iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppe-101298

Ensembl Protein ID

EMJ09583

UniProt Accession

M5WK18; M5WK18_PRUPE

Genbank Protein ID

EMJ09583.1

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

KB639090

Gene Name

PRUPE_ppa000549mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PRUPE_ppa000549mg	EMJ09583	EMJ09583

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	4.90e-171	570.0	496	983

Active Site

Position(s)	Description	Evidence
677	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveahees 96
           YD Qi ++G++ q+kl+ +kv+lvG g+lGcEllKnL+l+Gv     g++tv+D+d +e+snl+rqFLfr++++g+ K+ vaa a++ +np  nvea +++
   Q: 496  YDAQISVFGSKLQKKLEDSKVFLVGSGALGCELLKNLALMGVscsnhGKLTVTDDDVIEKSNLSRQFLFRDWNIGQAKSTVAASAAASINPRLNVEALQNR 596
           ***************************************************************************************************** PP
   S: 97   iteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.... 190
           + +++e+++   F ++++vV++aldn+ ar++v+++cl+ ++ l+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+++wa    
   Q: 597  VGPETENVFddtFWENLSVVINALDNVNARLYVDQRCLYFQKALLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWArsef 697
           *******99******************************************************************************************** PP
   S: 191  ........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv......... 274
                   + +n +l++ ++ +++  +   ++ ++++++v + l  e+ e+f+++i +a+ +f+ +++n +kql+  f+ d  t+ ++pfw+         
   Q: 698  egllektpAEVNAYLSKPSEYVTTMRNAGDAQARDTLERVLECLDRERCETFQDCIGWARLKFEDYFSNRVKQLIYTFPEDATTSTGAPFWSapkrfphpl 798
           ********99******************************************************************************************* PP
   S: 275  ................................................sfcsnaealqvpekvekdeevvkasap......lylllralerfekk..kgrk 319
                                                           +f + ++a+ v +  + + + +    +      +  l+ +le  ++k  +g  
   Q: 799  qfsaadpghlhfviaaailraetfgipipdwvrntkkvaeavekvevsEFQPKKDAKIVTDDEATNLTPQ----SlddaqvINELIIKLEHCREKlpPGFR 895
           *********************************8887666666666654444444444333333333322....144446777777777766665448999 PP
   S: 320  pgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           ++ ++fekddd   ++dl++ +an+ra +++i++ +d+ + k iag+iipaiatt+a+  Gl+++E++Kv++g  k e ++n+f ++a+
   Q: 896  MKPIQFEKDDDTnyHMDLIAGLANMRARNYSIPE-VDKLKAKFIAGRIIPAIATTTAMATGLVCLELYKVLDGghKLEDYRNTFANLAL 983
           9*********************************.*************************************************99875 PP

Organism

Prunus persica

Protein Sequence
(Fasta)

MAFSGVFRSL LHYMLPRKRP SEGVVVEEEE DAIVSKNNST SSSSAAASSV KKHRIGHFVA 60
ESTVNSNSLI SNNHGIVERD VPIMALGHSN PSDIDEDLHS RQLAVYGRET MRRLFASNVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTTTT CTGGCGTTTT CCGCAGCTTA CTGCACTATA TGCTTCCAAG AAAGAGACCT 60
AGCGAAGGAG TGGTTGTAGA AGAAGAAGAA GACGCCATTG TGAGCAAGAA CAACAGCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

pper:PRUPE_ppa000549mg

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-006992	Arabidopsis thaliana	81.43	0.00e+00	1706.00
IUUC-Ago-007873	Ashbya gossypii	45.50	0.00e+00	834.00
IUUC-Acl-008181	Aspergillus clavatus	45.09	0.00e+00	815.00
IUUC-Ani-009371	Aspergillus nidulans	45.90	0.00e+00	811.00
IUUC-Ang-009737	Aspergillus niger	45.23	0.00e+00	808.00
IUUC-Bta-012767	Bos taurus	45.86	0.00e+00	885.00
IUUC-Cpo-022526	Cavia porcellus	45.76	0.00e+00	867.00
IUUC-Mla-059176	Melampsora laricipopulina	47.63	0.00e+00	855.00
IUUC-Oar-090068	Ovis aries	45.72	0.00e+00	877.00
IUUC-Pfo-097184	Poecilia formosa	43.94	0.00e+00	843.00
IUUC-Pop-098934	Populus trichocarpa	80.13	0.00e+00	1777.00
IUUC-Pgr-103336	Puccinia graminis	46.19	0.00e+00	815.00
IUUC-Ptt-103939	Puccinia triticina	46.69	0.00e+00	820.00
IUUC-Sly-111237	Solanum lycopersicum	82.63	0.00e+00	1684.00
IUUC-Stu-112001	Solanum tuberosum	83.32	0.00e+00	1704.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence