iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041760

UUCD1 version

UUC-GaA-01107

Ensembl Protein ID

ENSGACP00000027452.1

UniProt Accession

G3QC36; G3QC36_GASAC

Protein Name

Uncharacterized protein

Gene Name

cbl (1 of many); CBL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000020763.1	ENSGACT00000027504.1	ENSGACP00000027452.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-06	28.3	364	403

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pC H+++++Cl +w    + +s  + CP Cr
   Q: 364  CKICAENDKD-VKIEPCRHLMCTSCLTAW----Q-ESEGQGCPFCR 403
           99********.******************....5.555555****8 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MAGNPRRGAG LIGLMKDAFQ PHQQPLQPHQ PAVVDKKMVE KCWKLMDKVV RLCQNPKVAL 60
KNSPPYILDL LPDTYQHLRT VLSRYEGKME ILGENEYFRV VMENLTNKTK QTMSLFKEAK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGGAA ATCCGAGGAG GGGCGCCGGT CTCATCGGCT TGATGAAGGA CGCCTTTCAG 60
CCCCACCAGC AGCCTCTGCA GCCTCACCAG CCCGCAGTGG TCGATAAGAA AATGGTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Gmo-039279	Gadus morhua	93.07	0.00e+00	875.00
IUUC-Ont-072133	Oreochromis niloticus	72.62	0.00e+00	1134.00
IUUC-Ola-086885	Oryzias latipes	71.91	0.00e+00	1071.00
IUUC-Pfo-096049	Poecilia formosa	94.36	0.00e+00	950.00
IUUC-Tru-118300	Takifugu rubripes	72.51	0.00e+00	1102.00
IUUC-Tni-119861	Tetraodon nigroviridis	91.18	0.00e+00	911.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence