iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000001782.6	ENSGALT00000002747.5	ENSGALP00000002744.4
ENSGALG00000001782.6	ENSGALT00000051896.1	ENSGALP00000043694.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-24	83.5	149	179
UBD/Beta-Prp	6.50e-60	203.2	30	298

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ +++++  ++ +l+++Gs D+tik+W 
   Q: 149  GHTAAIWAVKIlPEqGLMLTGSADKTIKLWK 179
           8*********99999***************7 PP

UBD/Beta-Prp

   S: 20   pdksllatgsrdgtikvwdvttgkl....lrslsgheaevtavkfspdgk.....ilvtgseDrtikvwdlstgkcvhtlkghedsvls 99
           p++  +++ srd+t ++w  +  +     ++++ gh+++v++v+++p ++     +++tg++D++i+v+ +++  ++++lkgh+++v+s
   Q: 30   PEGG-FVSVSRDRTARLWTPDGLNRgfteMHCMRGHSNFVSCVCIIPPSDlyprgLIATGGNDHNICVFTVDNTAPLYVLKGHTNTVCS 117
           4444.788899********9997779999*******************9999999********************************** PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsf 188
           ls+ +   +l+sGs+d t +vw   ++ c+  tl+gh+++++ v++ p++ l+ +Gs+D+t++lW  k g++ rt  g h+d v+ l++
   Q: 118  LSSGK-FGTLLSGSWDTTCKVW--LNDRCMM-TLQGHTAAIWAVKILPEQGLMLTGSADKTIKLW--KAGRCERTYAG-HEDCVRGLAI 199
           ****9.9***************..9******.*********************************..88*******99.*********9 PP
   S: 189  dsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgd 277
            s++ e++s+s+d +v+ w + +gec++ + ght+ ++sv ++p+ + ++++++D+s+riW  ++g++++t+ l+++sv++++v  +++
   Q: 200  LSEM-EFLSCSNDASVRRWHI-SGECLHVYYGHTNYIYSVSVFPHCKDFITTGEDRSLRIW--KQGECVQTIRLPAQSVWCCCV--LDN 282
           9986.9***************.999************************************..9********************..99* PP
   S: 278  nvlvlgsedskvniwk 293
             +v g++d++++++ 
   Q: 283  DDIVVGASDGIIRVFT 298
           **************96 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MAGDGGVYRL RCSLLGHEQD VRGITRGLFP EGGFVSVSRD RTARLWTPDG LNRGFTEMHC 60
MRGHSNFVSC VCIIPPSDLY PRGLIATGGN DHNICVFTVD NTAPLYVLKG HTNTVCSLSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGTG ATGGCGGCGT CTACCGGCTT CGCTGCTCCC TGCTGGGACA CGAGCAGGAC 60
GTGCGGGGCA TAACGCGAGG CCTCTTCCCC GAGGGCGGCT TCGTGTCCGT GTCCCGGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR016024--ARM-type_fold
IPR033510--PLAA/Doa1/Lub1
IPR015155--PLAA_fam_Ub-bd_PFU
IPR013535--PUL_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS51394--PFU
PS51396--PUL
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09070--PFU
PF08324--PUL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0016005--F:phospholipase A2 activator activity
GO:0043130--F:ubiquitin binding
GO:0006954--P:inflammatory response
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010992--P:ubiquitin homeostasis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000146	Aegilops tauschii	31.80	3.00e-92	332.00
IUUC-Aml-002125	Ailuropoda melanoleuca	80.38	0.00e+00	1344.00
IUUC-Atr-002554	Amborella trichopoda	31.86	1.00e-101	364.00
IUUC-Apl-004094	Anas platyrhynchos	91.16	0.00e+00	1394.00
IUUC-Aca-004726	Anolis carolinensis	81.66	0.00e+00	1358.00
IUUC-Aly-005961	Arabidopsis lyrata	34.12	2.00e-110	392.00
IUUC-Ath-006639	Arabidopsis thaliana	34.07	1.00e-105	377.00
IUUC-Ago-007772	Ashbya gossypii	36.34	2.00e-72	267.00
IUUC-Acl-008316	Aspergillus clavatus	35.67	7.00e-75	275.00
IUUC-Afl-008532	Aspergillus flavus	32.23	4.00e-89	322.00
IUUC-Afu-008950	Aspergillus fumigatus	32.32	4.00e-86	312.00
IUUC-Ani-009186	Aspergillus nidulans	32.87	2.00e-91	330.00
IUUC-Ang-009575	Aspergillus niger	31.89	3.00e-86	313.00
IUUC-Aor-010086	Aspergillus oryzae	32.23	4.00e-89	322.00
IUUC-Ate-010541	Aspergillus terreus	30.96	7.00e-83	301.00
IUUC-Ame-011633	Astyanax mexicanus	65.62	0.00e+00	1075.00
IUUC-Bgr-012292	Blumeria graminis	30.01	1.00e-91	330.00
IUUC-Bta-013218	Bos taurus	79.80	0.00e+00	1342.00
IUUC-Bci-013876	Botrytis cinerea	32.60	2.00e-93	336.00
IUUC-Bdi-014810	Brachypodium distachyon	33.63	5.00e-106	378.00
IUUC-Bol-016006	Brassica oleracea	34.78	2.00e-111	396.00
IUUC-Bra-017593	Brassica rapa	34.59	2.00e-111	396.00
IUUC-Cel-018703	Caenorhabditis elegans	27.80	3.00e-70	259.00
IUUC-Cja-019270	Callithrix jacchus	79.52	0.00e+00	1339.00
IUUC-Cfa-021262	Canis familiaris	80.15	0.00e+00	1341.00
IUUC-Cpo-021449	Cavia porcellus	76.10	0.00e+00	1234.00
IUUC-Csa-024140	Chlorocebus sabaeus	79.77	0.00e+00	1343.00
IUUC-Cho-024923	Choloepus hoffmanni	78.64	0.00e+00	639.00
IUUC-Cin-025373	Ciona intestinalis	39.70	3.00e-174	605.00
IUUC-Csv-026324	Ciona savignyi	42.13	0.00e+00	645.00
IUUC-Cgl-026711	Colletotrichum gloeosporioides	31.44	1.00e-85	310.00
IUUC-Cne-026998	Cryptococcus neoformans	31.36	7.00e-90	325.00
IUUC-Cme-027154	Cyanidioschyzon merolae	32.48	1.00e-58	220.00
IUUC-Dre-028674	Danio rerio	65.24	0.00e+00	1058.00
IUUC-Dno-028966	Dasypus novemcinctus	80.28	0.00e+00	1350.00
IUUC-Dor-030343	Dipodomys ordii	73.52	0.00e+00	762.00
IUUC-Dse-031385	Dothistroma septosporum	30.87	6.00e-85	308.00
IUUC-Dme-032044	Drosophila melanogaster	36.60	7.00e-126	444.00
IUUC-Ete-032506	Echinops telfairi	72.78	0.00e+00	702.00
IUUC-Eca-033547	Equus caballus	80.93	0.00e+00	1357.00
IUUC-Eeu-034462	Erinaceus europaeus	67.70	1.00e-162	566.00
IUUC-Fca-035893	Felis catus	80.68	0.00e+00	1355.00
IUUC-Fal-037235	Ficedula albicollis	90.95	0.00e+00	1518.00
IUUC-Fox-037836	Fusarium oxysporum	31.61	4.00e-96	345.00
IUUC-Fso-038251	Fusarium solani	30.63	4.00e-92	332.00
IUUC-Gmo-038648	Gadus morhua	66.42	0.00e+00	942.00
IUUC-Ggr-039867	Gaeumannomyces graminis	30.02	1.00e-84	307.00
IUUC-Gac-041344	Gasterosteus aculeatus	66.50	0.00e+00	1048.00
IUUC-Gma-043067	Glycine max	33.99	2.00e-108	386.00
IUUC-Ggo-045009	Gorilla gorilla	79.93	0.00e+00	1019.00
IUUC-Hsa-046807	Homo sapiens	79.40	0.00e+00	1337.00
IUUC-Itr-048636	Ictidomys tridecemlineatus	79.77	0.00e+00	1351.00
IUUC-Kpa-049134	Komagataella pastoris	32.98	4.00e-84	305.00
IUUC-Lch-049597	Latimeria chalumnae	69.62	0.00e+00	710.00
IUUC-Lpe-050821	Leersia perrieri	32.41	5.00e-100	358.00
IUUC-Loc-051849	Lepisosteus oculatus	70.69	0.00e+00	1164.00
IUUC-Lma-053297	Leptosphaeria maculans	32.39	7.00e-100	358.00
IUUC-Laf-053495	Loxodonta africana	80.50	0.00e+00	1347.00
IUUC-Meu-055983	Macropus eugenii	76.32	5.00e-174	604.00
IUUC-Mor-057006	Magnaporthe oryzae	35.27	2.00e-72	266.00
IUUC-Mpo-057465	Magnaporthe poae	35.38	5.00e-73	268.00
IUUC-Mtr-058374	Medicago truncatula	35.09	1.00e-118	420.00
IUUC-Mla-058895	Melampsora laricipopulina	36.75	6.00e-78	284.00
IUUC-Mvi-060297	Microbotryum violaceum	35.18	2.00e-111	396.00
IUUC-Mmr-060810	Microcebus murinus	74.62	0.00e+00	1225.00
IUUC-Mdo-062671	Monodelphis domestica	81.16	0.00e+00	1351.00
IUUC-Mmu-063536	Mus musculus	79.27	0.00e+00	1310.00
IUUC-Mac-064902	Musa acuminata	32.45	3.00e-104	372.00
IUUC-Mpu-066085	Mustela putorius furo	80.43	0.00e+00	1356.00
IUUC-Mlu-067907	Myotis lucifugus	80.23	0.00e+00	873.00
IUUC-Nfi-068457	Neosartorya fischeri	31.62	4.00e-69	255.00
IUUC-Ncr-068622	Neurospora crassa	29.81	7.00e-93	334.00
IUUC-Nle-069049	Nomascus leucogenys	78.52	0.00e+00	1310.00
IUUC-Opr-071013	Ochotona princeps	63.39	5.00e-157	548.00
IUUC-Ont-071339	Oreochromis niloticus	68.22	0.00e+00	1118.00
IUUC-Oan-073353	Ornithorhynchus anatinus	80.43	4.00e-108	383.00
IUUC-Ocu-074625	Oryctolagus cuniculus	79.52	0.00e+00	1348.00
IUUC-Oba-075226	Oryza barthii	30.39	1.00e-85	310.00
IUUC-Obr-076875	Oryza brachyantha	33.54	7.00e-109	388.00
IUUC-Ogl-077057	Oryza glaberrima	33.17	8.00e-110	391.00
IUUC-Ogu-078156	Oryza glumaepatula	33.55	7.00e-110	391.00
IUUC-Oin-079373	Oryza indica	32.91	1.00e-108	387.00
IUUC-Olo-080849	Oryza longistaminata	30.61	1.00e-72	267.00
IUUC-Ome-081654	Oryza meridionalis	29.76	3.00e-85	309.00
IUUC-Oni-082221	Oryza nivara	30.14	1.00e-88	320.00
IUUC-Opu-084103	Oryza punctata	30.01	6.00e-88	318.00
IUUC-Oru-084751	Oryza rufipogon	29.52	2.00e-84	306.00
IUUC-Osa-085584	Oryza sativa	32.79	3.00e-108	385.00
IUUC-Ola-086974	Oryzias latipes	67.21	0.00e+00	1129.00
IUUC-Oga-088052	Otolemur garnettii	75.28	0.00e+00	1249.00
IUUC-Oar-089509	Ovis aries	79.23	0.00e+00	1328.00
IUUC-Ptr-090911	Pan troglodytes	79.52	0.00e+00	1339.00
IUUC-Pan-092141	Papio anubis	79.60	0.00e+00	1335.00
IUUC-Psi-093543	Pelodiscus sinensis	84.84	0.00e+00	1320.00
IUUC-Pno-094952	Phaeosphaeria nodorum	33.00	3.00e-95	342.00
IUUC-Ppa-095881	Physcomitrella patens	33.82	2.00e-112	400.00
IUUC-Pfo-096739	Poecilia formosa	66.46	0.00e+00	1090.00
IUUC-Pab-098641	Pongo abelii	79.52	0.00e+00	1339.00
IUUC-Pop-099621	Populus trichocarpa	32.42	2.00e-110	393.00
IUUC-Pca-100599	Procavia capensis	73.19	0.00e+00	1130.00
IUUC-Ppe-101874	Prunus persica	33.00	9.00e-112	397.00
IUUC-Pva-103009	Pteropus vampyrus	77.86	0.00e+00	1099.00
IUUC-Pgr-103260	Puccinia graminis	32.91	5.00e-96	345.00
IUUC-Ptt-103711	Puccinia triticina	32.26	5.00e-90	325.00
IUUC-Pte-104337	Pyrenophora teres	33.33	5.00e-92	332.00
IUUC-Pyt-104475	Pyrenophora triticirepentis	32.90	5.00e-93	335.00
IUUC-Rno-105273	Rattus norvegicus	79.02	0.00e+00	1337.00
IUUC-Sce-106351	Saccharomyces cerevisiae	38.12	3.00e-77	283.00
IUUC-Sha-106758	Sarcophilus harrisii	81.35	0.00e+00	1362.00
IUUC-Sja-107687	Schizosaccharomyces japonicus	37.78	1.00e-89	324.00
IUUC-Spo-108093	Schizosaccharomyces pombe	33.56	1.00e-101	363.00
IUUC-Ssl-108623	Sclerotinia sclerotiorum	33.41	1.00e-94	340.00
IUUC-Smo-109368	Selaginella moellendorffii	32.55	1.00e-103	370.00
IUUC-Sit-109699	Setaria italica	34.72	9.00e-112	397.00
IUUC-Sly-111063	Solanum lycopersicum	33.46	6.00e-107	381.00
IUUC-Sar-113199	Sorex araneus	81.95	0.00e+00	714.00
IUUC-Sbi-114745	Sorghum bicolor	34.01	8.00e-106	377.00
IUUC-Sre-115080	Sporisorium reilianum	32.55	2.00e-97	350.00
IUUC-Ssc-115666	Sus scrofa	79.53	0.00e+00	1336.00
IUUC-Tgu-116877	Taeniopygia guttata	89.32	0.00e+00	1494.00
IUUC-Tru-117580	Takifugu rubripes	66.04	0.00e+00	1103.00
IUUC-Tsy-118946	Tarsius syrichta	81.07	0.00e+00	1263.00
IUUC-Tni-119755	Tetraodon nigroviridis	63.59	0.00e+00	1034.00
IUUC-Tca-120977	Theobroma cacao	32.17	5.00e-106	378.00
IUUC-Tre-122217	Trichoderma reesei	31.50	6.00e-97	348.00
IUUC-Tvi-122671	Trichoderma virens	30.77	6.00e-95	341.00
IUUC-Tae-125581	Triticum aestivum	33.63	1.00e-107	383.00
IUUC-Tur-126404	Triticum urartu	24.93	8.00e-22	98.60
IUUC-Tme-126971	Tuber melanosporum	34.71	1.00e-112	400.00
IUUC-Tbe-127858	Tupaia belangeri	64.49	1.00e-155	543.00
IUUC-Ttr-128173	Tursiops truncatus	78.42	0.00e+00	1301.00
IUUC-Uma-129322	Ustilago maydis	31.71	6.00e-97	348.00
IUUC-Vda-129682	Verticillium dahliae	30.38	4.00e-87	315.00
IUUC-Vpa-130607	Vicugna pacos	78.39	0.00e+00	1230.00
IUUC-Vvi-131153	Vitis vinifera	34.33	2.00e-114	406.00
IUUC-Xtr-132208	Xenopus tropicalis	74.12	0.00e+00	1236.00
IUUC-Xma-133098	Xiphophorus maculatus	67.26	0.00e+00	1092.00
IUUC-Yli-134646	Yarrowia lipolytica	40.04	3.00e-94	339.00
IUUC-Zma-135920	Zea mays	32.71	2.00e-96	347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence