• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-045965
Ensembl Protein ID ENSP00000322142.6
UniProt Accession Q8WYH8; A8K1P3; Q53NU6; Q57Z54; Q9BS30; ING5_HUMAN
Genbank Protein ID AAL68979.1; BAB85078.1; BAF82647.1; AAX82019.1; AAY14921.1; AAH05370.1; AAH71899.1
Protein Name Inhibitor of growth protein 5; p28ING5
Genbank Nucleotide ID AF189286; AK074422; AK289958; AC114730; AC133528; BC005370; BC071899
Gene Name ING5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000168395.15 ENST00000636051.1 ENSP00000490767.1
ENSG00000168395.15 ENST00000313552.10 ENSP00000322142.6
ENSG00000168395.15 ENST00000445620.5 ENSP00000416878.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Protein 3D Structure
PDBMMDB
Disease-associated Variation
OMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtPHOSIDA
BioGRID
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 8.60e-09 37.1 187 234
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 187  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 234
           69*.*******99..*********99***********...999997.******87 PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator.
 Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Through chromatin acetylation it may regulate DNA replication and may function as a transcriptional coactivator.
Protein Sequence
(Fasta)
MATAMYLEHY LDSIENLPCE LQRNFQLMRE LDQRTEDKKA EIDILAAEYI STVKTLSPDQ 60
RVERLQKIQN AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKDKMEGSDF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045965|E3,PHD|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCGCGGGCT GGACGGCCGG AGACGCGGGG TCAGGGCGCG GACGAGGGGA GCGCAGGGTC 60
GGAGGGGCTC CCGGACGCTG CCCGCCCAGC GTCGGCTCTC GTTGGCCCCT GGCTGCGCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045965|E3,PHD|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0010--Activator
KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0488--Methylation
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF12998--ING
SMART

SM01408--ING
SM00249--PHD
Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0035064--F:methylated histone binding
GO:0008270--F:zinc ion binding
GO:0006260--P:DNA replication
GO:0043966--P:histone H3 acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045926--P:negative regulation of growth
GO:0043065--P:positive regulation of apoptotic process
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006473--P:protein acetylation
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0006351--P:transcription, DNA-templated
KEGG hsa:84289
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002381 Ailuropoda melanoleuca 98.25 2.00e-112 398.00
IUUC-Atr-002906 Amborella trichopoda 33.06 7.00e-34 137.00
IUUC-Apl-003516 Anas platyrhynchos 89.22 2.00e-94 338.00
IUUC-Aca-005009 Anolis carolinensis 86.13 3.00e-108 384.00
IUUC-Ame-011879 Astyanax mexicanus 76.76 9.00e-102 362.00
IUUC-Bta-012590 Bos taurus 96.48 2.00e-114 404.00
IUUC-Cja-019518 Callithrix jacchus 98.75 2.00e-125 441.00
IUUC-Cfa-020620 Canis familiaris 98.33 6.00e-128 449.00
IUUC-Cpo-022085 Cavia porcellus 97.88 3.00e-118 417.00
IUUC-Csa-023421 Chlorocebus sabaeus 100.00 2.00e-122 431.00
IUUC-Dre-027588 Danio rerio 75.62 9.00e-102 362.00
IUUC-Eca-033493 Equus caballus 95.59 1.00e-115 408.00
IUUC-Fca-035635 Felis catus 95.45 1.00e-55 209.00
IUUC-Fal-036998 Ficedula albicollis 89.13 3.00e-109 387.00
IUUC-Fox-037925 Fusarium oxysporum 59.62 2.00e-19 90.10
IUUC-Gmo-039035 Gadus morhua 76.35 5.00e-98 350.00
IUUC-Gga-040578 Gallus gallus 90.42 3.00e-118 417.00
IUUC-Gac-042172 Gasterosteus aculeatus 74.69 1.00e-100 358.00
IUUC-Loc-052725 Lepisosteus oculatus 82.08 1.00e-99 355.00
IUUC-Mcc-055455 Macaca mulatta 99.13 2.00e-114 404.00
IUUC-Mtr-058089 Medicago truncatula 32.51 2.00e-35 142.00
IUUC-Mga-059312 Meleagris gallopavo 89.11 6.00e-95 339.00
IUUC-Mmr-061351 Microcebus murinus 97.36 2.00e-110 392.00
IUUC-Mdo-062282 Monodelphis domestica 96.25 1.00e-116 412.00
IUUC-Mmu-063201 Mus musculus 94.58 1.00e-119 421.00
IUUC-Mac-064625 Musa acuminata 34.29 2.00e-37 149.00
IUUC-Mpu-066302 Mustela putorius furo 98.33 8.00e-121 426.00
IUUC-Mlu-068192 Myotis lucifugus 97.08 1.00e-120 425.00
IUUC-Ont-072055 Oreochromis niloticus 76.25 5.00e-97 347.00
IUUC-Oan-073652 Ornithorhynchus anatinus 96.05 1.00e-113 401.00
IUUC-Ocu-073871 Oryctolagus cuniculus 96.27 2.00e-121 427.00
IUUC-Ola-087103 Oryzias latipes 75.62 8.00e-94 336.00
IUUC-Oga-088066 Otolemur garnettii 87.35 3.00e-102 364.00
IUUC-Ptr-091665 Pan troglodytes 100.00 2.00e-122 431.00
IUUC-Pan-091875 Papio anubis 100.00 2.00e-122 431.00
IUUC-Psi-093904 Pelodiscus sinensis 93.43 8.00e-102 362.00
IUUC-Pfo-096981 Poecilia formosa 76.35 2.00e-97 348.00
IUUC-Pva-102282 Pteropus vampyrus 90.00 3.00e-121 427.00
IUUC-Rno-105646 Rattus norvegicus 94.17 4.00e-119 420.00
IUUC-Sha-107031 Sarcophilus harrisii 95.22 2.00e-109 388.00
IUUC-Smo-109441 Selaginella moellendorffii 35.08 9.00e-41 159.00
IUUC-Tgu-116837 Taeniopygia guttata 87.88 1.00e-108 385.00
IUUC-Tru-117974 Takifugu rubripes 75.62 8.00e-94 336.00
IUUC-Tni-120024 Tetraodon nigroviridis 75.93 2.00e-87 315.00
IUUC-Vvi-131487 Vitis vinifera 33.76 6.00e-34 137.00
IUUC-Xtr-132189 Xenopus tropicalis 83.26 5.00e-108 383.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved