iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035731

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02087779

Gene Name

KLHL18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000015477.2	ENSFCAT00000015481.2	ENSFCAP00000014351.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-20	73.0	38	103
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.50e-10	39.5	137	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l++g+ +f+ah+ivLaas ++F+a+f++++ e k ++++++++++p++++al++F Y g l +
   Q: 38   CDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECK-QDEIVMQGMDPSALEALINFAYNGHLAI 103
           9*************************************.************************9875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Nclg+++fA+++ c  L+daa++fi++hF
   Q: 137  PKNCLGVRQFAETMMCAVLYDAANSFIHQHF 167
           68***************************** PP

Organism

Felis catus

Protein Sequence
(Fasta)

MVEDGAEELE DLVHFSVSEL PSRGYGVMEE IRRQGKLCDV TLKIGDHKFS AHRIVLAASI 60
PYFHAMFTND MMECKQDEIV MQGMDPSALE ALINFAYNGH LAIDQQNVQS LLMGASFLQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGAGG ACGGCGCGGA GGAGCTGGAG GATCTGGTGC ACTTCTCCGT GTCCGAGTTG 60
CCTAGTCGCG GCTACGGCGT CATGGAGGAG ATCCGGCGGC AAGGCAAGCT GTGCGACGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

fca:101085787

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001536	Ailuropoda melanoleuca	98.43	0.00e+00	1182.00
IUUC-Apl-003270	Anas platyrhynchos	90.40	0.00e+00	1003.00
IUUC-Aca-005395	Anolis carolinensis	91.33	0.00e+00	1090.00
IUUC-Bta-013481	Bos taurus	96.37	0.00e+00	1165.00
IUUC-Cel-018622	Caenorhabditis elegans	44.84	3.00e-142	498.00
IUUC-Cja-019847	Callithrix jacchus	98.08	0.00e+00	1176.00
IUUC-Cfa-020341	Canis familiaris	99.13	0.00e+00	1188.00
IUUC-Cpo-021613	Cavia porcellus	95.72	0.00e+00	1076.00
IUUC-Csa-023611	Chlorocebus sabaeus	97.74	0.00e+00	1174.00
IUUC-Cho-024605	Choloepus hoffmanni	81.27	8.00e-137	480.00
IUUC-Cin-025289	Ciona intestinalis	54.75	0.00e+00	645.00
IUUC-Dre-028248	Danio rerio	84.07	0.00e+00	1022.00
IUUC-Dno-029609	Dasypus novemcinctus	97.04	0.00e+00	1171.00
IUUC-Dor-030541	Dipodomys ordii	96.09	2.00e-149	521.00
IUUC-Dme-032107	Drosophila melanogaster	55.14	0.00e+00	663.00
IUUC-Eca-033507	Equus caballus	98.50	0.00e+00	1102.00
IUUC-Eeu-034750	Erinaceus europaeus	89.64	0.00e+00	979.00
IUUC-Fal-036959	Ficedula albicollis	90.96	0.00e+00	1056.00
IUUC-Gga-040166	Gallus gallus	92.95	0.00e+00	1106.00
IUUC-Ggo-044853	Gorilla gorilla	97.74	0.00e+00	1173.00
IUUC-Hsa-046437	Homo sapiens	97.39	0.00e+00	1165.00
IUUC-Itr-048529	Ictidomys tridecemlineatus	96.28	0.00e+00	1061.00
IUUC-Lch-050195	Latimeria chalumnae	78.87	0.00e+00	917.00
IUUC-Loc-051787	Lepisosteus oculatus	86.75	0.00e+00	995.00
IUUC-Laf-053489	Loxodonta africana	97.74	0.00e+00	1176.00
IUUC-Mcc-055250	Macaca mulatta	96.89	0.00e+00	1167.00
IUUC-Meu-056871	Macropus eugenii	89.13	0.00e+00	1043.00
IUUC-Mga-059425	Meleagris gallopavo	92.95	0.00e+00	1101.00
IUUC-Mmr-061394	Microcebus murinus	97.75	0.00e+00	1180.00
IUUC-Mdo-062285	Monodelphis domestica	95.72	0.00e+00	1131.00
IUUC-Mmu-063975	Mus musculus	97.75	0.00e+00	1181.00
IUUC-Mpu-066369	Mustela putorius furo	98.78	0.00e+00	1185.00
IUUC-Mlu-067832	Myotis lucifugus	94.95	0.00e+00	1068.00
IUUC-Nle-069338	Nomascus leucogenys	90.45	0.00e+00	1054.00
IUUC-Opr-071035	Ochotona princeps	85.31	0.00e+00	927.00
IUUC-Ont-071440	Oreochromis niloticus	83.36	0.00e+00	981.00
IUUC-Ola-087275	Oryzias latipes	81.99	0.00e+00	968.00
IUUC-Oga-087921	Otolemur garnettii	98.78	0.00e+00	1188.00
IUUC-Oar-089968	Ovis aries	89.46	0.00e+00	1040.00
IUUC-Ptr-091272	Pan troglodytes	97.74	0.00e+00	1173.00
IUUC-Pan-092629	Papio anubis	97.56	0.00e+00	1169.00
IUUC-Psi-093456	Pelodiscus sinensis	94.05	0.00e+00	999.00
IUUC-Pma-094509	Petromyzon marinus	69.03	0.00e+00	798.00
IUUC-Pfo-096450	Poecilia formosa	79.82	0.00e+00	969.00
IUUC-Pab-097917	Pongo abelii	97.56	0.00e+00	1170.00
IUUC-Pca-100330	Procavia capensis	97.32	6.00e-176	610.00
IUUC-Pva-103189	Pteropus vampyrus	98.78	0.00e+00	1186.00
IUUC-Pyt-104758	Pyrenophora triticirepentis	34.94	5.00e-07	47.80
IUUC-Sha-107283	Sarcophilus harrisii	95.58	0.00e+00	1097.00
IUUC-Sar-112989	Sorex araneus	97.36	0.00e+00	1087.00
IUUC-Tgu-117146	Taeniopygia guttata	82.12	0.00e+00	920.00
IUUC-Tru-118132	Takifugu rubripes	82.94	0.00e+00	960.00
IUUC-Tsy-119058	Tarsius syrichta	80.60	9.00e-137	479.00
IUUC-Tni-120892	Tetraodon nigroviridis	80.18	0.00e+00	961.00
IUUC-Tbe-127347	Tupaia belangeri	95.47	0.00e+00	1143.00
IUUC-Ttr-128343	Tursiops truncatus	75.89	0.00e+00	789.00
IUUC-Vpa-130796	Vicugna pacos	85.37	0.00e+00	985.00
IUUC-Xtr-132077	Xenopus tropicalis	83.54	0.00e+00	952.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence