iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133526

Ensembl Protein ID

ENSXMAP00000008010.1

UniProt Accession

M4A0L6; M4A0L6_XIPMA

Genbank Protein ID

ENSXMAP00000008010

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01016076

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000007971.1	ENSXMAT00000008018.1	ENSXMAP00000008010.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.20e-113	377.9	705	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdg 85
           ++k +++v+fv+     E+g+d++Gv++efl++++k+++np l+lf+++++++  l+p+p+s++++ +hl+lFef+G++lgka+++g
   Q: 705  SIKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKKVFNPALNLFKTTSGNE-RLYPSPTSYIHE-NHLQLFEFVGKMLGKAVYEG 789
           578899****************************************9888655.569*******76.******************** PP
   S: 86   rlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
            ++d+p++++f++++lg+       s+++l+++d+e+yk+l++ik++ + d+ +lgl+l++  +e+++g+  ++eL+pgG+++pVtn
   Q: 790  IVVDVPFASFFLSQVLGHhhstfYSSIDELPSLDSEFYKNLTSIKRY-DGDVGDLGLTLSY--DEDVMGQLVCHELIPGGKTMPVTN 873
           ******************777777999********************.7899998777776..5999******************** PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevl 253
           eNk +Y++l++++r++++ikeq++af +Gf+++i++e+l +F++ e++ li+G+ +eid++dlkk+t y gg+++++++i+w+w++l
   Q: 874  ENKISYIHLMAHFRMHTQIKEQTAAFIRGFRSIINPEWLHMFSTPEVQRLISGDnAEIDLDDLKKHTVYYGGFHSSHRVIIWLWDIL 960
           ******************************************************9******************************** PP
   S: 254  .eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeYss 315
            ++f++eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Ys+
   Q: 961  sSDFNAEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSK 1047
           999************************************************************9999******************** PP
   S: 316  keilkekLlyAieetkgFels 336
           k+il++kL+yAi++++gFels
   Q: 1048 KSILRDKLRYAISMNTGFELS 1068
           ******************985 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MFSVPQSSKS EFLDKARQAR EERKGHKEKE KAATQIQALV RRFLCRCRLQ KQTRKEVDDY 60
FQLSEAGTTK RNALSIFKIA RKLLFIYRLE DKMRFEKLCR AILASMEVEN EPKIWYVSLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGATTATGG CTGCAGTCTA TGTAGAGATC TCTTCTCATT GTTTACATTT AGAAACGGTG 60
TGTCTCCTGC GTTACAACAA ACTGACATCG TTCCAACATC AAACTCCGCC TCACCACGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

xma:102218544

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.79	4.00e-107	383.00
IUUC-Aml-002107	Ailuropoda melanoleuca	81.50	0.00e+00	1794.00
IUUC-Atr-003017	Amborella trichopoda	40.07	1.00e-114	407.00
IUUC-Apl-003328	Anas platyrhynchos	85.45	0.00e+00	1790.00
IUUC-Aly-005794	Arabidopsis lyrata	39.64	4.00e-109	389.00
IUUC-Ath-007269	Arabidopsis thaliana	40.18	2.00e-112	400.00
IUUC-Bta-013547	Bos taurus	81.31	0.00e+00	1820.00
IUUC-Bdi-014502	Brachypodium distachyon	39.86	9.00e-112	398.00
IUUC-Bol-015093	Brassica oleracea	40.36	7.00e-113	402.00
IUUC-Bra-016722	Brassica rapa	40.54	7.00e-114	405.00
IUUC-Cel-018447	Caenorhabditis elegans	38.99	0.00e+00	686.00
IUUC-Cja-019855	Callithrix jacchus	81.21	0.00e+00	1792.00
IUUC-Cfa-020066	Canis familiaris	81.59	0.00e+00	1774.00
IUUC-Cpo-021504	Cavia porcellus	81.67	0.00e+00	1826.00
IUUC-Csa-023579	Chlorocebus sabaeus	81.21	0.00e+00	1789.00
IUUC-Cho-024430	Choloepus hoffmanni	71.11	0.00e+00	1291.00
IUUC-Cin-025750	Ciona intestinalis	45.65	0.00e+00	954.00
IUUC-Csv-026016	Ciona savignyi	46.87	0.00e+00	1001.00
IUUC-Dre-028271	Danio rerio	91.77	0.00e+00	1951.00
IUUC-Dno-029054	Dasypus novemcinctus	82.15	0.00e+00	1811.00
IUUC-Dor-030938	Dipodomys ordii	86.09	0.00e+00	1109.00
IUUC-Dme-031602	Drosophila melanogaster	48.39	0.00e+00	968.00
IUUC-Ete-033041	Echinops telfairi	79.26	0.00e+00	866.00
IUUC-Eca-034411	Equus caballus	81.78	0.00e+00	1783.00
IUUC-Eeu-035201	Erinaceus europaeus	77.16	0.00e+00	748.00
IUUC-Fca-036594	Felis catus	80.47	0.00e+00	1761.00
IUUC-Fal-037317	Ficedula albicollis	81.97	0.00e+00	1819.00
IUUC-Gmo-039412	Gadus morhua	90.23	0.00e+00	1971.00
IUUC-Gga-040149	Gallus gallus	85.61	0.00e+00	1842.00
IUUC-Gac-042088	Gasterosteus aculeatus	95.80	0.00e+00	2082.00
IUUC-Gma-043839	Glycine max	40.85	3.00e-113	403.00
IUUC-Ggo-045279	Gorilla gorilla	81.21	0.00e+00	1786.00
IUUC-Hsa-045660	Homo sapiens	81.03	0.00e+00	1783.00
IUUC-Hvu-047770	Hordeum vulgare	37.70	9.00e-110	391.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	73.49	0.00e+00	845.00
IUUC-Lch-050664	Latimeria chalumnae	86.93	0.00e+00	1895.00
IUUC-Lpe-051428	Leersia perrieri	34.66	5.00e-99	355.00
IUUC-Loc-052791	Lepisosteus oculatus	91.33	0.00e+00	1949.00
IUUC-Laf-053902	Loxodonta africana	81.87	0.00e+00	1806.00
IUUC-Mcc-054730	Macaca mulatta	81.12	0.00e+00	1788.00
IUUC-Meu-056527	Macropus eugenii	76.87	0.00e+00	1635.00
IUUC-Mtr-057671	Medicago truncatula	40.50	2.00e-112	400.00
IUUC-Mga-059260	Meleagris gallopavo	85.35	0.00e+00	1840.00
IUUC-Mmr-060804	Microcebus murinus	80.54	0.00e+00	1751.00
IUUC-Mdo-062575	Monodelphis domestica	80.58	0.00e+00	1733.00
IUUC-Mmu-063636	Mus musculus	79.81	0.00e+00	1721.00
IUUC-Mac-064989	Musa acuminata	40.00	3.00e-110	393.00
IUUC-Mpu-066677	Mustela putorius furo	80.54	0.00e+00	1672.00
IUUC-Mlu-067952	Myotis lucifugus	81.85	0.00e+00	1749.00
IUUC-Nle-069153	Nomascus leucogenys	81.12	0.00e+00	1786.00
IUUC-Opr-070554	Ochotona princeps	81.72	0.00e+00	1650.00
IUUC-Ont-071372	Oreochromis niloticus	96.91	0.00e+00	2058.00
IUUC-Oan-073327	Ornithorhynchus anatinus	70.08	0.00e+00	743.00
IUUC-Ocu-074183	Oryctolagus cuniculus	80.09	0.00e+00	1769.00
IUUC-Oba-075006	Oryza barthii	37.40	1.00e-112	400.00
IUUC-Obr-076133	Oryza brachyantha	36.61	2.00e-112	400.00
IUUC-Ogl-077003	Oryza glaberrima	37.40	1.00e-112	400.00
IUUC-Ogu-078947	Oryza glumaepatula	37.91	2.00e-113	403.00
IUUC-Oin-080058	Oryza indica	39.62	7.00e-110	392.00
IUUC-Olo-080475	Oryza longistaminata	37.54	2.00e-113	403.00
IUUC-Ome-081741	Oryza meridionalis	39.22	1.00e-102	368.00
IUUC-Oni-082385	Oryza nivara	37.64	2.00e-113	404.00
IUUC-Opu-083176	Oryza punctata	38.11	3.00e-112	399.00
IUUC-Oru-084554	Oryza rufipogon	35.60	3.00e-100	360.00
IUUC-Osa-085355	Oryza sativa	37.54	2.00e-113	403.00
IUUC-Ola-087337	Oryzias latipes	95.97	0.00e+00	1990.00
IUUC-Oga-088342	Otolemur garnettii	80.39	0.00e+00	1716.00
IUUC-Oar-090234	Ovis aries	80.55	0.00e+00	1786.00
IUUC-Ptr-091661	Pan troglodytes	81.21	0.00e+00	1788.00
IUUC-Pan-092728	Papio anubis	80.95	0.00e+00	1784.00
IUUC-Psi-093251	Pelodiscus sinensis	84.91	0.00e+00	1709.00
IUUC-Pma-094195	Petromyzon marinus	70.92	0.00e+00	1475.00
IUUC-Ppa-095544	Physcomitrella patens	38.20	1.00e-112	401.00
IUUC-Pfo-097472	Poecilia formosa	99.06	0.00e+00	2098.00
IUUC-Pab-098570	Pongo abelii	81.31	0.00e+00	1788.00
IUUC-Pca-100110	Procavia capensis	71.31	0.00e+00	1504.00
IUUC-Ppe-101281	Prunus persica	39.72	6.00e-108	385.00
IUUC-Pva-102887	Pteropus vampyrus	76.75	0.00e+00	1655.00
IUUC-Rno-106028	Rattus norvegicus	77.78	0.00e+00	1640.00
IUUC-Sha-107331	Sarcophilus harrisii	81.25	0.00e+00	1757.00
IUUC-Smo-109488	Selaginella moellendorffii	37.79	2.00e-107	384.00
IUUC-Sit-109811	Setaria italica	39.79	9.00e-110	391.00
IUUC-Sar-113287	Sorex araneus	67.37	7.00e-161	561.00
IUUC-Sbi-114433	Sorghum bicolor	40.29	1.00e-110	394.00
IUUC-Ssc-116103	Sus scrofa	81.67	0.00e+00	1779.00
IUUC-Tgu-117275	Taeniopygia guttata	84.58	0.00e+00	1818.00
IUUC-Tru-118681	Takifugu rubripes	95.04	0.00e+00	2071.00
IUUC-Tsy-118985	Tarsius syrichta	71.08	0.00e+00	831.00
IUUC-Tni-120850	Tetraodon nigroviridis	99.00	0.00e+00	828.00
IUUC-Tca-121770	Theobroma cacao	39.72	4.00e-112	399.00
IUUC-Tae-125466	Triticum aestivum	36.82	9.00e-110	391.00
IUUC-Tur-126086	Triticum urartu	39.79	2.00e-106	380.00
IUUC-Tbe-127461	Tupaia belangeri	77.29	0.00e+00	1632.00
IUUC-Ttr-129269	Tursiops truncatus	81.21	0.00e+00	1756.00
IUUC-Vpa-130523	Vicugna pacos	72.52	3.00e-112	400.00
IUUC-Vvi-131524	Vitis vinifera	39.68	2.00e-110	394.00
IUUC-Xtr-132146	Xenopus tropicalis	82.93	0.00e+00	1833.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence