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Tag Content
iUUCD ID IUUC-Mpu-066710
Ensembl Protein ID ENSMPUP00000006153.1
UniProt Accession M3Y4A2; M3Y4A2_MUSPF
Genbank Protein ID ENSMPUP00000006153
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AEYP01062727
Gene Name KMT2B
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMPUG00000006206.1 ENSMPUT00000006261.1 ENSMPUP00000006153.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 3.10e-28 97.7 1080 1133
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++g+++k+l+eCe+Cr+++HpaCl++s ++++ ++++  wiC+ C ++
   Q: 1080 KFCHVCGRKGRGSKHLLECERCRHAYHPACLGPS-YPTRATRKRrhWICSACVRC 1133
           58********************************.88888877777******876 PP
   
Organism Mustela putorius furo
Protein Sequence
(Fasta)
MVQALTELLR RAQAPQAPRS RACEPSTPRR SRGRPPGRPA GPCRKKQQAV VVAEAAVTIP 60
KPEPPPPVVP VKHRTGSWKC KEGPGPGPGT PKRGGQSGRG GRGGRGRGRG GLPLVIKFVS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mpu-066710|E3,PHD|Mustela putorius furo
Please wait for a moment...
Nucleotide Sequence
(Fasta)
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNGGGG CCGGGGCTGG GGCCCAAGCC GTGGCTGCGT GCCGGAGGAG GAGAGCAGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mpu-066710|E3,PHD|Mustela putorius furo
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003882--Pistil_extensin
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC
PRINTS

PR01218--PSTLEXTENSIN
SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0005199--F:structural constituent of cell wall
GO:0008270--F:zinc ion binding
GO:0016458--P:gene silencing
GO:0080182--P:histone H3-K4 trimethylation
GO:0007613--P:memory
GO:0009994--P:oocyte differentiation
GO:0001541--P:ovarian follicle development
GO:0030728--P:ovulation
GO:0051569--P:regulation of histone H3-K4 methylation
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002367 Ailuropoda melanoleuca 97.12 0.00e+00 3312.00
IUUC-Aca-004718 Anolis carolinensis 61.79 0.00e+00 1348.00
IUUC-Ame-010705 Astyanax mexicanus 43.62 0.00e+00 912.00
IUUC-Bta-013578 Bos taurus 93.46 0.00e+00 3206.00
IUUC-Bdi-014882 Brachypodium distachyon 33.33 2.00e-27 117.00
IUUC-Bra-017422 Brassica rapa 33.50 2.00e-27 117.00
IUUC-Cja-019138 Callithrix jacchus 90.69 0.00e+00 3217.00
IUUC-Cfa-020020 Canis familiaris 97.88 0.00e+00 3281.00
IUUC-Cpo-021552 Cavia porcellus 89.07 0.00e+00 3132.00
IUUC-Csa-024216 Chlorocebus sabaeus 92.76 0.00e+00 3242.00
IUUC-Dre-027700 Danio rerio 47.52 0.00e+00 734.00
IUUC-Dno-029583 Dasypus novemcinctus 94.77 0.00e+00 3030.00
IUUC-Dor-030903 Dipodomys ordii 87.96 0.00e+00 2162.00
IUUC-Dme-032023 Drosophila melanogaster 47.28 2.00e-92 335.00
IUUC-Eca-034026 Equus caballus 97.29 0.00e+00 1937.00
IUUC-Eeu-034687 Erinaceus europaeus 93.98 0.00e+00 1144.00
IUUC-Fca-036311 Felis catus 96.24 0.00e+00 3357.00
IUUC-Gmo-039265 Gadus morhua 44.62 0.00e+00 808.00
IUUC-Gac-042202 Gasterosteus aculeatus 47.97 0.00e+00 740.00
IUUC-Ggo-044791 Gorilla gorilla 93.76 0.00e+00 2099.00
IUUC-Hsa-046988 Homo sapiens 92.36 0.00e+00 3144.00
IUUC-Hvu-047762 Hordeum vulgare 36.57 4.00e-20 92.80
IUUC-Itr-048907 Ictidomys tridecemlineatus 91.78 0.00e+00 3313.00
IUUC-Lpe-051476 Leersia perrieri 31.51 4.00e-24 106.00
IUUC-Loc-052252 Lepisosteus oculatus 53.44 0.00e+00 781.00
IUUC-Laf-053703 Loxodonta africana 93.77 0.00e+00 2176.00
IUUC-Mcc-054782 Macaca mulatta 91.28 0.00e+00 2459.00
IUUC-Meu-056046 Macropus eugenii 87.08 0.00e+00 1722.00
IUUC-Mmr-061316 Microcebus murinus 91.91 0.00e+00 2815.00
IUUC-Mdo-062648 Monodelphis domestica 83.88 0.00e+00 1955.00
IUUC-Mmu-063579 Mus musculus 89.10 0.00e+00 3198.00
IUUC-Mac-064935 Musa acuminata 33.33 1.00e-29 125.00
IUUC-Mlu-067559 Myotis lucifugus 91.40 0.00e+00 3260.00
IUUC-Nle-070085 Nomascus leucogenys 89.45 0.00e+00 2151.00
IUUC-Opr-071148 Ochotona princeps 89.28 0.00e+00 3131.00
IUUC-Ont-071626 Oreochromis niloticus 46.09 0.00e+00 887.00
IUUC-Ocu-074475 Oryctolagus cuniculus 89.69 0.00e+00 3118.00
IUUC-Obr-076458 Oryza brachyantha 34.48 5.00e-28 119.00
IUUC-Ogl-077851 Oryza glaberrima 36.26 4.00e-28 119.00
IUUC-Ogu-078706 Oryza glumaepatula 36.26 2.00e-28 120.00
IUUC-Oin-079802 Oryza indica 31.43 4.00e-23 103.00
IUUC-Osa-085421 Oryza sativa 36.26 7.00e-28 119.00
IUUC-Ola-086609 Oryzias latipes 51.05 0.00e+00 756.00
IUUC-Oga-088140 Otolemur garnettii 92.89 0.00e+00 3204.00
IUUC-Oar-089447 Ovis aries 90.94 0.00e+00 2275.00
IUUC-Ptr-090902 Pan troglodytes 92.27 0.00e+00 3159.00
IUUC-Pan-091930 Papio anubis 92.76 0.00e+00 3242.00
IUUC-Ppa-095221 Physcomitrella patens 36.02 7.00e-31 129.00
IUUC-Pfo-096884 Poecilia formosa 45.15 0.00e+00 885.00
IUUC-Pab-098404 Pongo abelii 83.02 0.00e+00 2357.00
IUUC-Pop-099585 Populus trichocarpa 33.70 2.00e-26 114.00
IUUC-Pca-100949 Procavia capensis 82.80 0.00e+00 1260.00
IUUC-Ppe-101920 Prunus persica 32.54 1.00e-27 119.00
IUUC-Pva-102634 Pteropus vampyrus 93.94 0.00e+00 3333.00
IUUC-Rno-105870 Rattus norvegicus 88.59 0.00e+00 3253.00
IUUC-Sit-110552 Setaria italica 34.33 7.00e-29 122.00
IUUC-Sar-113289 Sorex araneus 90.64 0.00e+00 1759.00
IUUC-Ssc-115509 Sus scrofa 94.21 0.00e+00 3304.00
IUUC-Tru-117736 Takifugu rubripes 44.89 0.00e+00 833.00
IUUC-Tca-121624 Theobroma cacao 32.20 9.00e-28 119.00
IUUC-Tae-125629 Triticum aestivum 36.57 4.00e-20 93.20
IUUC-Tbe-127825 Tupaia belangeri 90.21 0.00e+00 1452.00
IUUC-Ttr-128754 Tursiops truncatus 94.83 0.00e+00 1255.00
IUUC-Xtr-132838 Xenopus tropicalis 48.61 0.00e+00 984.00
IUUC-Xma-133119 Xiphophorus maculatus 42.84 0.00e+00 961.00
Created Date 25-Jun-2017

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