iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134110

Ensembl Protein ID

ENSXMAP00000008755.1

UniProt Accession

M4A2R1; M4A2R1_XIPMA

Genbank Protein ID

ENSXMAP00000008755

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01013670

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000008722.1	ENSXMAT00000008769.1	ENSXMAP00000008755.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.80e-32	108.4	411	442
UBD/Beta-Prp	8.10e-49	166.4	409	687

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+++v+cl+  s+ +ll sGs D+tikvWD+
   Q: 411  GHQGPVWCLCVySTgDLLFSGSSDKTIKVWDT 442
           8*********77667****************6 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdv.ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           + gh+  ++ c+++   ++ll++gs d+tikvwd+ tt k+ ++l+gh++ v a++++ +   l +gs D ti vwd++t + v t+++
   Q: 409  FVGHQG-PVWCLCVYSTGDLLFSGSSDKTIKVWDTcTTYKCQKTLEGHDGIVLALCIQGN--KLYSGSADCTIIVWDIQTLQKVNTIRA 494
           555665.55559999*******************846678899****************9..6************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdl.etgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           h++ v++l +s   ++l sGs  + i+vwd+  t+ +l++ l+g +++v+ +v ++  n l sGs+ +t+++Wd+++ ++++ l+    
   Q: 495  HDNPVCTLVSSH--NVLFSGS-LKAIKVWDIvGTELKLKKELTGLNHWVRALVASQ--NHLYSGSY-QTIKIWDIRSLECVHVLQT-SG 576
           *******99999..9******.9*******7368888888**************99..99*****9.79***************99.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           +svys++++    ++v g + + + +wd++++e vrtl+gh  +v+ +++   p+++ + s+s D+s+r+W +++  +++tl +h+ sv
   Q: 577  GSVYSIAVTN--HHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSV 663
           *********9..8***********************************99888************************************ PP
   S: 268  isvavlsfgdnvlvlgsedskvniwkl 294
           ++ av   ++  l++g+ ds+v++w +
   Q: 664  TALAV---SRGRLFSGAVDSTVKVWTC 687
           ****9...*****************86 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MSSSKTPRYS QYSGGAAAST SISSSPSSPP ADSGVGSMME ATFGPTFSSS GAKAESSSTY 60
KQHRRTPSSS STLTYSPRDD DDGMPPIGTP RRSDSAISIR SLHSESNMSL RSTFSLHEEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAAGAAGA TGTATATATT AGGAGAGGCT TCGCTTTGCT TTGCTTTGCG CAATTTCGAC 60
AGCCACCGAG TCCAGGCTCA CCTCCTCATC CTGAACTATG GATAATGTAG TCCGACTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00400--WD40
PF13445--zf-RING_UBOX

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

KEGG

xma:102218966

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	85.55	0.00e+00	1140.00
IUUC-Apl-004098	Anas platyrhynchos	91.55	0.00e+00	1164.00
IUUC-Aca-004852	Anolis carolinensis	83.06	0.00e+00	920.00
IUUC-Ame-011275	Astyanax mexicanus	86.82	0.00e+00	954.00
IUUC-Bta-013153	Bos taurus	85.78	0.00e+00	1142.00
IUUC-Cja-019243	Callithrix jacchus	84.99	0.00e+00	1102.00
IUUC-Cfa-020036	Canis familiaris	86.07	0.00e+00	1150.00
IUUC-Cpo-022194	Cavia porcellus	86.01	0.00e+00	1143.00
IUUC-Csa-023363	Chlorocebus sabaeus	85.63	0.00e+00	1144.00
IUUC-Cin-025279	Ciona intestinalis	57.19	0.00e+00	786.00
IUUC-Csv-026163	Ciona savignyi	62.21	0.00e+00	760.00
IUUC-Dre-027998	Danio rerio	92.91	0.00e+00	1161.00
IUUC-Dno-029356	Dasypus novemcinctus	84.19	3.00e-118	417.00
IUUC-Dor-030750	Dipodomys ordii	88.23	0.00e+00	1115.00
IUUC-Eca-033671	Equus caballus	72.79	0.00e+00	887.00
IUUC-Eeu-034765	Erinaceus europaeus	94.41	2.00e-160	559.00
IUUC-Fca-035843	Felis catus	86.07	0.00e+00	1153.00
IUUC-Fal-037237	Ficedula albicollis	88.39	0.00e+00	1181.00
IUUC-Gmo-038779	Gadus morhua	86.98	0.00e+00	1079.00
IUUC-Gga-040579	Gallus gallus	87.81	0.00e+00	1175.00
IUUC-Gac-042233	Gasterosteus aculeatus	91.77	0.00e+00	1193.00
IUUC-Gma-042914	Glycine max	30.04	1.00e-19	91.30
IUUC-Ggo-045147	Gorilla gorilla	85.92	0.00e+00	1143.00
IUUC-Hsa-046117	Homo sapiens	85.63	0.00e+00	1144.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	86.36	0.00e+00	1153.00
IUUC-Lch-050593	Latimeria chalumnae	86.79	0.00e+00	1142.00
IUUC-Loc-052444	Lepisosteus oculatus	89.70	0.00e+00	1236.00
IUUC-Laf-053499	Loxodonta africana	84.02	0.00e+00	1094.00
IUUC-Mcc-055038	Macaca mulatta	85.63	0.00e+00	1144.00
IUUC-Meu-056610	Macropus eugenii	83.27	0.00e+00	846.00
IUUC-Mtr-057641	Medicago truncatula	27.43	2.00e-20	94.00
IUUC-Mga-060183	Meleagris gallopavo	87.55	0.00e+00	1167.00
IUUC-Mmr-061133	Microcebus murinus	83.51	0.00e+00	1069.00
IUUC-Mdo-062312	Monodelphis domestica	87.10	0.00e+00	1160.00
IUUC-Mmu-063844	Mus musculus	86.65	0.00e+00	1135.00
IUUC-Mpu-066552	Mustela putorius furo	85.78	0.00e+00	1137.00
IUUC-Mlu-067719	Myotis lucifugus	85.78	0.00e+00	1117.00
IUUC-Nle-070045	Nomascus leucogenys	90.24	0.00e+00	1118.00
IUUC-Opr-070927	Ochotona princeps	88.79	0.00e+00	1126.00
IUUC-Ont-072680	Oreochromis niloticus	92.34	0.00e+00	1232.00
IUUC-Oan-073521	Ornithorhynchus anatinus	95.00	1.00e-52	197.00
IUUC-Ola-087454	Oryzias latipes	94.34	0.00e+00	1255.00
IUUC-Oga-088380	Otolemur garnettii	85.63	0.00e+00	1148.00
IUUC-Oar-089558	Ovis aries	70.11	0.00e+00	890.00
IUUC-Ptr-091606	Pan troglodytes	85.92	0.00e+00	1143.00
IUUC-Pan-092227	Papio anubis	85.63	0.00e+00	1144.00
IUUC-Psi-093853	Pelodiscus sinensis	80.37	0.00e+00	957.00
IUUC-Pma-094541	Petromyzon marinus	81.13	6.00e-155	539.00
IUUC-Pfo-096237	Poecilia formosa	97.68	0.00e+00	1288.00
IUUC-Pab-097589	Pongo abelii	85.78	0.00e+00	1142.00
IUUC-Pca-100375	Procavia capensis	88.41	0.00e+00	1100.00
IUUC-Pva-102434	Pteropus vampyrus	85.78	0.00e+00	1149.00
IUUC-Rno-105443	Rattus norvegicus	86.79	0.00e+00	1140.00
IUUC-Sha-106517	Sarcophilus harrisii	86.83	0.00e+00	1155.00
IUUC-Sly-111122	Solanum lycopersicum	27.27	1.00e-17	84.30
IUUC-Ssc-115990	Sus scrofa	85.49	0.00e+00	1141.00
IUUC-Tgu-117222	Taeniopygia guttata	87.61	0.00e+00	1163.00
IUUC-Tru-118392	Takifugu rubripes	95.13	0.00e+00	1221.00
IUUC-Tni-120220	Tetraodon nigroviridis	94.39	0.00e+00	1209.00
IUUC-Tbe-128045	Tupaia belangeri	97.22	3.00e-158	551.00
IUUC-Ttr-128203	Tursiops truncatus	82.44	0.00e+00	1084.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence