iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021931

Ensembl Protein ID

ENSCPOP00000007446.2

UniProt Accession

H0VC00; H0VC00_CAVPO

Genbank Protein ID

ENSCPOP00000007446

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02035648

Gene Name

STXBP5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008283.3	ENSCPOT00000008358.2	ENSCPOP00000007446.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.80e-11	41.7	17	48

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf..sdtllvsGsdDgtikvWDlrtgv 34
            v  l+f  +++ lvs++ D t+++W+lr+ +
   Q: 17   AVLQLQFlvNEGALVSAGSDDTLHLWNLRQKR 48
           4888999977799***************9865 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

LGRPGVDCYC QHESGAAVLQ LQFLVNEGAL VSAGSDDTLH LWNLRQKRPA ILHSLKFNRE 60
RITYCHLPFQ SKWLYVGTER GNTHIVNIES FILSGYVIMW NKAIELSTKT HPGPVVHLSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGGGAGAC CTGGTGTTGA TTGTTACTGC CAACATGAAA GTGGTGCAGC AGTCTTGCAG 60
CTCCAATTCT TGGTTAATGA GGTAAGGGTA TTTTTTTGAC TACTTACAAC TCATAATACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013905--Lgl_C_dom
IPR013577--LLGL2
IPR001388--Synaptobrevin
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50892--V_SNARE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08596--Lgl_C
PF08366--LLGL
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0042593--P:glucose homeostasis
GO:0046676--P:negative regulation of insulin secretion
GO:0050714--P:positive regulation of protein secretion
GO:0017157--P:regulation of exocytosis
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003824	Anas platyrhynchos	76.78	0.00e+00	1628.00
IUUC-Aca-004971	Anolis carolinensis	75.18	0.00e+00	1582.00
IUUC-Ame-011870	Astyanax mexicanus	58.95	0.00e+00	1267.00
IUUC-Bta-013516	Bos taurus	91.01	0.00e+00	1954.00
IUUC-Cja-019607	Callithrix jacchus	90.93	0.00e+00	1852.00
IUUC-Cfa-020684	Canis familiaris	90.64	0.00e+00	1938.00
IUUC-Csa-024071	Chlorocebus sabaeus	91.83	0.00e+00	2061.00
IUUC-Cho-025086	Choloepus hoffmanni	87.43	0.00e+00	1875.00
IUUC-Dre-028232	Danio rerio	67.79	0.00e+00	1367.00
IUUC-Dno-029242	Dasypus novemcinctus	90.55	0.00e+00	1966.00
IUUC-Dor-030660	Dipodomys ordii	83.85	0.00e+00	1789.00
IUUC-Ete-033006	Echinops telfairi	78.89	0.00e+00	1020.00
IUUC-Eeu-034943	Erinaceus europaeus	97.57	0.00e+00	776.00
IUUC-Fal-036915	Ficedula albicollis	81.03	0.00e+00	1795.00
IUUC-Gga-040529	Gallus gallus	83.67	0.00e+00	1827.00
IUUC-Gac-042416	Gasterosteus aculeatus	67.21	0.00e+00	1436.00
IUUC-Ggo-044575	Gorilla gorilla	91.47	0.00e+00	2055.00
IUUC-Hsa-045781	Homo sapiens	91.74	0.00e+00	2061.00
IUUC-Lch-050258	Latimeria chalumnae	76.60	0.00e+00	1404.00
IUUC-Loc-051905	Lepisosteus oculatus	70.22	0.00e+00	1105.00
IUUC-Laf-053669	Loxodonta africana	89.36	0.00e+00	1934.00
IUUC-Mcc-055188	Macaca mulatta	91.74	0.00e+00	2060.00
IUUC-Meu-056246	Macropus eugenii	68.76	0.00e+00	906.00
IUUC-Mmr-061273	Microcebus murinus	84.80	0.00e+00	1889.00
IUUC-Mdo-062223	Monodelphis domestica	87.56	0.00e+00	1832.00
IUUC-Mmu-063800	Mus musculus	90.64	0.00e+00	2011.00
IUUC-Mlu-067278	Myotis lucifugus	90.37	0.00e+00	1998.00
IUUC-Nle-069733	Nomascus leucogenys	91.65	0.00e+00	2060.00
IUUC-Opr-070840	Ochotona princeps	72.39	0.00e+00	998.00
IUUC-Ocu-074214	Oryctolagus cuniculus	91.56	0.00e+00	1986.00
IUUC-Ola-087301	Oryzias latipes	70.05	0.00e+00	1457.00
IUUC-Oga-089148	Otolemur garnettii	88.81	0.00e+00	1953.00
IUUC-Oar-090261	Ovis aries	90.81	0.00e+00	1924.00
IUUC-Ptr-090697	Pan troglodytes	91.74	0.00e+00	2061.00
IUUC-Pan-092899	Papio anubis	91.76	0.00e+00	2055.00
IUUC-Psi-093249	Pelodiscus sinensis	81.01	0.00e+00	1744.00
IUUC-Pfo-096605	Poecilia formosa	66.60	0.00e+00	1276.00
IUUC-Pab-097774	Pongo abelii	85.57	0.00e+00	1594.00
IUUC-Pop-099276	Populus trichocarpa	25.28	8.00e-07	49.70
IUUC-Pva-102704	Pteropus vampyrus	81.83	0.00e+00	1717.00
IUUC-Rno-105297	Rattus norvegicus	91.10	0.00e+00	2002.00
IUUC-Sha-107086	Sarcophilus harrisii	82.53	0.00e+00	1748.00
IUUC-Sly-111338	Solanum lycopersicum	25.84	5.00e-11	62.00
IUUC-Stu-112417	Solanum tuberosum	25.84	7.00e-11	61.60
IUUC-Tgu-117382	Taeniopygia guttata	80.78	0.00e+00	1631.00
IUUC-Tru-118317	Takifugu rubripes	69.44	0.00e+00	1459.00
IUUC-Tsy-119322	Tarsius syrichta	82.75	0.00e+00	1247.00
IUUC-Ttr-129239	Tursiops truncatus	90.00	0.00e+00	1914.00
IUUC-Vpa-130524	Vicugna pacos	84.40	0.00e+00	1751.00
IUUC-Xtr-132634	Xenopus tropicalis	72.45	0.00e+00	1606.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence