iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021666

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02011865

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008971.3	ENSCPOT00000009053.2	ENSCPOP00000008060.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.00e-82	276.1	445	947

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 445  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 522
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++ +++ + ++ +l++         +   + +++k+li+++F+g+l++++ cl+c+++s++ e
   Q: 523  QDCSEYLRFLLDRLHEEEKIlkaQSSHKPSDSLGCSEVSLQEGstkaagltETPCTSNSEKTLIERMFGGKLQTHVCCLNCRSTSQKVE 611
           *****************94444444455555555555555544999999988889999999**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  + + +++                                                                       
   Q: 612  AFTDLSLAFCPSPSVEHLsfqdlaslpraqdgglmqasgpspseetvvynpataafvcdsvvneigsppdefhcaestsvsneateifv 700
           *********988866555899******************************************************************** PP
   S: 186  ..............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
                         s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl L+
   Q: 701  nkdvpqkpggentpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLE 789
           ***************************************************************************************99 PP
   S: 261  lspfcts.....peekqke...............................kkkYeLiavvvHsG.slssGHYvayvkn........... 301
           l    t+     +     e                                + Y L++vvvHsG s++sGHY++y++n           
   Q: 790  LPVKRTTsfsslS-----EswsvdvdfndtsenlakklkpsrleepfcpkLVPYLLSSVVVHSGvSSESGHYYSYARNitgtessyemc 873
           9965555244440.....345555566666666666777777888888879************************************** PP
   S: 302  .................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                             +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 874  hqsetlslapsqnrflgrdgpsavieqdletkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 947
           ********99999999999999999988876654666*******************999************986 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MDKILEGLVS SSHPLPLKRV IVRKVVESAE HWLDRAQCEA MFDLTTRLIL EGQDPFQRQV 60
GHQVLEAYAR YHRPEFESFF NKTFVLGLLQ QGYNSLDRKD VAILDYIHNG LKLIMSCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGG CCTGGTGAGC TCTTCGCACC CGCTGCCCCT CAAGCGGGTG 60
ATTGTACGGA AGGTGGTGGA ATCGGCGGAG CACTGGCTGG ACCGGGCGCA GTGCGAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	91.01	0.00e+00	1809.00
IUUC-Apl-003435	Anas platyrhynchos	76.25	0.00e+00	1260.00
IUUC-Aca-004556	Anolis carolinensis	70.90	0.00e+00	1272.00
IUUC-Ame-010616	Astyanax mexicanus	61.87	0.00e+00	1202.00
IUUC-Bta-013544	Bos taurus	90.78	0.00e+00	1773.00
IUUC-Cja-018745	Callithrix jacchus	90.73	0.00e+00	1818.00
IUUC-Cfa-020434	Canis familiaris	87.24	0.00e+00	1732.00
IUUC-Csa-023965	Chlorocebus sabaeus	92.03	0.00e+00	1875.00
IUUC-Cho-024809	Choloepus hoffmanni	81.30	0.00e+00	1206.00
IUUC-Cin-025604	Ciona intestinalis	37.83	4.00e-41	161.00
IUUC-Csv-026333	Ciona savignyi	43.43	7.00e-31	127.00
IUUC-Dre-028338	Danio rerio	61.45	0.00e+00	1212.00
IUUC-Dno-029372	Dasypus novemcinctus	90.40	0.00e+00	1794.00
IUUC-Dor-030752	Dipodomys ordii	88.93	0.00e+00	1241.00
IUUC-Dme-031871	Drosophila melanogaster	29.19	4.00e-44	173.00
IUUC-Ete-032588	Echinops telfairi	78.18	0.00e+00	1084.00
IUUC-Eca-034416	Equus caballus	92.03	0.00e+00	1865.00
IUUC-Eeu-035132	Erinaceus europaeus	71.80	0.00e+00	1332.00
IUUC-Fca-036137	Felis catus	91.36	0.00e+00	1826.00
IUUC-Fal-037297	Ficedula albicollis	75.91	0.00e+00	1446.00
IUUC-Gmo-038727	Gadus morhua	65.20	0.00e+00	1001.00
IUUC-Gga-041091	Gallus gallus	74.38	0.00e+00	1395.00
IUUC-Gac-042082	Gasterosteus aculeatus	61.99	0.00e+00	1121.00
IUUC-Ggo-045376	Gorilla gorilla	86.81	0.00e+00	1698.00
IUUC-Hsa-046444	Homo sapiens	91.84	0.00e+00	1839.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	91.94	0.00e+00	1848.00
IUUC-Lch-050500	Latimeria chalumnae	71.39	0.00e+00	1392.00
IUUC-Loc-052625	Lepisosteus oculatus	64.79	0.00e+00	1272.00
IUUC-Laf-053689	Loxodonta africana	90.95	0.00e+00	1808.00
IUUC-Mcc-055286	Macaca mulatta	92.23	0.00e+00	1845.00
IUUC-Mga-059905	Meleagris gallopavo	74.02	0.00e+00	1220.00
IUUC-Mmr-061397	Microcebus murinus	92.61	0.00e+00	1849.00
IUUC-Mdo-062833	Monodelphis domestica	85.47	0.00e+00	1749.00
IUUC-Mmu-063157	Mus musculus	89.35	0.00e+00	1797.00
IUUC-Mpu-066434	Mustela putorius furo	91.94	0.00e+00	1841.00
IUUC-Mlu-068178	Myotis lucifugus	89.59	0.00e+00	1752.00
IUUC-Nle-070153	Nomascus leucogenys	91.65	0.00e+00	1804.00
IUUC-Ont-072330	Oreochromis niloticus	62.18	0.00e+00	1202.00
IUUC-Oan-072709	Ornithorhynchus anatinus	80.05	0.00e+00	1248.00
IUUC-Ocu-074832	Oryctolagus cuniculus	92.03	0.00e+00	1837.00
IUUC-Ola-087003	Oryzias latipes	54.17	2.00e-43	168.00
IUUC-Oga-088517	Otolemur garnettii	87.76	0.00e+00	1756.00
IUUC-Oar-089472	Ovis aries	87.13	0.00e+00	1700.00
IUUC-Ptr-090996	Pan troglodytes	91.46	0.00e+00	1832.00
IUUC-Pan-091837	Papio anubis	90.18	0.00e+00	1821.00
IUUC-Psi-093236	Pelodiscus sinensis	76.66	0.00e+00	1164.00
IUUC-Pma-094349	Petromyzon marinus	52.95	0.00e+00	957.00
IUUC-Pfo-097193	Poecilia formosa	62.43	0.00e+00	1147.00
IUUC-Pab-098710	Pongo abelii	91.75	0.00e+00	1855.00
IUUC-Pca-100794	Procavia capensis	80.06	0.00e+00	1555.00
IUUC-Pva-102722	Pteropus vampyrus	91.08	0.00e+00	1815.00
IUUC-Rno-105743	Rattus norvegicus	88.68	0.00e+00	1752.00
IUUC-Sha-106563	Sarcophilus harrisii	84.35	0.00e+00	1400.00
IUUC-Sar-113533	Sorex araneus	76.01	0.00e+00	1479.00
IUUC-Ssc-116259	Sus scrofa	82.01	0.00e+00	1532.00
IUUC-Tgu-117475	Taeniopygia guttata	76.05	0.00e+00	1314.00
IUUC-Tru-118623	Takifugu rubripes	62.44	0.00e+00	1135.00
IUUC-Tsy-119250	Tarsius syrichta	89.31	0.00e+00	1400.00
IUUC-Tni-120441	Tetraodon nigroviridis	59.07	0.00e+00	1057.00
IUUC-Tbe-127936	Tupaia belangeri	78.89	0.00e+00	1494.00
IUUC-Ttr-128483	Tursiops truncatus	78.80	0.00e+00	1372.00
IUUC-Vpa-130303	Vicugna pacos	97.00	0.00e+00	1062.00
IUUC-Xtr-132773	Xenopus tropicalis	72.58	0.00e+00	1384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence