iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133007

Ensembl Protein ID

ENSXMAP00000009763.1

UniProt Accession

M4A5L9; M4A5L9_XIPMA

Genbank Protein ID

ENSXMAP00000009763

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01006048

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000009748.1	ENSXMAT00000009777.1	ENSXMAP00000009763.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-75	254.8	40	501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +G+kN+g tCY+NS+LQ+L+++pe+re l++  +e+l   ++k++ g     +  +lq+lf+ l+  ++++ s+++l++++++ ++e  
   Q: 40   CGIKNQGGTCYLNSLLQTLLFTPEFREELFSLGPEELGCLEDKDKPGakvrVIPLELQRLFARLLLVDQQSASTTDLTDSFGWNSSE-- 126
           7******************************99998877665555445566899****************************99987.. PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           g++q+D+qE+ ++l+++le +l                            +++++li++l++g + ++i+c+ec+nvs+r+e+fldl++
   Q: 127  GTNQHDVQELNRILFSALEHSL--------------------------VGTSGSTLIQRLYHGIIVNSIVCKECGNVSQRKEDFLDLTV 189
           **********************..........................7899************************************* PP
   S: 175  pvpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
            v g +     sl+++L ++f++ee +eg+n y c +c ++++a k+ klk+lP+++++ L Rfsf+ +++ r k + ++ fpl+++l+
   Q: 190  CVCGVS-----SLEEALwNMFVEEEWFEGNNLYRCAQCSRLVTAAKSAKLKQLPPFMTMSLLRFSFDFAKCERYKETGRYAFPLTINLR 273
           ******.....9*****9*********************************************************************** PP
   S: 263  pfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.................................................. 301
           pfc++++ ++ ++ +YeL++v++H+G++ +GHY++y+++                                                  
   Q: 274  PFCEQTDAED-SDFTYELFSVIIHKGGCYGGHYHVYIRDidelgqweppeedckpkaqkktkeevkesseqklqednplsiitaiiaqe 361
           *****77776.5***************************************************************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 362  ssksvlldqlgqklmnktgsswskrfrkpygpigkflqshsdvfilvsngtrvalkanppspatdasapseqttnsepsaasdgaasdl 450
           **************************************************************************************999 PP
   S: 302  .............ekgk.WllfdDskVtevkeeevleetg..staYvlfYkr 337
                        +  + W+ ++Ds+Vt+++e+++ ++ +  ++aY+lfY++
   Q: 451  qpegnqkpkpkpeQG-ShWFDLNDSTVTSIRESDIAKQFQgkESAYMLFYRK 501
           999998888876333.36*******************8889*********98 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MFGSLFEEKE DEGFVSTSAT GRTAKGGEEP PPPRGRSNLC GIKNQGGTCY LNSLLQTLLF 60
TPEFREELFS LGPEELGCLE DKDKPGAKVR VIPLELQRLF ARLLLVDQQS ASTTDLTDSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGACATGAA ACATGGCCGC CTACAGTTCG ACTATGGTGT TTCTATTTAC GTTTCGCCTG 60
TTTTCTGTTT TAAGACTGAC AGTGGAAGAA AGAGCTCGGT TTCGAAGTCA TTTTGAGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	47.62	0.00e+00	1014.00
IUUC-Apl-004105	Anas platyrhynchos	48.23	0.00e+00	1129.00
IUUC-Aca-004715	Anolis carolinensis	48.34	0.00e+00	1103.00
IUUC-Ame-011073	Astyanax mexicanus	58.54	0.00e+00	1325.00
IUUC-Bta-012487	Bos taurus	46.67	0.00e+00	1063.00
IUUC-Cja-018937	Callithrix jacchus	47.36	0.00e+00	1084.00
IUUC-Cfa-020645	Canis familiaris	38.95	2.00e-152	533.00
IUUC-Cpo-022160	Cavia porcellus	46.78	0.00e+00	1061.00
IUUC-Csa-023078	Chlorocebus sabaeus	47.14	0.00e+00	1095.00
IUUC-Cho-025013	Choloepus hoffmanni	73.81	5.00e-105	375.00
IUUC-Csv-026193	Ciona savignyi	56.71	1.00e-60	225.00
IUUC-Dre-027416	Danio rerio	61.90	0.00e+00	1510.00
IUUC-Dno-029639	Dasypus novemcinctus	42.92	0.00e+00	832.00
IUUC-Dor-030624	Dipodomys ordii	64.94	6.00e-110	392.00
IUUC-Ete-032626	Echinops telfairi	35.31	3.00e-103	369.00
IUUC-Eca-034208	Equus caballus	47.48	0.00e+00	1092.00
IUUC-Fca-036006	Felis catus	64.93	4.00e-142	497.00
IUUC-Fal-036925	Ficedula albicollis	48.68	0.00e+00	1072.00
IUUC-Gmo-038597	Gadus morhua	65.35	0.00e+00	1387.00
IUUC-Gga-041171	Gallus gallus	47.75	0.00e+00	1105.00
IUUC-Gac-041362	Gasterosteus aculeatus	76.03	0.00e+00	1659.00
IUUC-Ggo-045069	Gorilla gorilla	46.13	0.00e+00	966.00
IUUC-Hsa-046715	Homo sapiens	47.37	0.00e+00	1072.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	45.96	0.00e+00	1032.00
IUUC-Lch-050182	Latimeria chalumnae	46.78	0.00e+00	1016.00
IUUC-Loc-052705	Lepisosteus oculatus	58.91	0.00e+00	1431.00
IUUC-Laf-054132	Loxodonta africana	46.97	0.00e+00	1087.00
IUUC-Mcc-055734	Macaca mulatta	47.29	0.00e+00	1090.00
IUUC-Meu-056135	Macropus eugenii	73.59	4.00e-99	356.00
IUUC-Mga-060092	Meleagris gallopavo	47.67	0.00e+00	1092.00
IUUC-Mmr-061546	Microcebus murinus	45.83	0.00e+00	986.00
IUUC-Mdo-061935	Monodelphis domestica	46.41	0.00e+00	1095.00
IUUC-Mmu-063630	Mus musculus	46.99	0.00e+00	1073.00
IUUC-Mpu-066579	Mustela putorius furo	46.63	0.00e+00	1097.00
IUUC-Mlu-068034	Myotis lucifugus	47.03	0.00e+00	1034.00
IUUC-Nle-069082	Nomascus leucogenys	42.36	0.00e+00	814.00
IUUC-Opr-070953	Ochotona princeps	37.47	1.00e-124	441.00
IUUC-Ont-072435	Oreochromis niloticus	78.32	0.00e+00	1961.00
IUUC-Oan-073339	Ornithorhynchus anatinus	47.37	0.00e+00	1092.00
IUUC-Ocu-073760	Oryctolagus cuniculus	47.85	0.00e+00	1090.00
IUUC-Ola-087015	Oryzias latipes	75.56	0.00e+00	1616.00
IUUC-Oga-088960	Otolemur garnettii	47.14	0.00e+00	1082.00
IUUC-Oar-089853	Ovis aries	46.65	0.00e+00	1079.00
IUUC-Ptr-091093	Pan troglodytes	47.60	0.00e+00	1075.00
IUUC-Pan-091962	Papio anubis	46.63	0.00e+00	1081.00
IUUC-Psi-093691	Pelodiscus sinensis	48.44	0.00e+00	1132.00
IUUC-Pma-094428	Petromyzon marinus	61.51	5.00e-87	314.00
IUUC-Pfo-096983	Poecilia formosa	93.00	0.00e+00	2105.00
IUUC-Pab-097860	Pongo abelii	46.34	0.00e+00	984.00
IUUC-Pca-100514	Procavia capensis	50.86	5.00e-112	399.00
IUUC-Pva-102771	Pteropus vampyrus	46.53	0.00e+00	998.00
IUUC-Rno-105405	Rattus norvegicus	46.90	0.00e+00	1075.00
IUUC-Sha-107376	Sarcophilus harrisii	46.77	0.00e+00	1033.00
IUUC-Ssc-115819	Sus scrofa	39.96	0.00e+00	627.00
IUUC-Tgu-117262	Taeniopygia guttata	47.88	0.00e+00	1125.00
IUUC-Tru-117601	Takifugu rubripes	72.63	0.00e+00	1812.00
IUUC-Tsy-118996	Tarsius syrichta	40.37	0.00e+00	762.00
IUUC-Tni-120682	Tetraodon nigroviridis	65.97	0.00e+00	800.00
IUUC-Tbe-127616	Tupaia belangeri	37.91	2.00e-161	563.00
IUUC-Ttr-129075	Tursiops truncatus	57.74	0.00e+00	649.00
IUUC-Vpa-130108	Vicugna pacos	47.60	0.00e+00	972.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence