iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116924

Ensembl Protein ID

ENSTGUP00000002320.1

UniProt Accession

H0YVJ9; H0YVJ9_TAEGU

Genbank Protein ID

ENSTGUP00000002320

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01038551

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000002243.1	ENSTGUT00000002341.1	ENSTGUP00000002320.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	3.70e-22	77.9	422	481

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkas 60
           +ee+let+ vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q++ l+k+ + l+d ++ s
   Q: 422  QEEDLETMSVLRAQMEVYCSDFHAERAAREKIHEEKEQLAVQLAYLLKDQQNLEDLGRTS 481
           79**************************************************99988765 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MAPPALNTYT PEEMVQQMKE LITENNELKE AMKLHNQAMK DRYEELSTWR EKQKEEREFY 60
ELKFKEAKQC LQAKCIENEQ LQQQLQSLKE REEGAEMEGM WDSVNMQAAP EKEVRQLKSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCCCC CAGCCCTTAA CACCTACACC CCAGAAGAGA TGGTGCAGCA GATGAAAGAA 60
TTAATTACTG AGAACAATGA GTTAAAAGGT GAATGCACAC ATGTGCTGGT CTTAAAATGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	55.03	3.00e-139	488.00
IUUC-Apl-003812	Anas platyrhynchos	78.20	0.00e+00	749.00
IUUC-Aca-004625	Anolis carolinensis	61.25	3.00e-163	567.00
IUUC-Aly-005781	Arabidopsis lyrata	50.00	5.90e-02	31.60
IUUC-Ame-011116	Astyanax mexicanus	46.50	4.00e-54	205.00
IUUC-Bta-013240	Bos taurus	56.83	2.00e-157	548.00
IUUC-Cja-019911	Callithrix jacchus	59.31	4.00e-156	544.00
IUUC-Cfa-020330	Canis familiaris	56.73	9.00e-148	516.00
IUUC-Cpo-021753	Cavia porcellus	55.62	9.00e-141	493.00
IUUC-Csa-023662	Chlorocebus sabaeus	59.67	2.00e-154	538.00
IUUC-Cho-024574	Choloepus hoffmanni	46.87	8.00e-73	266.00
IUUC-Dre-027720	Danio rerio	40.65	2.00e-87	315.00
IUUC-Dno-029079	Dasypus novemcinctus	56.86	2.00e-136	479.00
IUUC-Dor-030890	Dipodomys ordii	54.51	2.00e-148	518.00
IUUC-Dme-032072	Drosophila melanogaster	30.61	7.00e-06	44.70
IUUC-Ete-032568	Echinops telfairi	57.03	3.00e-134	471.00
IUUC-Eca-033528	Equus caballus	57.04	4.00e-149	521.00
IUUC-Eeu-035219	Erinaceus europaeus	53.69	2.00e-136	478.00
IUUC-Fca-035852	Felis catus	56.41	4.00e-145	507.00
IUUC-Fal-036862	Ficedula albicollis	85.71	0.00e+00	820.00
IUUC-Fso-038171	Fusarium solani	50.00	2.80e+00	25.40
IUUC-Gmo-038735	Gadus morhua	39.85	5.00e-76	278.00
IUUC-Gga-040939	Gallus gallus	78.98	0.00e+00	764.00
IUUC-Gac-041580	Gasterosteus aculeatus	43.21	8.00e-92	330.00
IUUC-Ggo-045034	Gorilla gorilla	53.38	2.00e-137	482.00
IUUC-Hsa-046624	Homo sapiens	59.49	3.00e-157	548.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	51.77	6.00e-134	470.00
IUUC-Lch-049720	Latimeria chalumnae	47.70	6.00e-69	254.00
IUUC-Loc-052185	Lepisosteus oculatus	44.87	1.00e-100	360.00
IUUC-Laf-054079	Loxodonta africana	57.04	6.00e-141	493.00
IUUC-Mcc-055674	Macaca mulatta	60.69	4.00e-156	544.00
IUUC-Meu-056769	Macropus eugenii	70.12	2.00e-62	233.00
IUUC-Mga-060203	Meleagris gallopavo	79.23	0.00e+00	717.00
IUUC-Mmr-061492	Microcebus murinus	58.63	1.00e-145	509.00
IUUC-Mdo-063051	Monodelphis domestica	57.30	1.00e-154	539.00
IUUC-Mmu-063409	Mus musculus	54.98	2.00e-150	525.00
IUUC-Mpu-065907	Mustela putorius furo	53.72	4.00e-140	491.00
IUUC-Mlu-066957	Myotis lucifugus	58.42	2.00e-147	515.00
IUUC-Nle-069973	Nomascus leucogenys	59.13	9.00e-152	530.00
IUUC-Opr-071049	Ochotona princeps	54.36	1.00e-127	449.00
IUUC-Ont-071915	Oreochromis niloticus	42.67	7.00e-93	333.00
IUUC-Oan-072965	Ornithorhynchus anatinus	57.38	3.00e-154	538.00
IUUC-Ocu-074029	Oryctolagus cuniculus	52.31	2.00e-120	425.00
IUUC-Ola-087019	Oryzias latipes	41.11	3.00e-84	305.00
IUUC-Oga-088613	Otolemur garnettii	56.96	6.00e-145	507.00
IUUC-Oar-090386	Ovis aries	57.01	2.00e-156	545.00
IUUC-Ptr-091619	Pan troglodytes	59.13	2.00e-155	542.00
IUUC-Pan-092178	Papio anubis	59.53	7.00e-154	536.00
IUUC-Psi-093214	Pelodiscus sinensis	65.45	1.00e-174	606.00
IUUC-Pfo-096901	Poecilia formosa	40.87	1.00e-83	303.00
IUUC-Pab-097560	Pongo abelii	61.97	5.00e-112	397.00
IUUC-Pca-100853	Procavia capensis	73.01	2.00e-58	219.00
IUUC-Pva-102255	Pteropus vampyrus	55.50	2.00e-129	455.00
IUUC-Rno-105812	Rattus norvegicus	53.68	8.00e-149	520.00
IUUC-Sha-107225	Sarcophilus harrisii	61.73	5.00e-114	403.00
IUUC-Sar-113736	Sorex araneus	56.23	2.00e-88	319.00
IUUC-Ssc-115422	Sus scrofa	56.91	2.00e-151	528.00
IUUC-Tru-117695	Takifugu rubripes	40.54	2.00e-83	302.00
IUUC-Tsy-119090	Tarsius syrichta	52.78	7.00e-76	277.00
IUUC-Tni-120645	Tetraodon nigroviridis	41.03	1.00e-88	320.00
IUUC-Tbe-127970	Tupaia belangeri	66.90	1.00e-94	340.00
IUUC-Ttr-129244	Tursiops truncatus	56.62	8.00e-144	503.00
IUUC-Vpa-130313	Vicugna pacos	56.26	3.00e-136	478.00
IUUC-Xtr-132115	Xenopus tropicalis	42.67	8.00e-92	330.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence