iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133120

Ensembl Protein ID

ENSXMAP00000008378.1

UniProt Accession

M4A1N4; M4A1N4_XIPMA

Genbank Protein ID

ENSXMAP00000008378

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01033164

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000008358.1	ENSXMAT00000008389.1	ENSXMAP00000008378.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-91	307.4	127	765

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenp........kepkgellkslqklfeelwkskkkavsprellkalkkea 81
           GlkN+gNtC++N+v+QcLsn+  l+e+l   ++k +l++              kge++++l+ l+++lw+ + +     +++++++k+ 
   Q: 127  GLKNHGNTCFLNAVVQCLSNTDLLAEYLGLeRYKMDLRKGRGtgpgaeerRPVKGEVTEQLAGLVRALWTLEYTPLLSVNFKTVVSKYG 215
           9**************************9764555555544334444444456666********************************** PP
   S: 82   eefsgyeqqDaqEflaflldqleeelkk.eknkpkeeeeeedkselsde.............aeekkkkknkslisdlFqgqlksqikc 156
           ++f+g++q+Da Efl +lld+++e++   ++n++k        ++++++              ++++++ ++s++++ Fq q+ks+++c
   Q: 216  SQFRGNSQHDALEFLLWLLDRVHEDVILaSHNNNK--------TKAPEKgpggadevpctdpIPSQQPRAQHSFVQEHFQAQYKSSLTC 296
           **************************442222222........2222222222333566666999************************ PP
   S: 157  lecdnvssreepfldlslpvpgkeetkke............................................................ 185
           ++c ++s++++pfl +slp+p ++++ +                                                             
   Q: 297  PHCLKQSNTFDPFLCISLPIPLRQTRLLCvtlvfstkgqrylrvgmavplfgsvaclrrmvadegklspdqviltevystgfhrsffde 385
           ************************775559*********************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 386  ddltciaendviyafqapplyirggsarisgyhhslpsspyssgpegqrlpssgalsseflnhgvpvkilllvcngagtgqqtvrfgpp 474
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 475  flmredrsiswdqlqqsilsklyylmingahaqnirvlfnirvvggstfhnylspqdgrplhhpavdralklcgsggpphvkliieweh 563
           ***************************************************************************************** PP
   S: 186  ..................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfs 240
                                             +l++c++ +tkee+l  +++++c+ ck++q+   k++l++lP++LilhLkRf  +
   Q: 564  rvkdclfgniheevvkdgdsvrnlqqqhvqqfscTLDECFQLYTKEEQLAPDDAWKCPYCKQLQQGMVKMSLWTLPDILILHLKRF--R 650
           **************************************************************************************..9 PP
   S: 241  eeqksrekinkkvefple.Ldlspfctspeekqke..................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllf 309
           + +++r+k+++ v+fpl  Ld++p+++s++++ ++                  +  Y+L+av++H+G++++GHY+a+++n  +g+W+ +
   Q: 651  QVGEQRNKLTTFVHFPLAgLDMTPHMVSRNNGPHHgplqpgwkhcrrpdlappDFLYNLYAVCNHHGGMHGGHYTAFCRNsVDGQWYSY 739
           9999**********************998888877999999***********9***************************55777**** PP
   S: 310  dDskVtevkeeevleetgstaYvlfYkrr 338
           dDs+V++v+e+ev++   + aY+lfY++r
   Q: 740  DDSTVEPVPEAEVCT---RGAYILFYQKR 765
           ***************...********985 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MEKQSRVKED TKEEKRKERK TKSGKLFRKK SLKSVGSFVN RIMKTLGTFT HFGDGDAQDA 60
EDDDGGFGDG APCTLTASSG MIREDTPPAA AVWDRAAKHP QSTSSSLCAG REKLLYQYGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGAGACA GCCGCCCCAC GCAATCACAG CCCCAGCGTG TGTGTGTGTG TGGGGGGGGG 60
TATTTTCCTG CAGAAGTTGG CGCTGCAGCT GCACTGCCTG TGACAGCGCC GACAGAGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024864	Choloepus hoffmanni	48.67	1.00e-152	533.00
IUUC-Dre-027902	Danio rerio	58.75	0.00e+00	1160.00
IUUC-Dor-030475	Dipodomys ordii	62.16	4.00e-135	476.00
IUUC-Gmo-038903	Gadus morhua	65.53	0.00e+00	876.00
IUUC-Gac-042482	Gasterosteus aculeatus	79.77	0.00e+00	1165.00
IUUC-Ocu-074014	Oryctolagus cuniculus	58.00	0.00e+00	728.00
IUUC-Pfo-096332	Poecilia formosa	94.94	0.00e+00	2090.00
IUUC-Pva-102317	Pteropus vampyrus	56.84	5.00e-177	615.00
IUUC-Sar-113105	Sorex araneus	50.70	7.00e-171	594.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence