iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Stu-112571

Ensembl Protein ID

PGSC0003DMT400018049

UniProt Accession

M1A9Y7; M1A9Y7_SOLTU

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PGSC0003DMG400007012	PGSC0003DMT400018049	PGSC0003DMT400018049

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	38.04	7.00e-40	162.00	IUUC-Hsa-046357
E3 activity/RING/RING	36.76	3.00e-40	163.00	IUUC-Mmu-064129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Solanum tuberosum

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MELDSIECVS SSDGMIDDDE IPLHHPHIIH SQYSSSKTPN NNNNNINNSS SNNDGIAAIH 60
STTSVHELLE CPVCTNSMYP PIHQCHNGHT ICSTCKARAH NRCPTCRQEL GDIRCLALEK 120

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Nucleotide Sequence
(Fasta)

AATCAATAAA AGTGGAAAAA AGCACCATTC TTTCCTCCAA GCAGAAGCTT AAAGGTTTCT 60
GTCTCTCTTC TTTTGTCTCT TCAATATCTG AATCAAAAAC AATGATTTGA AAAAGAAAAA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

sot:102601918

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	77.95	2.00e-125	441.00
IUUC-Aml-001186	Ailuropoda melanoleuca	36.76	1.00e-41	162.00
IUUC-Apl-003813	Anas platyrhynchos	36.76	8.00e-42	162.00
IUUC-Aca-005014	Anolis carolinensis	36.76	8.00e-42	162.00
IUUC-Aly-006522	Arabidopsis lyrata	76.28	1.00e-149	521.00
IUUC-Ath-007092	Arabidopsis thaliana	79.88	2.00e-153	533.00
IUUC-Bta-012887	Bos taurus	38.04	1.00e-41	162.00
IUUC-Bdi-014729	Brachypodium distachyon	77.22	6.00e-152	528.00
IUUC-Bol-015983	Brassica oleracea	85.30	3.00e-148	516.00
IUUC-Bra-016910	Brassica rapa	86.28	1.00e-148	517.00
IUUC-Cel-018320	Caenorhabditis elegans	33.33	4.00e-37	147.00
IUUC-Cja-019796	Callithrix jacchus	36.76	1.00e-41	162.00
IUUC-Cfa-020642	Canis familiaris	38.04	6.00e-42	163.00
IUUC-Cpo-022348	Cavia porcellus	36.76	8.00e-42	162.00
IUUC-Csa-023974	Chlorocebus sabaeus	38.04	1.00e-41	162.00
IUUC-Cho-024933	Choloepus hoffmanni	35.63	5.00e-38	149.00
IUUC-Dre-028041	Danio rerio	36.76	4.00e-42	164.00
IUUC-Dno-029764	Dasypus novemcinctus	38.04	1.00e-41	162.00
IUUC-Dor-030489	Dipodomys ordii	32.97	2.00e-20	90.50
IUUC-Eca-033536	Equus caballus	36.76	8.00e-42	162.00
IUUC-Fca-035362	Felis catus	38.04	1.00e-41	162.00
IUUC-Fal-037487	Ficedula albicollis	38.04	9.00e-42	162.00
IUUC-Gga-040269	Gallus gallus	36.76	8.00e-42	162.00
IUUC-Gac-042282	Gasterosteus aculeatus	36.76	3.00e-42	164.00
IUUC-Ggo-045444	Gorilla gorilla	38.04	1.00e-41	162.00
IUUC-Hsa-046357	Homo sapiens	38.04	1.00e-41	162.00
IUUC-Hvu-047574	Hordeum vulgare	77.95	1.00e-125	441.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	36.76	8.00e-42	162.00
IUUC-Lch-049504	Latimeria chalumnae	36.76	7.00e-42	162.00
IUUC-Lpe-050879	Leersia perrieri	80.31	6.00e-125	439.00
IUUC-Laf-053668	Loxodonta africana	36.76	8.00e-42	162.00
IUUC-Mcc-054640	Macaca mulatta	38.04	1.00e-41	162.00
IUUC-Meu-055922	Macropus eugenii	35.22	1.00e-36	145.00
IUUC-Mtr-058699	Medicago truncatula	81.38	2.00e-155	540.00
IUUC-Mga-059503	Meleagris gallopavo	36.76	9.00e-42	162.00
IUUC-Mmr-060794	Microcebus murinus	36.76	8.00e-42	162.00
IUUC-Mdo-061971	Monodelphis domestica	36.03	2.00e-38	151.00
IUUC-Mmu-064129	Mus musculus	36.76	5.00e-42	163.00
IUUC-Mac-065670	Musa acuminata	79.88	2.00e-156	543.00
IUUC-Mpu-066331	Mustela putorius furo	36.40	7.00e-42	163.00
IUUC-Mlu-067207	Myotis lucifugus	36.76	7.00e-42	162.00
IUUC-Nle-069706	Nomascus leucogenys	36.76	1.00e-41	162.00
IUUC-Ont-071849	Oreochromis niloticus	36.76	2.00e-42	164.00
IUUC-Ocu-074876	Oryctolagus cuniculus	36.76	1.00e-41	162.00
IUUC-Oba-075289	Oryza barthii	90.16	2.00e-139	487.00
IUUC-Ome-081318	Oryza meridionalis	81.10	6.00e-125	438.00
IUUC-Opu-084065	Oryza punctata	80.71	1.00e-124	437.00
IUUC-Ola-086814	Oryzias latipes	36.76	3.00e-42	164.00
IUUC-Oga-088114	Otolemur garnettii	38.49	4.00e-44	170.00
IUUC-Oar-089323	Ovis aries	36.76	1.00e-41	162.00
IUUC-Ptr-090692	Pan troglodytes	36.76	8.00e-42	162.00
IUUC-Pan-092012	Papio anubis	38.04	1.00e-41	162.00
IUUC-Psi-093687	Pelodiscus sinensis	38.04	8.00e-42	162.00
IUUC-Pfo-097134	Poecilia formosa	36.76	3.00e-42	164.00
IUUC-Pab-097555	Pongo abelii	38.04	1.00e-41	162.00
IUUC-Pop-100033	Populus trichocarpa	81.08	4.00e-156	542.00
IUUC-Pca-100328	Procavia capensis	34.41	8.00e-35	139.00
IUUC-Ppe-101960	Prunus persica	80.78	2.00e-160	556.00
IUUC-Rno-104866	Rattus norvegicus	36.76	5.00e-42	163.00
IUUC-Sha-106547	Sarcophilus harrisii	36.76	1.00e-41	162.00
IUUC-Smo-109412	Selaginella moellendorffii	86.77	1.00e-138	484.00
IUUC-Sly-111259	Solanum lycopersicum	97.00	0.00e+00	633.00
IUUC-Ssc-116441	Sus scrofa	35.63	7.00e-38	149.00
IUUC-Tgu-116579	Taeniopygia guttata	36.76	8.00e-42	162.00
IUUC-Tca-121517	Theobroma cacao	80.83	3.00e-159	552.00
IUUC-Tae-123647	Triticum aestivum	77.95	2.00e-125	441.00
IUUC-Ttr-129166	Tursiops truncatus	36.82	2.00e-39	154.00
IUUC-Vpa-130799	Vicugna pacos	31.98	2.00e-18	84.30
IUUC-Xtr-132553	Xenopus tropicalis	36.76	6.00e-42	162.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence