e+00	1182.00
IUUC-Tru-118709	Takifugu rubripes	80.84	0.00e+00	1058.00
IUUC-Tsy-119466	Tarsius syrichta	94.89	0.00e+00	1072.00
IUUC-Tni-119988	Tetraodon nigroviridis	80.71	0.00e+00	1055.00
IUUC-Tca-120913	Theobroma cacao	33.94	3.00e-35	143.00
IUUC-Tbe-127704	Tupaia belangeri	93.07	0.00e+00	1030.00
IUUC-Ttr-128892	Tursiops truncatus	93.30	0.00e+00	887.00
IUUC-Vpa-130545	Vicugna pacos	92.97	0.00e+00	983.00
IUUC-Xtr-132289	Xenopus tropicalis	84.36	0.00e+00	1026.00
IUUC-Xma-133419	Xiphophorus maculatus	84.98	0.00e+00	959.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence