iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134141

Ensembl Protein ID

ENSXMAP00000011177.1

UniProt Accession

M4A9N3; M4A9N3_XIPMA

Genbank Protein ID

ENSXMAP00000011177

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01001463

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000011121.1	ENSXMAT00000011191.1	ENSXMAP00000011177.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.00e-81	272.1	1696	2046
UBD/Alpha-Helix/UBA	5.50e-06	26.4	5	41

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgy 87
           +GlkN g+tCYmN+v Q+L++ p l e++l+     +++ + ++p++++  ++q+lf +l++sk +++ p++++k++k++++e+   
   Q: 1696 VGLKNGGATCYMNAVFQQLYMQPGLPEAFLS-----IED-DTDQPEESVFYQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVR 1776
           6******************************.....544.457899***************************************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           eqqDa Ef++ l+dql+e+l                          kk+  +++ +++Fqg +++q +c++c ++++ree+f+ l+l
   Q: 1777 EQQDAYEFFTSLVDQLDEHL--------------------------KKMGREQIFKNTFQGIYSDQKICKDCPHRYEREETFMALNL 1837
           ********************..........................789999*********************************** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
            v + +     sl+ +L++f++ e leg+n+yycekck+k++++k++ +k+lP vL++hL+Rf f+ e ++++k ++++ fp  L++
   Q: 1838 GVTSCQ-----SLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLCIHLMRFGFDWESGRSIKYDEQIRFPWVLNM 1919
           ******.....9*************************************************************************** PP
   S: 262  spfcts.......................peekqkekkkYeLiavvvHsGslssGHYvayvknekgk....WllfdDskVtevke.e 320
           +p+++s                       p +k++ +++YeL++vvvHsG+++ GHY++++k+++g+    W++f+D+ V+e ++ +
   Q: 1920 EPYTVSgmarqdcsgdgaegrgdgssggsPRKKVTISENYELVGVVVHSGQAHAGHYYSFIKDRRGNargrWYKFNDNVVEEFDMnD 2006
           ******787777777777777777777776666666***************************77777777************9735 PP
   S: 321  evleetg........................staYvlfYkr 337
           e le  +                        ++aY+lfY++
   Q: 2007 ETLE-YEcfggeyrpkvydqsnpypdvrrryWNAYMLFYQK 2046
           5555.4459******************************97 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyL 38
           +e+ +  l  MGF d++ +++aLr a n++++Av++L
   Q: 5    EEQHITTLLCMGFpDPDVIRKALRLAKNDINEAVALL 41
           7899999****************************98 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

METEEEQHIT TLLCMGFPDP DVIRKALRLA KNDINEAVAL LTNESPGLGY GYEPMESGPS 60
TGLGSSGDGE NSGRTGTSGF DPPPAYHDVV DGERSNDENG NCSGGSMEFP TTNLYELESR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGAATTCA CCGTATCACC TGTGTCGGCG CTGTTCTGGG AGAAGCAAAT CGTGACAGGC 60
AGGCTAGCTG CGGCGGCGGA CTGTAAACAT GGCGGCGTGC ACAGCTACAG GGCTGTGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033382--USP24
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00165--UBA

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002266	Ailuropoda melanoleuca	79.62	0.00e+00	3946.00
IUUC-Apl-003203	Anas platyrhynchos	65.63	0.00e+00	3084.00
IUUC-Aca-004396	Anolis carolinensis	77.81	0.00e+00	3937.00
IUUC-Ame-011886	Astyanax mexicanus	88.36	0.00e+00	1852.00
IUUC-Bta-013381	Bos taurus	78.67	0.00e+00	4004.00
IUUC-Cja-018955	Callithrix jacchus	79.16	0.00e+00	3594.00
IUUC-Cfa-020720	Canis familiaris	79.63	0.00e+00	3934.00
IUUC-Cpo-022430	Cavia porcellus	77.48	0.00e+00	2796.00
IUUC-Csa-024180	Chlorocebus sabaeus	79.60	0.00e+00	3795.00
IUUC-Cho-025074	Choloepus hoffmanni	73.31	0.00e+00	1580.00
IUUC-Dre-027696	Danio rerio	87.92	0.00e+00	4472.00
IUUC-Dno-029307	Dasypus novemcinctus	76.80	0.00e+00	3906.00
IUUC-Dor-030889	Dipodomys ordii	77.29	0.00e+00	3778.00
IUUC-Ete-032294	Echinops telfairi	80.60	0.00e+00	1623.00
IUUC-Eca-033823	Equus caballus	76.03	0.00e+00	3731.00
IUUC-Eeu-035178	Erinaceus europaeus	72.52	0.00e+00	1769.00
IUUC-Fca-035444	Felis catus	79.53	0.00e+00	3898.00
IUUC-Fal-037555	Ficedula albicollis	79.62	0.00e+00	3929.00
IUUC-Gmo-038587	Gadus morhua	92.59	0.00e+00	2913.00
IUUC-Gga-041231	Gallus gallus	79.23	0.00e+00	4031.00
IUUC-Gac-041584	Gasterosteus aculeatus	94.46	0.00e+00	2911.00
IUUC-Ggo-044502	Gorilla gorilla	78.46	0.00e+00	3985.00
IUUC-Hsa-045851	Homo sapiens	78.66	0.00e+00	3996.00
IUUC-Itr-048746	Ictidomys tridecemlineatus	76.02	0.00e+00	1222.00
IUUC-Lch-049999	Latimeria chalumnae	74.37	0.00e+00	3722.00
IUUC-Loc-051767	Lepisosteus oculatus	86.53	0.00e+00	4366.00
IUUC-Laf-054139	Loxodonta africana	78.50	0.00e+00	3998.00
IUUC-Mcc-055217	Macaca mulatta	78.72	0.00e+00	4002.00
IUUC-Meu-056659	Macropus eugenii	68.88	0.00e+00	1861.00
IUUC-Mga-059267	Meleagris gallopavo	79.82	0.00e+00	3954.00
IUUC-Mmr-060971	Microcebus murinus	77.57	0.00e+00	3930.00
IUUC-Mdo-061925	Monodelphis domestica	79.69	0.00e+00	3954.00
IUUC-Mmu-064019	Mus musculus	78.63	0.00e+00	4064.00
IUUC-Mpu-066652	Mustela putorius furo	78.76	0.00e+00	4023.00
IUUC-Mlu-067518	Myotis lucifugus	79.48	0.00e+00	3909.00
IUUC-Nle-069763	Nomascus leucogenys	79.46	0.00e+00	3898.00
IUUC-Opr-071031	Ochotona princeps	73.71	0.00e+00	3585.00
IUUC-Ont-072136	Oreochromis niloticus	93.31	0.00e+00	4743.00
IUUC-Ocu-073880	Oryctolagus cuniculus	78.22	0.00e+00	4005.00
IUUC-Ola-086544	Oryzias latipes	92.21	0.00e+00	4528.00
IUUC-Oga-088695	Otolemur garnettii	78.53	0.00e+00	4024.00
IUUC-Oar-089401	Ovis aries	79.42	0.00e+00	3898.00
IUUC-Ptr-091657	Pan troglodytes	79.56	0.00e+00	3918.00
IUUC-Pan-092394	Papio anubis	78.76	0.00e+00	4002.00
IUUC-Psi-093813	Pelodiscus sinensis	80.17	0.00e+00	3929.00
IUUC-Pma-094698	Petromyzon marinus	52.55	1.00e-132	466.00
IUUC-Pfo-096811	Poecilia formosa	99.20	0.00e+00	5016.00
IUUC-Pab-097814	Pongo abelii	78.61	0.00e+00	3999.00
IUUC-Pca-101135	Procavia capensis	74.33	0.00e+00	1774.00
IUUC-Pva-102334	Pteropus vampyrus	75.56	0.00e+00	3808.00
IUUC-Rno-105040	Rattus norvegicus	78.74	0.00e+00	4038.00
IUUC-Sha-106658	Sarcophilus harrisii	79.62	0.00e+00	3949.00
IUUC-Sar-113153	Sorex araneus	75.66	0.00e+00	1863.00
IUUC-Ssc-115641	Sus scrofa	79.21	0.00e+00	3772.00
IUUC-Tgu-117467	Taeniopygia guttata	79.11	0.00e+00	2848.00
IUUC-Tru-118074	Takifugu rubripes	82.67	0.00e+00	3980.00
IUUC-Tsy-119165	Tarsius syrichta	79.27	0.00e+00	1869.00
IUUC-Tni-119923	Tetraodon nigroviridis	78.99	0.00e+00	3726.00
IUUC-Tbe-127910	Tupaia belangeri	74.29	0.00e+00	1556.00
IUUC-Ttr-128218	Tursiops truncatus	78.28	0.00e+00	3896.00
IUUC-Vpa-130090	Vicugna pacos	82.62	0.00e+00	1482.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence