iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-119804

UUCD1 version

UUC-TeN-00437

Ensembl Protein ID

ENSTNIP00000019593.1

UniProt Accession

H3DGE9; H3DGE9_TETNG

Protein Name

Uncharacterized protein

Gene Name

WDSUB1 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000016494.1	ENSTNIT00000019823.1	ENSTNIP00000019593.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-35	120.0	11	44
E3 activity/RING/U-box	9.70e-25	86.7	399	465
UBD/Beta-Prp	7.20e-51	173.3	140	319

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtgvl 35
           Htd+v+c+af +  +l+++s+D+ti+v+D+ ++  
   Q: 11   HTDEVSCCAFsP-SRLATSSGDKTIRVYDTADFSE 44
           **********75.79**************987765 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqaw 68
           vp+eflCpI+  lM+dPv++++G++y+r+sI+ wl+ ++kt+P+t+ pl+ + l+Pn +l+  i +w
   Q: 399  VPDEFLCPITRALMKDPVIAADGYSYERASIQSWLSGKNKTSPMTNLPLQTTILTPNRSLKTAIRRW 465
           8****************************************************************** PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk........ilvtgseDrtikvwdls.......t 83
            sv+   +fsp ++++++g++ g ik+wd++   ll++   h+ +vt+++f p+ +         l+++++D  +++w+l        +
   Q: 140  ASVVA-CCFSPCSQMFVSGCTHGDIKLWDADFRLLLAEKNAHDLGVTCCSFAPTFNvdgccaefRLASCGQDSRVNIWSLTqrdgsvcA 227
           34444.699*********************************************************************7777777788* PP
   S: 84   gkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...... 166
            k +htl+ +++ vls++fs +g+ ++sGs d+ + v++ ++g+ l+ tl++hd+ v+ v+++p    +++Gs Dr v++W++      
   Q: 228  LKLLHTLTSQSAPVLSCAFSSDGELVASGSVDKSVAVYEANQGTLLH-TLTQHDRYVTAVAFSPVMPWVATGSMDRSVKVWSIgdagss 315
           ***********************************************.*********************************99655555 PP
   S: 167  ...k 167
              +
   Q: 316  vgkP 319
           5551 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

SMALVASLQR HTDEVSCCAF SPSRLATSSG DKTIRVYDTA DFSELRFSPL SGHGYGVHCC 60
CFSACGAHLL SCSTDGLVLV WSSGTGAVTA RLEHPGRSPL RVCALAPDSS LLLAGASDGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCATGGCGC TGGTGGCGAG CCTCCAGCGC CACACGGACG AGGTGAGCTG CTGCGCCTTC 60
TCCCCGTCTC GGCTCGCCAC CTCGTCCGGG GACAAAACCA TCCGGGTTTA CGACACCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00536--SAM_1
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bol-015799	Brassica oleracea	44.30	6.00e-17	81.30
IUUC-Gac-042617	Gasterosteus aculeatus	71.31	0.00e+00	645.00
IUUC-Meu-055962	Macropus eugenii	44.89	2.00e-108	385.00
IUUC-Ont-071447	Oreochromis niloticus	73.63	0.00e+00	650.00
IUUC-Obr-076354	Oryza brachyantha	50.70	7.00e-18	85.10
IUUC-Ogu-078012	Oryza glumaepatula	50.00	5.00e-18	86.70
IUUC-Oin-080024	Oryza indica	50.00	5.00e-18	86.70
IUUC-Pfo-096832	Poecilia formosa	68.97	0.00e+00	652.00
IUUC-Tru-117674	Takifugu rubripes	82.37	0.00e+00	811.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence