iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033223

UUCD1 version

UUC-EqC-00933

Ensembl Protein ID

ENSECAP00000005076.1

UniProt Accession

F7E2G5; F7E2G5_HORSE

Protein Name

Uncharacterized protein

Gene Name

PWP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000006090.1	ENSECAT00000007027.1	ENSECAP00000005076.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-24	85.2	499	530
UBD/Beta-Prp	7.20e-57	193.0	290	480

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH++++++l+f +    l+s+s+D t+++WD+
   Q: 499  GHEGPISGLCFnPMkSVLASASWDRTVRLWDM 530
           8**********977778**************7 PP

UBD/Beta-Prp

   S: 12   vitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseD.rtikvwdlstgkcvhtlkghedsvls 99
            +t+ ++++++ ll+tg+++g   ++++ + +l++sls  ++ +++v+++++g++++ g +  + + vw+ ++ ++v + +gh +s +s
   Q: 290  NLTAAAYHKKTHLLVTGFASGIFHLHELPEFNLIHSLSISDQRIASVSINSSGDWIAFGCSGlGQLLVWEWQSESYVLKQQGHFNSMVS 378
           5788999*******************************************************9************************** PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsf 188
           l++sp+g+++v+G++d  ++vw++ +g c+  t+++h++ v++v++  +g ++v++s D+tvr +dl + +  rt+t+    +  ++++
   Q: 379  LAYSPDGQYIVTGGDDGKVKVWNTLSGFCFI-TFTEHSSGVTGVTFTATGYVIVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAV 466
           ******************************9.********************************************************* PP
   S: 189  dsngkelvsgsldg 202
           ds+g+ + +g++d+
   Q: 467  DSSGEIVSAGAQDS 480
           ****9999999996 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

LLSFQFSNLL GTVYRCGNLN FTCDGNSVIS PVGNRVTVFD LKNNKSDTLP LATRYNIKCV 60
GLSPDGRLAI IVDEGGNALL VSLVCRSVLH HFHFKGSVHS VSFSPDGRKF VVTKGNIAQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCTTTCTT TTCAGTTTTC AAATTTGCTG GGGACCGTCT ATAGGTGTGG AAACTTAAAT 60
TTTACCTGTG ATGGCAATTC AGTCATCAGT CCTGTGGGAA ACAGAGTCAC TGTATTTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR023302--Pept_S9A_N
IPR027145--PWP2
IPR011047--Quinoprotein_ADH-like_supfam
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04003--Utp12
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000028--P:ribosomal small subunit assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001932	Ailuropoda melanoleuca	92.08	0.00e+00	1714.00
IUUC-Atr-003033	Amborella trichopoda	40.02	0.00e+00	672.00
IUUC-Apl-003219	Anas platyrhynchos	76.91	0.00e+00	1441.00
IUUC-Aca-004950	Anolis carolinensis	75.59	0.00e+00	1421.00
IUUC-Aly-006213	Arabidopsis lyrata	40.35	0.00e+00	660.00
IUUC-Ath-006593	Arabidopsis thaliana	40.42	0.00e+00	659.00
IUUC-Ago-007916	Ashbya gossypii	43.43	0.00e+00	719.00
IUUC-Acl-008225	Aspergillus clavatus	45.71	0.00e+00	783.00
IUUC-Afl-008390	Aspergillus flavus	45.35	0.00e+00	775.00
IUUC-Afu-009039	Aspergillus fumigatus	45.81	0.00e+00	782.00
IUUC-Ani-009228	Aspergillus nidulans	42.07	0.00e+00	686.00
IUUC-Ang-009663	Aspergillus niger	44.19	0.00e+00	759.00
IUUC-Aor-009923	Aspergillus oryzae	45.35	0.00e+00	775.00
IUUC-Ate-010264	Aspergillus terreus	45.65	0.00e+00	795.00
IUUC-Ame-010790	Astyanax mexicanus	66.18	4.00e-159	553.00
IUUC-Bgr-012066	Blumeria graminis	43.90	0.00e+00	766.00
IUUC-Bta-012399	Bos taurus	93.66	0.00e+00	1687.00
IUUC-Bci-013757	Botrytis cinerea	50.49	4.00e-172	598.00
IUUC-Bdi-015028	Brachypodium distachyon	40.96	0.00e+00	669.00
IUUC-Bol-016521	Brassica oleracea	41.39	0.00e+00	667.00
IUUC-Bra-017096	Brassica rapa	41.12	0.00e+00	666.00
IUUC-Cel-018690	Caenorhabditis elegans	39.42	0.00e+00	642.00
IUUC-Cja-019229	Callithrix jacchus	89.54	0.00e+00	1640.00
IUUC-Cfa-020504	Canis familiaris	91.53	0.00e+00	1714.00
IUUC-Cpo-021574	Cavia porcellus	90.21	0.00e+00	1683.00
IUUC-Cre-022756	Chlamydomonas reinhardtii	42.15	2.00e-150	526.00
IUUC-Csa-023436	Chlorocebus sabaeus	90.44	0.00e+00	1653.00
IUUC-Cin-025397	Ciona intestinalis	57.96	0.00e+00	879.00
IUUC-Csv-026194	Ciona savignyi	49.95	0.00e+00	899.00
IUUC-Cgl-026684	Colletotrichum gloeosporioides	43.86	0.00e+00	716.00
IUUC-Cne-027031	Cryptococcus neoformans	46.15	0.00e+00	813.00
IUUC-Cme-027276	Cyanidioschyzon merolae	30.79	8.00e-109	388.00
IUUC-Dre-027514	Danio rerio	67.70	0.00e+00	1271.00
IUUC-Dno-029191	Dasypus novemcinctus	87.94	0.00e+00	1421.00
IUUC-Dor-030149	Dipodomys ordii	88.20	0.00e+00	1639.00
IUUC-Dse-031260	Dothistroma septosporum	50.70	8.00e-167	580.00
IUUC-Dme-032043	Drosophila melanogaster	46.40	0.00e+00	827.00
IUUC-Ete-033102	Echinops telfairi	87.10	0.00e+00	1036.00
IUUC-Fca-035795	Felis catus	85.25	0.00e+00	1556.00
IUUC-Fal-036830	Ficedula albicollis	76.98	0.00e+00	1438.00
IUUC-Fox-037835	Fusarium oxysporum	43.65	0.00e+00	748.00
IUUC-Fso-038324	Fusarium solani	44.14	0.00e+00	739.00
IUUC-Gmo-039355	Gadus morhua	70.53	0.00e+00	1320.00
IUUC-Ggr-039840	Gaeumannomyces graminis	43.46	0.00e+00	710.00
IUUC-Gga-040907	Gallus gallus	80.56	0.00e+00	924.00
IUUC-Gac-042624	Gasterosteus aculeatus	70.54	0.00e+00	1300.00
IUUC-Gma-043034	Glycine max	40.18	0.00e+00	684.00
IUUC-Hsa-046145	Homo sapiens	90.44	0.00e+00	1677.00
IUUC-Hvu-047416	Hordeum vulgare	40.74	0.00e+00	660.00
IUUC-Itr-049083	Ictidomys tridecemlineatus	88.85	0.00e+00	1670.00
IUUC-Kpa-049150	Komagataella pastoris	43.80	0.00e+00	741.00
IUUC-Lch-049460	Latimeria chalumnae	72.56	0.00e+00	1240.00
IUUC-Lpe-050840	Leersia perrieri	41.12	0.00e+00	669.00
IUUC-Loc-052733	Lepisosteus oculatus	71.35	0.00e+00	1340.00
IUUC-Lma-053277	Leptosphaeria maculans	45.12	0.00e+00	756.00
IUUC-Laf-054294	Loxodonta africana	90.48	0.00e+00	1590.00
IUUC-Mcc-054624	Macaca mulatta	90.71	0.00e+00	1674.00
IUUC-Meu-056665	Macropus eugenii	72.20	0.00e+00	998.00
IUUC-Mor-057288	Magnaporthe oryzae	43.19	0.00e+00	724.00
IUUC-Mpo-057594	Magnaporthe poae	43.72	0.00e+00	708.00
IUUC-Mtr-058700	Medicago truncatula	41.41	0.00e+00	707.00
IUUC-Mla-058846	Melampsora laricipopulina	45.71	0.00e+00	772.00
IUUC-Mga-059207	Meleagris gallopavo	69.71	0.00e+00	1250.00
IUUC-Mvi-060327	Microbotryum violaceum	45.84	0.00e+00	791.00
IUUC-Mmr-061264	Microcebus murinus	91.17	0.00e+00	1623.00
IUUC-Mdo-062327	Monodelphis domestica	83.67	0.00e+00	1558.00
IUUC-Mmu-063542	Mus musculus	89.75	0.00e+00	1635.00
IUUC-Mac-065142	Musa acuminata	42.04	0.00e+00	688.00
IUUC-Mpu-066098	Mustela putorius furo	91.70	0.00e+00	1474.00
IUUC-Mlu-067056	Myotis lucifugus	86.52	0.00e+00	1547.00
IUUC-Nfi-068323	Neosartorya fischeri	45.71	0.00e+00	782.00
IUUC-Ncr-068925	Neurospora crassa	43.48	0.00e+00	776.00
IUUC-Nle-068970	Nomascus leucogenys	89.97	0.00e+00	1664.00
IUUC-Opr-070966	Ochotona princeps	95.09	0.00e+00	652.00
IUUC-Ont-071252	Oreochromis niloticus	72.07	0.00e+00	1327.00
IUUC-Oan-072737	Ornithorhynchus anatinus	78.64	0.00e+00	1464.00
IUUC-Oba-075794	Oryza barthii	39.96	0.00e+00	633.00
IUUC-Obr-076617	Oryza brachyantha	41.17	0.00e+00	669.00
IUUC-Ogl-077022	Oryza glaberrima	41.28	0.00e+00	670.00
IUUC-Ogu-078757	Oryza glumaepatula	33.22	1.00e-128	453.00
IUUC-Oin-079813	Oryza indica	40.83	0.00e+00	665.00
IUUC-Olo-080265	Oryza longistaminata	41.17	0.00e+00	672.00
IUUC-Ome-081494	Oryza meridionalis	40.94	0.00e+00	664.00
IUUC-Oni-082639	Oryza nivara	33.33	6.00e-129	454.00
IUUC-Opu-084005	Oryza punctata	41.50	0.00e+00	682.00
IUUC-Oru-084883	Oryza rufipogon	33.11	9.00e-128	451.00
IUUC-Osa-086158	Oryza sativa	40.79	0.00e+00	665.00
IUUC-Ola-086822	Oryzias latipes	70.85	0.00e+00	1328.00
IUUC-Olu-087741	Ostreococcus lucimarinus	32.29	1.00e-20	91.70
IUUC-Oga-088887	Otolemur garnettii	90.94	0.00e+00	1613.00
IUUC-Oar-090110	Ovis aries	90.34	0.00e+00	1615.00
IUUC-Pan-092808	Papio anubis	90.15	0.00e+00	1674.00
IUUC-Psi-093954	Pelodiscus sinensis	77.90	0.00e+00	1457.00
IUUC-Pno-094922	Phaeosphaeria nodorum	45.62	0.00e+00	771.00
IUUC-Ppa-095678	Physcomitrella patens	42.66	0.00e+00	667.00
IUUC-Pfo-097175	Poecilia formosa	72.55	0.00e+00	1360.00
IUUC-Pab-098155	Pongo abelii	89.88	0.00e+00	1670.00
IUUC-Pop-099635	Populus trichocarpa	48.01	1.00e-166	580.00
IUUC-Pca-100947	Procavia capensis	85.38	0.00e+00	1552.00
IUUC-Ppe-101552	Prunus persica	41.21	0.00e+00	718.00
IUUC-Pva-102744	Pteropus vampyrus	84.62	0.00e+00	1510.00
IUUC-Pgr-103389	Puccinia graminis	45.68	0.00e+00	760.00
IUUC-Ptt-103953	Puccinia triticina	39.80	1.00e-179	623.00
IUUC-Pte-104079	Pyrenophora teres	44.62	0.00e+00	714.00
IUUC-Pyt-104656	Pyrenophora triticirepentis	44.73	0.00e+00	711.00
IUUC-Rno-105502	Rattus norvegicus	89.43	0.00e+00	1674.00
IUUC-Sce-106390	Saccharomyces cerevisiae	44.17	0.00e+00	755.00
IUUC-Sha-107264	Sarcophilus harrisii	78.93	0.00e+00	659.00
IUUC-Sja-107674	Schizosaccharomyces japonicus	42.91	0.00e+00	744.00
IUUC-Spo-108348	Schizosaccharomyces pombe	43.90	0.00e+00	736.00
IUUC-Smo-108982	Selaginella moellendorffii	42.74	0.00e+00	699.00
IUUC-Sit-110304	Setaria italica	41.21	0.00e+00	697.00
IUUC-Sly-111620	Solanum lycopersicum	48.05	2.00e-163	569.00
IUUC-Stu-112877	Solanum tuberosum	42.18	0.00e+00	728.00
IUUC-Sbi-114702	Sorghum bicolor	41.18	0.00e+00	690.00
IUUC-Sre-115129	Sporisorium reilianum	42.81	0.00e+00	702.00
IUUC-Ssc-115931	Sus scrofa	92.13	0.00e+00	760.00
IUUC-Tgu-116787	Taeniopygia guttata	76.56	0.00e+00	1431.00
IUUC-Tru-118218	Takifugu rubripes	70.57	0.00e+00	1313.00
IUUC-Tsy-119401	Tarsius syrichta	91.58	0.00e+00	902.00
IUUC-Tni-120046	Tetraodon nigroviridis	68.96	0.00e+00	1269.00
IUUC-Tca-121685	Theobroma cacao	42.46	0.00e+00	725.00
IUUC-Tre-122154	Trichoderma reesei	44.57	0.00e+00	761.00
IUUC-Tvi-122451	Trichoderma virens	38.02	6.00e-171	594.00
IUUC-Tae-125397	Triticum aestivum	44.54	6.00e-121	428.00
IUUC-Tur-126650	Triticum urartu	40.28	3.00e-178	618.00
IUUC-Tme-127005	Tuber melanosporum	46.21	0.00e+00	775.00
IUUC-Tbe-128102	Tupaia belangeri	90.75	0.00e+00	1002.00
IUUC-Ttr-128259	Tursiops truncatus	92.21	0.00e+00	1613.00
IUUC-Uma-129511	Ustilago maydis	43.05	0.00e+00	701.00
IUUC-Vda-129833	Verticillium dahliae	42.45	0.00e+00	695.00
IUUC-Vvi-131572	Vitis vinifera	41.90	0.00e+00	684.00
IUUC-Xtr-131776	Xenopus tropicalis	56.38	1.00e-120	427.00
IUUC-Xma-133887	Xiphophorus maculatus	72.54	0.00e+00	1318.00
IUUC-Yli-134427	Yarrowia lipolytica	47.89	3.00e-175	608.00
IUUC-Zma-135980	Zea mays	41.41	0.00e+00	682.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence