iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117648

UUCD1 version

UUC-TaR-00492

Ensembl Protein ID

ENSTRUP00000024083.1

UniProt Accession

H2THD3; H2THD3_TAKRU

Protein Name

Uncharacterized protein

Gene Name

LOC101070833

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000009584.1	ENSTRUT00000024182.1	ENSTRUP00000024083.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.40e-32	108.9	345	383
UBD/Beta-Prp	1.30e-57	196.5	213	508

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH + v++  f +d ++++s+s Dgt+k+W++++  +++
   Q: 345  GHLSFVNDAYFtQDgRHIISASADGTVKIWNTKSWECIH 383
           79999999999*888****************98877766 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheae........vtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           s + c  fspd+++l+tgs dg i+vw++ tgk  + l+ + +e        v +++fs+d+++l+tg++ + ikvw +++g c++ ++
   Q: 213  SHVECARFSPDGRYLITGSVDGFIEVWNFVTGKISKDLKYQAQEsfmmmddaVLCMCFSQDAELLATGAQNGKIKVWTIQSGLCLRRFE 301
           67899*****************************666644444446666666************************************9 PP
   S: 92   .ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl...t 176
            +h++ v++lsfs++++ ++s+s  + ir+ +l++g+ l+  l+gh ++vn + + +dg+ ++s+s+D+tv++W+ k+ ++++t    +
   Q: 302  hAHNKGVTCLSFSKDNNQILSASFNQSIRIHELRSGKTLK-ELTGHLSFVNDAYFTQDGRHIISASADGTVKIWNTKSWECIHTHksvS 389
           99**************************************.********************************************7774 PP
   S: 177  gghtdsvysls.fdsngkelvsgsldgtvklwdlqtgecvrtlnght...dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlq 261
            + + +v+ ++ + +  +++v + + +tv + +++ g++v+t+   +   + + +  +sp++e+++++++D +++++++++g+l ktl+
   Q: 390  RASEVPVNNVIpLPQHPEHFVVCNHSNTVVVLNMR-GQTVKTFSSGRqegAEFVCSTVSPRGEWIYCVGEDLVLYCFNYKTGKLQKTLT 477
           446677777765555569****************7.44455555544334888899999****************************** PP
   S: 262  lhnssvisvavlsfgdnvlvlgsedskvniwk 293
            h++ vi +++ ++ +n +++ sed+ +++wk
   Q: 478  VHEKEVIGITH-HPHENLIATYSEDGLLRLWK 508
           **********9.*******************8 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MATEMEPTDV IRLIMQYLKE NNLYRTLTTL QEETTLSLNT VESLDSFIAD INCGHWDSVL 60
MAIESLKLPD STLIDLYEQV VMELIEMREV GAARSLLRQT DPMIMLKQTQ PQRYLHLENL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTACAG AGATGGAGCC CACCGAGTAA GTCCTCTCTT CTTACCTTAT CTTCTCTCTT 60
TGGAGGGGTA AGATGATAAA ATGATGACGA GACCACCTGT GGGATTAGAA ACTGCGCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR006595--CTLH_C
IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

KEGG

tru:101070833

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gac-042232	Gasterosteus aculeatus	82.32	0.00e+00	877.00
IUUC-Ont-071251	Oreochromis niloticus	85.00	0.00e+00	836.00
IUUC-Ola-087442	Oryzias latipes	78.40	0.00e+00	787.00
IUUC-Pfo-097219	Poecilia formosa	82.00	0.00e+00	853.00
IUUC-Tni-119725	Tetraodon nigroviridis	94.09	0.00e+00	977.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence