iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035893

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02090059

Gene Name

PLAA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000023980.1	ENSFCAT00000029657.1	ENSFCAP00000025179.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.50e-27	92.3	149	179
UBD/Beta-Prp	5.30e-65	219.5	12	302

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v++++  ++ +l+++Gs D+tik+W 
   Q: 149  GHTAAVWAVKIlPEqGLMLTGSADKTIKLWK 179
           8*********99999***************7 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkf.spdksllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgk.....ilvtgseDrtikvwdl 81
           ++l gh+ +v   v+   p +  +++ srd+t+++w  ++++     ++++sgh+++v++v+++p+++     +++tg++D++i++++l
   Q: 12   CSLPGHELDVRGLVCSlYPPGA-FVSVSRDRTTRLWVPDSPNRgfteMHCMSGHSNFVSCVCIIPSSDmyphgLIATGGNDHNICIFSL 99
           6677888888888888566665.888899***********99999******************************************** PP
   S: 82   stgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           +++ ++++lkgh+++v+sls+ +   +l+sGs+d t++vw   +++c+  tl+gh+++v+ v++ p++ l+ +Gs+D+t++lW  k g+
   Q: 100  ESPAPLYILKGHKNTVCSLSSGK-FGTLLSGSWDTTAKVW--LNDKCMM-TLQGHTAAVWAVKILPEQGLMLTGSADKTIKLW--KAGR 182
           **********************9.9***************..9******.*********************************..88** PP
   S: 171  llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllkt 259
           + rt++g h+d v+ l++ s+ +e++s+++d +++ w++ tgec++ + ght+ ++s+ ++pn + +v++++D+s+riW  + g++ +t
   Q: 183  CERTFSG-HEDCVRGLAILSE-TEFLSCANDASIRRWQI-TGECLEVYYGHTNYIYSISVFPNCKDFVTTAEDRSLRIW--KRGECAQT 266
           ******9.*********9996.8****************.***************************************..9******* PP
   S: 260  lqlhnssvisvavlsfgdnvlvlgsedskvniwklkkn 297
           + l+++s+++++v  + +  +v g++d++++++  +++
   Q: 267  IRLPAQSIWCCCV--LANGDIVVGASDGIIRVFTESED 302
           *************..99***************997766 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MASGAARYRL SCSLPGHELD VRGLVCSLYP PGAFVSVSRD RTTRLWVPDS PNRGFTEMHC 60
MSGHSNFVSC VCIIPSSDMY PHGLIATGGN DHNICIFSLE SPAPLYILKG HKNTVCSLSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAGTGCCTT CAGACACATG GAAGGAGGAC GCAGCATTTG TCATTTGTAT GCAGATGTGA 60
CAGTTGAGAT AAATGTTTTA AATCTGAGAA TTGCTTGACA CGTAAGATAT TTTAATTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0016005--F:phospholipase A2 activator activity
GO:0043130--F:ubiquitin binding
GO:0006954--P:inflammatory response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010992--P:ubiquitin homeostasis

KEGG

fca:101091736

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	31.22	1.00e-90	327.00
IUUC-Aml-002125	Ailuropoda melanoleuca	97.62	0.00e+00	1613.00
IUUC-Atr-002554	Amborella trichopoda	30.46	7.00e-95	341.00
IUUC-Apl-004094	Anas platyrhynchos	81.58	0.00e+00	1269.00
IUUC-Aca-004726	Anolis carolinensis	80.78	0.00e+00	1325.00
IUUC-Aly-005961	Arabidopsis lyrata	33.00	3.00e-108	385.00
IUUC-Ath-006639	Arabidopsis thaliana	32.55	2.00e-102	366.00
IUUC-Ago-007772	Ashbya gossypii	30.07	3.00e-81	296.00
IUUC-Acl-008316	Aspergillus clavatus	32.02	3.00e-87	316.00
IUUC-Afl-008532	Aspergillus flavus	32.66	3.00e-90	326.00
IUUC-Afu-008950	Aspergillus fumigatus	32.15	2.00e-90	327.00
IUUC-Ani-009186	Aspergillus nidulans	33.54	1.00e-94	341.00
IUUC-Ang-009575	Aspergillus niger	31.00	2.00e-86	313.00
IUUC-Aor-010086	Aspergillus oryzae	32.66	3.00e-90	326.00
IUUC-Ate-010541	Aspergillus terreus	30.41	2.00e-86	313.00
IUUC-Ame-011633	Astyanax mexicanus	67.79	0.00e+00	1129.00
IUUC-Bgr-012292	Blumeria graminis	30.59	2.00e-94	340.00
IUUC-Bta-013218	Bos taurus	95.35	0.00e+00	1595.00
IUUC-Bci-013876	Botrytis cinerea	39.45	2.00e-91	330.00
IUUC-Bdi-014810	Brachypodium distachyon	33.85	2.00e-106	379.00
IUUC-Bol-016006	Brassica oleracea	32.33	4.00e-106	379.00
IUUC-Bra-017593	Brassica rapa	32.72	4.00e-107	382.00
IUUC-Cel-018703	Caenorhabditis elegans	28.02	2.00e-74	273.00
IUUC-Cja-019270	Callithrix jacchus	94.10	0.00e+00	1565.00
IUUC-Cfa-021262	Canis familiaris	97.12	0.00e+00	1603.00
IUUC-Cpo-021449	Cavia porcellus	87.98	0.00e+00	1425.00
IUUC-Csa-024140	Chlorocebus sabaeus	94.85	0.00e+00	1576.00
IUUC-Cho-024923	Choloepus hoffmanni	93.97	0.00e+00	762.00
IUUC-Cin-025373	Ciona intestinalis	40.12	5.00e-176	611.00
IUUC-Csv-026324	Ciona savignyi	41.84	0.00e+00	653.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	31.74	9.00e-89	321.00
IUUC-Cne-026998	Cryptococcus neoformans	32.14	9.00e-88	318.00
IUUC-Cme-027154	Cyanidioschyzon merolae	30.35	7.00e-59	222.00
IUUC-Dre-028674	Danio rerio	66.12	0.00e+00	1109.00
IUUC-Dno-028966	Dasypus novemcinctus	94.35	0.00e+00	1568.00
IUUC-Dor-030343	Dipodomys ordii	87.94	0.00e+00	905.00
IUUC-Dse-031385	Dothistroma septosporum	30.93	3.00e-83	303.00
IUUC-Dme-032044	Drosophila melanogaster	36.49	9.00e-127	447.00
IUUC-Ete-032506	Echinops telfairi	85.18	0.00e+00	834.00
IUUC-Eca-033547	Equus caballus	96.86	0.00e+00	1608.00
IUUC-Eeu-034462	Erinaceus europaeus	80.71	0.00e+00	677.00
IUUC-Fal-037235	Ficedula albicollis	82.31	0.00e+00	1381.00
IUUC-Fox-037836	Fusarium oxysporum	32.14	5.00e-96	345.00
IUUC-Fso-038251	Fusarium solani	31.38	1.00e-94	340.00
IUUC-Gmo-038648	Gadus morhua	67.16	0.00e+00	978.00
IUUC-Ggr-039867	Gaeumannomyces graminis	30.49	6.00e-84	305.00
IUUC-Gga-040989	Gallus gallus	80.68	0.00e+00	1333.00
IUUC-Gac-041344	Gasterosteus aculeatus	67.83	0.00e+00	1083.00
IUUC-Gma-043067	Glycine max	32.38	9.00e-106	377.00
IUUC-Ggo-045009	Gorilla gorilla	94.10	0.00e+00	1198.00
IUUC-Hsa-046807	Homo sapiens	95.10	0.00e+00	1576.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	95.61	0.00e+00	1587.00
IUUC-Kpa-049134	Komagataella pastoris	34.16	8.00e-92	331.00
IUUC-Lch-049597	Latimeria chalumnae	74.05	0.00e+00	749.00
IUUC-Lpe-050821	Leersia perrieri	31.40	6.00e-98	352.00
IUUC-Loc-051849	Lepisosteus oculatus	73.35	0.00e+00	1224.00
IUUC-Lma-053297	Leptosphaeria maculans	33.72	1.00e-103	370.00
IUUC-Laf-053495	Loxodonta africana	94.24	0.00e+00	1562.00
IUUC-Meu-055983	Macropus eugenii	81.86	0.00e+00	652.00
IUUC-Mor-057006	Magnaporthe oryzae	36.02	3.00e-73	270.00
IUUC-Mpo-057465	Magnaporthe poae	35.98	6.00e-74	272.00
IUUC-Mtr-058374	Medicago truncatula	33.04	6.00e-114	404.00
IUUC-Mla-058895	Melampsora laricipopulina	36.54	5.00e-79	288.00
IUUC-Mvi-060297	Microbotryum violaceum	35.82	1.00e-111	397.00
IUUC-Mmr-060810	Microcebus murinus	90.25	0.00e+00	1464.00
IUUC-Mdo-062671	Monodelphis domestica	88.46	0.00e+00	1451.00
IUUC-Mmu-063536	Mus musculus	93.84	0.00e+00	1534.00
IUUC-Mac-064902	Musa acuminata	31.84	5.00e-100	358.00
IUUC-Mpu-066085	Mustela putorius furo	97.99	0.00e+00	1624.00
IUUC-Mlu-067907	Myotis lucifugus	93.68	0.00e+00	1001.00
IUUC-Nfi-068457	Neosartorya fischeri	32.01	2.00e-73	270.00
IUUC-Ncr-068622	Neurospora crassa	30.58	1.00e-95	344.00
IUUC-Nle-069049	Nomascus leucogenys	94.10	0.00e+00	1546.00
IUUC-Opr-071013	Ochotona princeps	73.66	0.00e+00	648.00
IUUC-Ont-071339	Oreochromis niloticus	70.28	0.00e+00	1168.00
IUUC-Oan-073353	Ornithorhynchus anatinus	83.83	4.00e-113	400.00
IUUC-Ocu-074625	Oryctolagus cuniculus	94.85	0.00e+00	1582.00
IUUC-Oba-075226	Oryza barthii	28.88	1.00e-84	307.00
IUUC-Obr-076875	Oryza brachyantha	33.04	6.00e-110	391.00
IUUC-Ogl-077057	Oryza glaberrima	32.38	1.00e-109	390.00
IUUC-Ogu-078156	Oryza glumaepatula	32.21	1.00e-109	390.00
IUUC-Oin-079373	Oryza indica	32.00	3.00e-108	385.00
IUUC-Olo-080849	Oryza longistaminata	28.89	1.00e-73	271.00
IUUC-Ome-081654	Oryza meridionalis	28.36	2.00e-84	306.00
IUUC-Oni-082221	Oryza nivara	28.98	1.00e-87	317.00
IUUC-Opu-084103	Oryza punctata	29.27	3.00e-85	309.00
IUUC-Oru-084751	Oryza rufipogon	28.13	2.00e-83	303.00
IUUC-Osa-085584	Oryza sativa	31.97	1.00e-108	387.00
IUUC-Ola-086974	Oryzias latipes	69.10	0.00e+00	1162.00
IUUC-Oga-088052	Otolemur garnettii	90.34	0.00e+00	1481.00
IUUC-Oar-089509	Ovis aries	95.02	0.00e+00	1583.00
IUUC-Ptr-090911	Pan troglodytes	95.23	0.00e+00	1579.00
IUUC-Pan-092141	Papio anubis	94.37	0.00e+00	1566.00
IUUC-Psi-093543	Pelodiscus sinensis	83.11	0.00e+00	1285.00
IUUC-Pno-094952	Phaeosphaeria nodorum	32.77	4.00e-97	348.00
IUUC-Ppa-095881	Physcomitrella patens	31.73	2.00e-109	389.00
IUUC-Pfo-096739	Poecilia formosa	68.16	0.00e+00	1147.00
IUUC-Pab-098641	Pongo abelii	95.10	0.00e+00	1574.00
IUUC-Pop-099621	Populus trichocarpa	31.80	1.00e-103	370.00
IUUC-Pca-100599	Procavia capensis	85.25	0.00e+00	1312.00
IUUC-Ppe-101874	Prunus persica	31.59	2.00e-108	387.00
IUUC-Pva-103009	Pteropus vampyrus	92.07	0.00e+00	1286.00
IUUC-Pgr-103260	Puccinia graminis	32.48	7.00e-95	341.00
IUUC-Ptt-103711	Puccinia triticina	32.23	7.00e-93	335.00
IUUC-Pte-104337	Pyrenophora teres	33.03	1.00e-93	337.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	33.42	2.00e-95	343.00
IUUC-Rno-105273	Rattus norvegicus	94.35	0.00e+00	1571.00
IUUC-Sce-106351	Saccharomyces cerevisiae	40.28	2.00e-82	300.00
IUUC-Sha-106758	Sarcophilus harrisii	87.88	0.00e+00	1451.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	40.09	2.00e-95	343.00
IUUC-Spo-108093	Schizosaccharomyces pombe	34.56	6.00e-101	361.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	32.39	1.00e-93	337.00
IUUC-Smo-109368	Selaginella moellendorffii	30.69	2.00e-98	353.00
IUUC-Sit-109699	Setaria italica	33.68	6.00e-110	391.00
IUUC-Sly-111063	Solanum lycopersicum	32.25	3.00e-102	366.00
IUUC-Sar-113199	Sorex araneus	96.24	0.00e+00	820.00
IUUC-Sbi-114745	Sorghum bicolor	32.76	7.00e-103	368.00
IUUC-Sre-115080	Sporisorium reilianum	33.66	1.00e-106	380.00
IUUC-Ssc-115666	Sus scrofa	94.88	0.00e+00	1581.00
IUUC-Tgu-116877	Taeniopygia guttata	81.18	0.00e+00	1368.00
IUUC-Tru-117580	Takifugu rubripes	67.84	0.00e+00	1146.00
IUUC-Tsy-118946	Tarsius syrichta	95.31	0.00e+00	1456.00
IUUC-Tni-119755	Tetraodon nigroviridis	65.57	0.00e+00	1072.00
IUUC-Tca-120977	Theobroma cacao	31.16	1.00e-98	353.00
IUUC-Tre-122217	Trichoderma reesei	32.58	2.00e-97	350.00
IUUC-Tvi-122671	Trichoderma virens	31.47	4.00e-95	342.00
IUUC-Tae-125581	Triticum aestivum	33.50	7.00e-107	381.00
IUUC-Tur-126404	Triticum urartu	23.61	6.00e-21	96.30
IUUC-Tme-126971	Tuber melanosporum	34.44	1.00e-113	404.00
IUUC-Tbe-127858	Tupaia belangeri	76.85	0.00e+00	650.00
IUUC-Ttr-128173	Tursiops truncatus	93.97	0.00e+00	1543.00
IUUC-Uma-129322	Ustilago maydis	33.54	3.00e-107	383.00
IUUC-Vda-129682	Verticillium dahliae	31.96	4.00e-93	335.00
IUUC-Vpa-130607	Vicugna pacos	93.03	0.00e+00	1427.00
IUUC-Vvi-131153	Vitis vinifera	33.46	2.00e-111	396.00
IUUC-Xtr-132208	Xenopus tropicalis	75.22	0.00e+00	1245.00
IUUC-Xma-133098	Xiphophorus maculatus	69.13	0.00e+00	1142.00
IUUC-Yli-134646	Yarrowia lipolytica	39.18	2.00e-95	343.00
IUUC-Zma-135920	Zea mays	31.05	2.00e-93	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence