iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089322

Ensembl Protein ID

ENSOARP00000006273.1

UniProt Accession

W5P769; W5P769_SHEEP

Genbank Protein ID

ENSOARP00000006273

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01047008

Gene Name

TRIM32

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000005852.1	ENSOART00000006368.1	ENSOARP00000006273.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-06	28.7	20	64

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg...plvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C+iC+e+f ++   p++l CgH+++ +Cl+k+     ss +  rCP C
   Q: 20   CPICMESFTEEqlrPKLLHCGHTICCQCLEKL---LASSINGVRCPFC 64
           ********76667799*************888...67799999***** PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAAAAASHLN LDALREVLEC PICMESFTEE QLRPKLLHCG HTICCQCLEK LLASSINGVR 60
CPFCSKITLI TSLAQLTDNL TVLKIIDKTG LSEAVGLLMC RSCGRRLPRQ FCRSCGVVVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGCAG CCGCAGCCTC TCACCTGAAC CTGGACGCGC TGCGGGAAGT GCTGGAATGC 60
CCCATCTGCA TGGAGTCCTT CACGGAGGAG CAGCTGCGGC CCAAACTCCT GCACTGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001258--NHL_repeat
IPR013017--NHL_repeat_subgr
IPR033569--TRIM32
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51125--NHL
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01436--NHL
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0005863--C:striated muscle myosin thick filament
GO:0003723--F:RNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007014--P:actin ubiquitination
GO:0061564--P:axon development
GO:0045444--P:fat cell differentiation
GO:0045087--P:innate immune response
GO:0046716--P:muscle cell cellular homeostasis
GO:0048147--P:negative regulation of fibroblast proliferation
GO:1902230--P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0045787--P:positive regulation of cell cycle
GO:0030307--P:positive regulation of cell growth
GO:0030335--P:positive regulation of cell migration
GO:1903886--P:positive regulation of chemokine (C-C motif) ligand 20 production
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1903883--P:positive regulation of interleukin-17-mediated signaling pathway
GO:0045666--P:positive regulation of neuron differentiation
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045732--P:positive regulation of protein catabolic process
GO:0045862--P:positive regulation of proteolysis
GO:0051155--P:positive regulation of striated muscle cell differentiation
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0034612--P:response to tumor necrosis factor
GO:0009411--P:response to UV
GO:0001894--P:tissue homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001554	Ailuropoda melanoleuca	91.50	0.00e+00	739.00
IUUC-Aca-004290	Anolis carolinensis	82.97	0.00e+00	679.00
IUUC-Ame-011474	Astyanax mexicanus	61.11	2.00e-145	509.00
IUUC-Bta-013335	Bos taurus	95.63	0.00e+00	779.00
IUUC-Bol-015127	Brassica oleracea	43.08	2.00e-08	52.80
IUUC-Cja-019836	Callithrix jacchus	91.02	0.00e+00	737.00
IUUC-Cfa-020126	Canis familiaris	91.99	0.00e+00	748.00
IUUC-Cpo-021619	Cavia porcellus	91.02	0.00e+00	740.00
IUUC-Cre-022845	Chlamydomonas reinhardtii	43.40	2.00e-05	40.40
IUUC-Csa-023381	Chlorocebus sabaeus	91.50	0.00e+00	740.00
IUUC-Cho-024696	Choloepus hoffmanni	88.11	0.00e+00	698.00
IUUC-Dre-028768	Danio rerio	65.06	1.00e-151	530.00
IUUC-Dno-029162	Dasypus novemcinctus	91.75	0.00e+00	744.00
IUUC-Dor-030490	Dipodomys ordii	91.28	0.00e+00	716.00
IUUC-Ete-032250	Echinops telfairi	84.22	0.00e+00	669.00
IUUC-Eca-033392	Equus caballus	91.75	0.00e+00	742.00
IUUC-Fca-035512	Felis catus	92.23	0.00e+00	745.00
IUUC-Fal-036745	Ficedula albicollis	85.29	0.00e+00	692.00
IUUC-Gmo-038737	Gadus morhua	74.25	2.00e-138	486.00
IUUC-Gga-040258	Gallus gallus	84.56	0.00e+00	688.00
IUUC-Gac-041657	Gasterosteus aculeatus	61.50	5.00e-141	494.00
IUUC-Ggo-045473	Gorilla gorilla	91.99	0.00e+00	736.00
IUUC-Hsa-046653	Homo sapiens	91.75	0.00e+00	734.00
IUUC-Hvu-047109	Hordeum vulgare	34.38	3.00e-05	42.00
IUUC-Itr-048947	Ictidomys tridecemlineatus	91.99	0.00e+00	745.00
IUUC-Lch-049791	Latimeria chalumnae	70.69	2.00e-159	555.00
IUUC-Loc-052573	Lepisosteus oculatus	67.16	8.00e-154	537.00
IUUC-Laf-054514	Loxodonta africana	91.02	0.00e+00	738.00
IUUC-Mcc-055244	Macaca mulatta	91.50	0.00e+00	740.00
IUUC-Meu-056655	Macropus eugenii	80.88	0.00e+00	656.00
IUUC-Mtr-058731	Medicago truncatula	34.67	5.00e-09	55.80
IUUC-Mga-059343	Meleagris gallopavo	78.97	1.00e-178	619.00
IUUC-Mmr-061774	Microcebus murinus	91.26	0.00e+00	739.00
IUUC-Mmu-063743	Mus musculus	90.07	0.00e+00	733.00
IUUC-Mpu-066801	Mustela putorius furo	92.48	0.00e+00	747.00
IUUC-Nle-069880	Nomascus leucogenys	91.26	0.00e+00	739.00
IUUC-Ont-071805	Oreochromis niloticus	61.43	2.00e-144	506.00
IUUC-Oan-073221	Ornithorhynchus anatinus	68.45	0.00e+00	843.00
IUUC-Ocu-074609	Oryctolagus cuniculus	91.02	0.00e+00	738.00
IUUC-Olo-080692	Oryza longistaminata	38.46	2.00e-06	46.20
IUUC-Osa-086244	Oryza sativa	37.88	7.00e-07	48.10
IUUC-Oga-088597	Otolemur garnettii	91.26	0.00e+00	739.00
IUUC-Ptr-091638	Pan troglodytes	91.99	0.00e+00	736.00
IUUC-Pan-092001	Papio anubis	91.50	0.00e+00	740.00
IUUC-Psi-093112	Pelodiscus sinensis	85.78	0.00e+00	701.00
IUUC-Ppa-095766	Physcomitrella patens	37.35	4.00e-11	61.60
IUUC-Pfo-097226	Poecilia formosa	58.78	6.00e-139	488.00
IUUC-Pab-098115	Pongo abelii	91.50	0.00e+00	740.00
IUUC-Rno-104950	Rattus norvegicus	90.80	0.00e+00	734.00
IUUC-Sha-106842	Sarcophilus harrisii	85.05	0.00e+00	675.00
IUUC-Smo-109517	Selaginella moellendorffii	38.81	5.00e-09	52.00
IUUC-Sly-111588	Solanum lycopersicum	39.71	4.00e-08	51.60
IUUC-Ssc-115577	Sus scrofa	91.02	0.00e+00	735.00
IUUC-Tgu-116636	Taeniopygia guttata	84.80	0.00e+00	689.00
IUUC-Tsy-119479	Tarsius syrichta	91.75	0.00e+00	743.00
IUUC-Tni-120872	Tetraodon nigroviridis	58.35	6.00e-135	474.00
IUUC-Ttr-129170	Tursiops truncatus	92.23	0.00e+00	752.00
IUUC-Xtr-132839	Xenopus tropicalis	76.05	5.00e-177	614.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence