iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000091521.3	ENSDART00000173493.1	ENSDARP00000142956.1
ENSDARG00000091521.3	ENSDART00000126424.2	ENSDARP00000106543.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.00e-16	59.6	32	85

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvi...ekeeqdegWlkgvkelegkrGlfPenFv 59
            +l+dyea+ +deLtl+kGd v+v+   ++ + degW+ g  + ++k G+fP+n+v
   Q: 32   TALFDYEAAGKDELTLRKGDLVEVLsldSEISGDEGWWAG--KVNNKVGIFPSNYV 85
           79***********************999999*********..8************9 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MEPLKNIFSR GTLWKNLDQQ TQKGSFSNPV WTALFDYEAA GKDELTLRKG DLVEVLSLDS 60
EISGDEGWWA GKVNNKVGIF PSNYVSFKPS GYGKSGVVAP PVVSALEPQP VEFCELSLQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCCGC TGAAGAATAT CTTCTCCCGC GGGACGCTGT GGAAGAACCT GGACCAGCAG 60
ACTCAGAAGG GGAGTTTCAG CAATCCCGTG TGGACCGCTC TGTTCGATTA TGAGGCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004706--F:JUN kinase kinase kinase activity
GO:0007257--P:activation of JUN kinase activity
GO:0007017--P:microtubule-based process
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011785	Astyanax mexicanus	78.83	0.00e+00	808.00
IUUC-Gac-042299	Gasterosteus aculeatus	72.32	0.00e+00	738.00
IUUC-Lch-049724	Latimeria chalumnae	67.56	0.00e+00	713.00
IUUC-Loc-052497	Lepisosteus oculatus	78.64	4.00e-173	600.00
IUUC-Ont-071274	Oreochromis niloticus	73.01	0.00e+00	765.00
IUUC-Ola-086581	Oryzias latipes	76.74	0.00e+00	793.00
IUUC-Pfo-096248	Poecilia formosa	70.78	0.00e+00	782.00
IUUC-Tru-118036	Takifugu rubripes	74.71	0.00e+00	698.00
IUUC-Tni-120577	Tetraodon nigroviridis	70.24	0.00e+00	753.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence