iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134322

Ensembl Protein ID

ENSXMAP00000011421.1

UniProt Accession

M4AAC7; M4AAC7_XIPMA

Genbank Protein ID

ENSXMAP00000011421

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01018835

Gene Name

WDSUB1 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000011399.1	ENSXMAT00000011435.1	ENSXMAP00000011421.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.70e-26	91.5	407	478
E3 adaptor/Cullin RING/DCX/DWD	3.90e-32	109.0	11	41
UBD/Beta-Prp	6.40e-52	176.6	140	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
            p eflCpI+ elM+dPv++++G++y+r+sIe+w+  ++kt+P+t+ pl+ + l+Pn +l+  i +w ++n+
   Q: 407  APNEFLCPITTELMKDPVIAADGYSYERESIERWIGGKNKTSPMTNLPLQTTLLTPNRSLKMAITRWKSTNK 478
           799*****************************************************************9986 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrt 32
           Htd+++c+afs   lv+Gs D+t++v+++ +
   Q: 11   HTDEISCCAFSQSALVTGSADKTLRVYSTAD 41
           **********4369*************9766 PP

UBD/Beta-Prp

   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...........ilvtgseDrtikvwdls...... 82
           + i +  fsp +++++tg+++g +k+wd +   ll++   h+ +vt+++f p+ k            l+++++D ++k+w +s      
   Q: 140  ASIVACSFSPCSQVFVTGCTQGDLKLWDDHISLLLAQKDAHDLGVTCCSFAPHFKigelkdscmelRLASCGQDSLLKIWIVSqregav 228
           45556789*********************************************************99*************666667777 PP
   S: 83   .tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.... 166
            t   +h+l+g+ + vls++fs++g+ +vsGs d+ + +++ + g+ l+ +l++hd+ v+ v+++p   l+++Gs Dr v++W++    
   Q: 229  wTMMLLHILTGQAAPVLSCAFSADGELVVSGSVDKSVTIYNANLGTLLH-ILKQHDRYVTAVALSPAYGLMATGSMDRSVNVWKIgaae 316
           7************************************************.****************99****************96666 PP
   S: 167  .............k 167
                         
   Q: 317  sqqvpcqgrklpgH 330
           55555555555553 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MVSLIHTIRD HTDEISCCAF SQSALVTGSA DKTLRVYSTA DFKEFPFSPL TGHGYGVHRC 60
CFSSCGSYLL SCSTDGSIIV WSSETGELLS AVEHPGRSPL RVCALAPDSC LLLAGACDGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCTCTT TAATTCATAC AATTCGAGAT CATACAGACG AGATCAGCTG CTGTGCCTTC 60
TCTCAGTCTG CTCTGGTGAC CGGATCAGCT GATAAAACTC TCCGGGTGTA TAGCACGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	51.87	3.00e-146	511.00
IUUC-Apl-003529	Anas platyrhynchos	49.38	2.00e-141	496.00
IUUC-Cja-018743	Callithrix jacchus	51.87	2.00e-145	508.00
IUUC-Cfa-021197	Canis familiaris	51.87	2.00e-146	512.00
IUUC-Cpo-022279	Cavia porcellus	51.66	9.00e-144	503.00
IUUC-Cho-025083	Choloepus hoffmanni	40.10	2.00e-77	282.00
IUUC-Cin-025786	Ciona intestinalis	36.73	8.00e-81	294.00
IUUC-Ete-032405	Echinops telfairi	51.29	3.00e-99	354.00
IUUC-Fca-035482	Felis catus	51.87	5.00e-146	511.00
IUUC-Fal-036976	Ficedula albicollis	42.30	4.00e-105	375.00
IUUC-Gga-040561	Gallus gallus	50.00	2.00e-141	496.00
IUUC-Gac-042617	Gasterosteus aculeatus	71.49	0.00e+00	684.00
IUUC-Ggo-045503	Gorilla gorilla	51.87	2.00e-144	505.00
IUUC-Hsa-045910	Homo sapiens	51.87	9.00e-145	506.00
IUUC-Mcc-055679	Macaca mulatta	52.28	5.00e-145	507.00
IUUC-Meu-055962	Macropus eugenii	43.98	5.00e-108	384.00
IUUC-Mga-059652	Meleagris gallopavo	50.10	5.00e-143	501.00
IUUC-Mpu-066422	Mustela putorius furo	52.28	5.00e-146	510.00
IUUC-Mlu-067250	Myotis lucifugus	51.14	8.00e-142	496.00
IUUC-Ont-071447	Oreochromis niloticus	77.43	0.00e+00	694.00
IUUC-Oga-088388	Otolemur garnettii	52.28	7.00e-146	510.00
IUUC-Ptr-090616	Pan troglodytes	51.36	4.00e-142	497.00
IUUC-Pan-091769	Papio anubis	51.14	6.00e-98	350.00
IUUC-Pfo-096832	Poecilia formosa	92.96	0.00e+00	886.00
IUUC-Pab-098139	Pongo abelii	50.38	2.00e-111	395.00
IUUC-Pva-102286	Pteropus vampyrus	51.66	6.00e-141	493.00
IUUC-Tgu-116769	Taeniopygia guttata	49.58	1.00e-141	496.00
IUUC-Tru-117674	Takifugu rubripes	68.24	0.00e+00	683.00
IUUC-Tsy-119595	Tarsius syrichta	43.10	3.00e-91	328.00
IUUC-Tni-119804	Tetraodon nigroviridis	68.57	0.00e+00	642.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence