iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011768

Ensembl Protein ID

ENSAMXP00000001317.1

UniProt Accession

W5K157; W5K157_ASTMX

Genbank Protein ID

ENSAMXP00000001317

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01088375

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000001292.1	ENSAMXT00000001317.1	ENSAMXP00000001317.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.60e-07	30.2	362	401

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e+ kd +++ pCgH+ ++ Cl  w     ++s   +CP+Cr
   Q: 362  CKICTERDKD-TRIQPCGHLLCRPCLTGW-----QKSDGHTCPYCR 401
           99****9999.******************.....5677778****8 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MAMAGSTRGL GQSFELDPFD PPSQPPTNAD RKLLEKALKK LSKLHTLCTD SRLGLKNSPP 60
YLPDLVSETV ILLTEVWDPY RGPAPAVPRG DEADFLKIHV RHLLDKTNRA ILLFKEGKDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTAAATCA AGGGCCACAT TATTACAAAG ACTGTGTTTA ATCATTGGGC GAAGGAAGAC 60
ATGGGCAGTC TTTAGGCTGC AGAATAACGG AAGTGATTGA TATCAAGAAC CTTTGATGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dre-028626	Danio rerio	67.50	0.00e+00	749.00
IUUC-Ont-071754	Oreochromis niloticus	57.67	0.00e+00	645.00
IUUC-Pfo-096070	Poecilia formosa	62.60	1.00e-168	586.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence