iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134210

Ensembl Protein ID

ENSXMAP00000012126.1

UniProt Accession

M4ACD2; M4ACD2_XIPMA

Genbank Protein ID

ENSXMAP00000012126

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01022562

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000012096.1	ENSXMAT00000012142.1	ENSXMAP00000012126.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.00e-12	47.7	381	425
E3 adaptor/Cullin RING/DCX/DWD	1.80e-30	103.8	174	208
UBD/Beta-Prp	1.30e-46	159.2	139	384

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
            +w+++++  SLqh CR+a rr l++q++   ++L +P  L+dYL y+
   Q: 381  HFWEAPRSIASLQHMCRMALRRVLTTQQV---EALAIPTPLQDYLTYR 425
           69************************999...**************96 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           Htd v++l f +d   +lvs+s+D+t++vWDl+++
   Q: 174  HTDVVRDLTFaPDgsLMLVSASRDKTLRVWDLKDD 208
           ***********7767889*************9887 PP

UBD/Beta-Prp

   S: 16   vkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsf 102
            kf +d+ llatg  +g+ik+wdv +gkll  l +h++ v++++f pdg+ +lv++s+D+t++vwdl+ +g +v +l+gh++ v + sf
   Q: 139  FKFGQDQLLLATGLNNGRIKIWDVYSGKLLLNLMDHTDVVRDLTFAPDGSlMLVSASRDKTLRVWDLKdDGNMVKVLRGHQNWVHCSSF 227
           67899999*****************************************9999**************9799****************** PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl............tggh 179
           sp+++ l s ++ + + +w++++ + ++  l+gh+  v + +++pdg ll+++s+D+ v +Wd   +++l +l             g++
   Q: 228  SPDSSILCSVGAGKAVFIWNMDKFTLIR-KLEGHHNDVVSCEFSPDGALLATASYDTRVIVWDHHKATILLELghlfpppspifaGGAN 315
           **99***********************9.9999999999999******************************99**********98889 PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWd 250
           ++ v+s+sf ++g++++s+ +d+ v++w++++     + ++  +n ++ +fs ++  l+ g+ Dgs+ +W 
   Q: 316  DRWVRSVSFCPDGRHIASITDDRFVRFWSIEER--APQAIASLSNGLCCAFSAEGSVLAAGTRDGSVHFWE 384
           999***************************877..78999999***************************3 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MASFPDCVNE NDLDKAKFIG ELLVPVAPFD QKSGREAWTV AFAPNGSYFA WSQGHRIVRL 60
IPWNKCLKSF SLSAGEEGTN PTSPRHLSRQ NSDGGVTIPL ADEPREHTID CGDIVWGLAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTTTTCCC TTCGGTCGGT GCCCTAATTT AGATGGCCAG CTTCCCAGAT TGTGTAAATG 60
AAAATGATCT AGGTAAGTAG TTTGTGGCTC TATTTAACTC AGGACAGTGT TACGCAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR001496--SOCS_box
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50225--SOCS
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07525--SOCS_box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00253--SOCS
SM00969--SOCS_box
SM00320--WD40

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

KEGG

xma:102230402

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001635	Ailuropoda melanoleuca	72.77	0.00e+00	644.00
IUUC-Apl-003903	Anas platyrhynchos	73.06	0.00e+00	640.00
IUUC-Aca-005214	Anolis carolinensis	62.65	8.00e-163	566.00
IUUC-Ame-011740	Astyanax mexicanus	82.90	0.00e+00	746.00
IUUC-Bta-013475	Bos taurus	73.24	0.00e+00	649.00
IUUC-Cja-019053	Callithrix jacchus	73.58	0.00e+00	660.00
IUUC-Cfa-020103	Canis familiaris	73.24	0.00e+00	649.00
IUUC-Cpo-022438	Cavia porcellus	72.54	0.00e+00	656.00
IUUC-Csa-024062	Chlorocebus sabaeus	73.47	0.00e+00	666.00
IUUC-Cho-024334	Choloepus hoffmanni	66.20	2.00e-161	561.00
IUUC-Cin-025590	Ciona intestinalis	39.65	2.00e-77	282.00
IUUC-Csv-026023	Ciona savignyi	40.76	6.00e-78	284.00
IUUC-Dre-028089	Danio rerio	82.90	0.00e+00	746.00
IUUC-Dno-029436	Dasypus novemcinctus	76.00	2.00e-156	545.00
IUUC-Dor-031107	Dipodomys ordii	68.31	1.00e-169	589.00
IUUC-Ete-032326	Echinops telfairi	74.15	0.00e+00	631.00
IUUC-Eca-033401	Equus caballus	73.24	0.00e+00	648.00
IUUC-Eeu-034520	Erinaceus europaeus	71.83	0.00e+00	650.00
IUUC-Fca-036386	Felis catus	72.54	0.00e+00	644.00
IUUC-Fal-036616	Ficedula albicollis	70.63	2.00e-179	621.00
IUUC-Gmo-039335	Gadus morhua	80.87	0.00e+00	689.00
IUUC-Gga-040856	Gallus gallus	72.77	0.00e+00	654.00
IUUC-Gac-042140	Gasterosteus aculeatus	88.76	0.00e+00	793.00
IUUC-Ggo-044619	Gorilla gorilla	73.94	0.00e+00	669.00
IUUC-Hsa-046300	Homo sapiens	73.47	0.00e+00	665.00
IUUC-Itr-048830	Ictidomys tridecemlineatus	73.94	0.00e+00	667.00
IUUC-Lch-049550	Latimeria chalumnae	75.00	2.00e-158	551.00
IUUC-Loc-051769	Lepisosteus oculatus	79.76	0.00e+00	705.00
IUUC-Laf-054576	Loxodonta africana	74.41	0.00e+00	654.00
IUUC-Mcc-054666	Macaca mulatta	74.81	5.00e-121	426.00
IUUC-Meu-055989	Macropus eugenii	73.56	1.00e-154	538.00
IUUC-Mga-059722	Meleagris gallopavo	73.06	0.00e+00	644.00
IUUC-Mmr-060970	Microcebus murinus	73.00	0.00e+00	645.00
IUUC-Mdo-062249	Monodelphis domestica	63.38	5.00e-150	523.00
IUUC-Mmu-063742	Mus musculus	71.06	0.00e+00	643.00
IUUC-Mpu-066518	Mustela putorius furo	73.24	0.00e+00	664.00
IUUC-Mlu-068063	Myotis lucifugus	72.07	0.00e+00	633.00
IUUC-Nle-069561	Nomascus leucogenys	73.94	0.00e+00	669.00
IUUC-Opr-071158	Ochotona princeps	70.35	0.00e+00	632.00
IUUC-Ont-072542	Oreochromis niloticus	90.87	0.00e+00	806.00
IUUC-Oan-073217	Ornithorhynchus anatinus	73.88	0.00e+00	664.00
IUUC-Ocu-074251	Oryctolagus cuniculus	72.71	0.00e+00	634.00
IUUC-Ola-086549	Oryzias latipes	86.65	0.00e+00	780.00
IUUC-Oga-088382	Otolemur garnettii	73.00	0.00e+00	647.00
IUUC-Oar-090263	Ovis aries	72.30	0.00e+00	649.00
IUUC-Ptr-090922	Pan troglodytes	73.71	0.00e+00	667.00
IUUC-Pan-092518	Papio anubis	73.47	0.00e+00	666.00
IUUC-Psi-093512	Pelodiscus sinensis	73.24	0.00e+00	656.00
IUUC-Pma-094324	Petromyzon marinus	57.41	7.00e-138	483.00
IUUC-Pfo-096264	Poecilia formosa	98.13	0.00e+00	873.00
IUUC-Pab-098018	Pongo abelii	72.30	0.00e+00	654.00
IUUC-Pca-101034	Procavia capensis	73.54	6.00e-176	609.00
IUUC-Pva-102862	Pteropus vampyrus	70.42	1.00e-170	592.00
IUUC-Rno-106116	Rattus norvegicus	72.07	0.00e+00	654.00
IUUC-Sha-106952	Sarcophilus harrisii	71.50	2.00e-179	622.00
IUUC-Sar-113211	Sorex araneus	67.80	9.00e-121	426.00
IUUC-Ssc-116440	Sus scrofa	73.00	0.00e+00	647.00
IUUC-Tgu-116675	Taeniopygia guttata	71.12	3.00e-179	620.00
IUUC-Tru-118295	Takifugu rubripes	84.78	0.00e+00	760.00
IUUC-Tsy-118916	Tarsius syrichta	62.91	5.00e-154	537.00
IUUC-Tni-120302	Tetraodon nigroviridis	84.54	0.00e+00	754.00
IUUC-Tbe-127416	Tupaia belangeri	63.35	5.00e-150	523.00
IUUC-Ttr-128185	Tursiops truncatus	73.47	0.00e+00	649.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence