iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020200

Ensembl Protein ID

ENSCAFP00000017974.3

UniProt Accession

E2RA21; E2RA21_CANLF

Genbank Protein ID

ENSCAFP00000017974

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03001717

Gene Name

WDTC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000012192.3	ENSCAFT00000019377.3	ENSCAFP00000017974.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.70e-28	95.5	45	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH++ v+cl++   ++ll+sGsdD    vWD+
   Q: 45   GHSGCVNCLEWneKGDLLASGSDDQHTIVWDP 76
           8**********65339***************6 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAKVNITRDL IRRQIKERGA LSFERRYHVT DPFIRRLGLE AELQGHSGCV NCLEWNEKGD 60
LLASGSDDQH TIVWDPLHHK KLLSMHTGHT ANIFSVKFLP HAGDRILITG AADSKVHVHD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAATTAAAT GTGTGTCTTG TGGACCTGGG CTTGGCTGGA ATGCTCAAGG GTCCTGAAGA 60
TCCTTCTATA GCTTCCTGCT GTTGAATCCA TTAAGAGAAG ATGGCAAAAG TCAACATAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50293--TPR_REGION
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00028--TPR
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004857--F:enzyme inhibitor activity
GO:0055082--P:cellular chemical homeostasis
GO:0032869--P:cellular response to insulin stimulus
GO:0006006--P:glucose metabolic process
GO:0001701--P:in utero embryonic development
GO:0035264--P:multicellular organism growth
GO:0045717--P:negative regulation of fatty acid biosynthetic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008361--P:regulation of cell size

KEGG

cfa:487347

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000083	Aegilops tauschii	28.57	3.00e-57	216.00
IUUC-Aml-001699	Ailuropoda melanoleuca	99.85	0.00e+00	1359.00
IUUC-Atr-002509	Amborella trichopoda	31.31	2.00e-50	193.00
IUUC-Apl-003379	Anas platyrhynchos	93.23	0.00e+00	1286.00
IUUC-Aca-005202	Anolis carolinensis	90.44	0.00e+00	1257.00
IUUC-Aly-006475	Arabidopsis lyrata	31.49	6.00e-54	205.00
IUUC-Ath-007666	Arabidopsis thaliana	31.26	3.00e-53	203.00
IUUC-Ani-009263	Aspergillus nidulans	27.35	3.00e-25	110.00
IUUC-Ang-009671	Aspergillus niger	27.32	2.00e-26	115.00
IUUC-Ame-010988	Astyanax mexicanus	81.57	0.00e+00	1005.00
IUUC-Bdi-014100	Brachypodium distachyon	29.28	9.00e-50	191.00
IUUC-Bol-016409	Brassica oleracea	31.53	1.00e-51	198.00
IUUC-Bra-016979	Brassica rapa	31.53	4.00e-52	199.00
IUUC-Cel-018561	Caenorhabditis elegans	32.49	2.00e-34	140.00
IUUC-Cja-019212	Callithrix jacchus	96.61	0.00e+00	1303.00
IUUC-Cpo-021739	Cavia porcellus	98.97	0.00e+00	1353.00
IUUC-Cre-022659	Chlamydomonas reinhardtii	33.85	3.00e-34	140.00
IUUC-Csa-023648	Chlorocebus sabaeus	99.12	0.00e+00	1352.00
IUUC-Cin-025155	Ciona intestinalis	44.56	2.00e-63	236.00
IUUC-Csv-026289	Ciona savignyi	45.94	6.00e-149	520.00
IUUC-Cme-027316	Cyanidioschyzon merolae	27.99	6.00e-26	113.00
IUUC-Dre-028745	Danio rerio	80.41	0.00e+00	1112.00
IUUC-Dno-029403	Dasypus novemcinctus	92.64	0.00e+00	1258.00
IUUC-Dor-030332	Dipodomys ordii	89.25	0.00e+00	1223.00
IUUC-Dme-031811	Drosophila melanogaster	37.50	6.00e-110	391.00
IUUC-Ete-032331	Echinops telfairi	92.13	4.00e-147	514.00
IUUC-Eca-033783	Equus caballus	98.82	0.00e+00	1353.00
IUUC-Eeu-034732	Erinaceus europaeus	95.43	0.00e+00	1298.00
IUUC-Fca-036543	Felis catus	99.85	0.00e+00	1359.00
IUUC-Fal-037245	Ficedula albicollis	92.58	0.00e+00	1298.00
IUUC-Gmo-039346	Gadus morhua	78.68	0.00e+00	1118.00
IUUC-Gga-041034	Gallus gallus	93.08	0.00e+00	1283.00
IUUC-Gac-041297	Gasterosteus aculeatus	79.71	0.00e+00	1110.00
IUUC-Gma-042727	Glycine max	31.62	1.00e-49	191.00
IUUC-Ggo-045309	Gorilla gorilla	99.12	0.00e+00	1352.00
IUUC-Hsa-046622	Homo sapiens	99.12	0.00e+00	1352.00
IUUC-Itr-049052	Ictidomys tridecemlineatus	98.49	0.00e+00	1171.00
IUUC-Lch-049810	Latimeria chalumnae	85.56	0.00e+00	1160.00
IUUC-Lpe-051600	Leersia perrieri	28.51	2.00e-66	246.00
IUUC-Loc-052088	Lepisosteus oculatus	85.42	0.00e+00	1185.00
IUUC-Laf-054097	Loxodonta africana	98.09	0.00e+00	1350.00
IUUC-Mcc-054848	Macaca mulatta	99.12	0.00e+00	1352.00
IUUC-Meu-056022	Macropus eugenii	73.39	0.00e+00	810.00
IUUC-Mtr-057735	Medicago truncatula	30.64	1.00e-46	181.00
IUUC-Mga-059622	Meleagris gallopavo	93.08	0.00e+00	1283.00
IUUC-Mmr-060709	Microcebus murinus	98.38	0.00e+00	1352.00
IUUC-Mdo-062401	Monodelphis domestica	95.73	0.00e+00	1307.00
IUUC-Mmu-063899	Mus musculus	96.61	0.00e+00	1322.00
IUUC-Mac-064840	Musa acuminata	31.50	4.00e-49	189.00
IUUC-Mpu-066268	Mustela putorius furo	99.71	0.00e+00	1356.00
IUUC-Mlu-067211	Myotis lucifugus	98.78	0.00e+00	854.00
IUUC-Nle-070019	Nomascus leucogenys	98.97	0.00e+00	1328.00
IUUC-Opr-071008	Ochotona princeps	98.09	0.00e+00	1349.00
IUUC-Ont-072123	Oreochromis niloticus	81.03	0.00e+00	1137.00
IUUC-Ocu-074166	Oryctolagus cuniculus	98.38	0.00e+00	1353.00
IUUC-Oba-075298	Oryza barthii	29.25	2.00e-43	171.00
IUUC-Obr-076849	Oryza brachyantha	28.75	4.00e-42	166.00
IUUC-Ogl-077515	Oryza glaberrima	29.25	2.00e-43	170.00
IUUC-Ogu-077968	Oryza glumaepatula	29.25	2.00e-39	157.00
IUUC-Oin-079231	Oryza indica	29.17	2.00e-38	154.00
IUUC-Olo-081045	Oryza longistaminata	29.38	4.00e-38	154.00
IUUC-Ome-081395	Oryza meridionalis	29.38	7.00e-38	152.00
IUUC-Oni-082801	Oryza nivara	29.25	3.00e-43	169.00
IUUC-Opu-083585	Oryza punctata	29.33	2.00e-43	170.00
IUUC-Oru-085163	Oryza rufipogon	29.05	3.00e-42	167.00
IUUC-Osa-085550	Oryza sativa	33.60	8.00e-29	120.00
IUUC-Ola-086925	Oryzias latipes	78.53	0.00e+00	1097.00
IUUC-Oga-088095	Otolemur garnettii	97.50	0.00e+00	1351.00
IUUC-Oar-090285	Ovis aries	96.91	0.00e+00	1314.00
IUUC-Ptr-091221	Pan troglodytes	99.12	0.00e+00	1352.00
IUUC-Pan-091771	Papio anubis	99.12	0.00e+00	1352.00
IUUC-Psi-093977	Pelodiscus sinensis	92.05	0.00e+00	1272.00
IUUC-Ppa-095373	Physcomitrella patens	30.59	1.00e-48	188.00
IUUC-Pfo-096640	Poecilia formosa	80.41	0.00e+00	1119.00
IUUC-Pab-098513	Pongo abelii	99.12	0.00e+00	1352.00
IUUC-Pop-098837	Populus trichocarpa	31.03	6.00e-45	176.00
IUUC-Pca-101095	Procavia capensis	89.40	0.00e+00	1199.00
IUUC-Ppe-101507	Prunus persica	30.14	2.00e-48	187.00
IUUC-Pva-102444	Pteropus vampyrus	98.67	0.00e+00	1351.00
IUUC-Rno-105952	Rattus norvegicus	96.47	0.00e+00	1326.00
IUUC-Sha-106614	Sarcophilus harrisii	96.02	0.00e+00	1317.00
IUUC-Smo-108844	Selaginella moellendorffii	32.34	2.00e-45	177.00
IUUC-Sit-110154	Setaria italica	33.44	2.00e-40	161.00
IUUC-Sly-111707	Solanum lycopersicum	31.75	5.00e-49	189.00
IUUC-Sar-113129	Sorex araneus	87.91	0.00e+00	883.00
IUUC-Sbi-113858	Sorghum bicolor	28.22	1.00e-59	224.00
IUUC-Ssc-116275	Sus scrofa	98.97	0.00e+00	1355.00
IUUC-Tgu-117507	Taeniopygia guttata	93.08	0.00e+00	1285.00
IUUC-Tru-117969	Takifugu rubripes	78.68	0.00e+00	1120.00
IUUC-Tsy-119374	Tarsius syrichta	86.99	0.00e+00	863.00
IUUC-Tni-119887	Tetraodon nigroviridis	77.15	0.00e+00	1066.00
IUUC-Tca-121722	Theobroma cacao	32.90	2.00e-49	191.00
IUUC-Tae-124583	Triticum aestivum	30.20	1.00e-42	168.00
IUUC-Tur-125968	Triticum urartu	35.34	2.00e-33	138.00
IUUC-Tme-126910	Tuber melanosporum	34.26	3.00e-24	107.00
IUUC-Tbe-127511	Tupaia belangeri	91.72	4.00e-90	324.00
IUUC-Ttr-128390	Tursiops truncatus	96.68	0.00e+00	1285.00
IUUC-Uma-129509	Ustilago maydis	27.85	1.00e-13	71.60
IUUC-Vpa-130124	Vicugna pacos	59.11	1.00e-147	516.00
IUUC-Vvi-131565	Vitis vinifera	29.08	2.00e-34	140.00
IUUC-Xtr-132290	Xenopus tropicalis	77.45	0.00e+00	1060.00
IUUC-Xma-134025	Xiphophorus maculatus	79.97	0.00e+00	1113.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence