iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048050

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01073023

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000009022.2	ENSSTOT00000009029.2	ENSSTOP00000008091.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.30e-86	291.1	381	680

Active Site

Position(s)	Description	Evidence
648	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 41   lglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgk..............klsledleevdp 115
            g+f+y+++++++++ + +      ++ + F+++G+l+g+a++++  ld+++++++yk+ll+               ++ ++dl +++p
   Q: 381  SGMFTYHKDSHCHWFSSFKC-----DNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPpivpsdqntpvgicSVAIDDLCQIMP 464
           49************977766.....789**********************************9666666666555555999******** PP
   S: 116  elykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviple 204
           el++ l+e++++ e ++ee  +  tf+v +e++g +k+++LkpgG++ipVtn+N++eYv+l++++ ++++i +q++af+ Gf++v+  +
   Q: 465  ELAHGLTELLSY-EGNVEED-FYSTFQVFQEEFGIIKSYNLKPGGDKIPVTNQNRKEYVQLYTDFLINKSIYKQFAAFYYGFHSVCASN 551
           ***********9.6788885.******************************************************************** PP
   S: 205  llslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.d 292
            l l+++ee+e+l+cG++e+d+++l++ t+y+g y +++ +i++Fw+v+ +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k +
   Q: 552  ALMLLRPEEVEILVCGSPELDMHALQRSTQYDG-YAKTDLTIRYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnE 636
           *******************************76.*********************************************...9999967 PP
   S: 293  asddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +s+++lP ++TCfn+L+LP+Y+sk+ lk+kL++ i++++gF+l+
   Q: 637  TSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 680
           777**************************************985 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

RDLPPICLDV RQKQRIPIDT LPSEMKAPVL TEPILPIQPK TMKDFQEDVE KAKPSGDWKT 60
VHDFYLTTFD SFPGLNAIFK KDATASFNTI EDSGINAKFV NAVYDALLNT PQDIQKTVLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGTTAGGTT ATGTGGCTCC TTTGTACTTC AGATAATTTG GTTCTAGCAA AGTAAGTCAG 60
TTTCATCTAT CTGTTATCAA ATTTAAATAT TGTAAACGTT ATTTTATTTC TGCAATAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	90.03	0.00e+00	1251.00
IUUC-Apl-003589	Anas platyrhynchos	81.71	0.00e+00	1141.00
IUUC-Aca-004350	Anolis carolinensis	77.33	0.00e+00	1069.00
IUUC-Ate-010295	Aspergillus terreus	33.67	2.00e-80	294.00
IUUC-Ame-010660	Astyanax mexicanus	81.46	3.00e-153	533.00
IUUC-Bta-012945	Bos taurus	90.26	0.00e+00	1221.00
IUUC-Cja-019263	Callithrix jacchus	88.44	0.00e+00	1199.00
IUUC-Cfa-020486	Canis familiaris	90.73	0.00e+00	1182.00
IUUC-Cpo-021755	Cavia porcellus	89.77	0.00e+00	1246.00
IUUC-Csa-023814	Chlorocebus sabaeus	89.06	0.00e+00	1137.00
IUUC-Cho-024980	Choloepus hoffmanni	70.49	0.00e+00	916.00
IUUC-Dre-028551	Danio rerio	74.27	0.00e+00	1020.00
IUUC-Dno-029497	Dasypus novemcinctus	87.26	0.00e+00	1157.00
IUUC-Dor-030867	Dipodomys ordii	77.62	0.00e+00	1029.00
IUUC-Ete-032902	Echinops telfairi	76.89	0.00e+00	1030.00
IUUC-Eca-033678	Equus caballus	90.26	0.00e+00	1229.00
IUUC-Eeu-035262	Erinaceus europaeus	72.38	0.00e+00	946.00
IUUC-Fca-035590	Felis catus	90.41	0.00e+00	1253.00
IUUC-Fal-037123	Ficedula albicollis	77.95	0.00e+00	1071.00
IUUC-Gmo-039553	Gadus morhua	61.18	0.00e+00	776.00
IUUC-Gga-040406	Gallus gallus	81.98	0.00e+00	1150.00
IUUC-Gac-042141	Gasterosteus aculeatus	71.24	0.00e+00	1010.00
IUUC-Ggo-045504	Gorilla gorilla	88.01	0.00e+00	1199.00
IUUC-Hsa-045786	Homo sapiens	88.81	0.00e+00	1206.00
IUUC-Lch-049824	Latimeria chalumnae	76.62	0.00e+00	972.00
IUUC-Loc-052173	Lepisosteus oculatus	76.74	0.00e+00	1060.00
IUUC-Laf-054017	Loxodonta africana	89.97	0.00e+00	1226.00
IUUC-Mcc-055713	Macaca mulatta	89.16	0.00e+00	1211.00
IUUC-Meu-056212	Macropus eugenii	72.48	2.00e-111	396.00
IUUC-Mla-059187	Melampsora laricipopulina	37.97	3.00e-71	262.00
IUUC-Mga-059884	Meleagris gallopavo	75.04	0.00e+00	1001.00
IUUC-Mmr-061344	Microcebus murinus	89.53	0.00e+00	1240.00
IUUC-Mdo-062653	Monodelphis domestica	84.56	0.00e+00	1160.00
IUUC-Mmu-063775	Mus musculus	86.77	0.00e+00	1135.00
IUUC-Mpu-066069	Mustela putorius furo	90.36	0.00e+00	1206.00
IUUC-Mlu-067925	Myotis lucifugus	89.53	0.00e+00	1214.00
IUUC-Nle-070046	Nomascus leucogenys	88.44	0.00e+00	1229.00
IUUC-Opr-071085	Ochotona princeps	79.87	9.00e-138	484.00
IUUC-Ont-072126	Oreochromis niloticus	72.24	0.00e+00	1035.00
IUUC-Oan-072933	Ornithorhynchus anatinus	82.59	0.00e+00	1066.00
IUUC-Ocu-073800	Oryctolagus cuniculus	90.66	0.00e+00	1185.00
IUUC-Ola-086988	Oryzias latipes	71.26	0.00e+00	1021.00
IUUC-Oga-088117	Otolemur garnettii	90.21	0.00e+00	1023.00
IUUC-Oar-089371	Ovis aries	90.26	0.00e+00	1202.00
IUUC-Ptr-090551	Pan troglodytes	88.29	0.00e+00	1202.00
IUUC-Pan-092067	Papio anubis	89.68	0.00e+00	1217.00
IUUC-Psi-092963	Pelodiscus sinensis	82.70	0.00e+00	1113.00
IUUC-Pfo-096562	Poecilia formosa	70.35	0.00e+00	1016.00
IUUC-Pab-098680	Pongo abelii	89.10	0.00e+00	1209.00
IUUC-Pca-100986	Procavia capensis	76.37	0.00e+00	885.00
IUUC-Pva-102219	Pteropus vampyrus	78.41	0.00e+00	912.00
IUUC-Pgr-103315	Puccinia graminis	33.38	7.00e-74	271.00
IUUC-Rno-105270	Rattus norvegicus	87.06	0.00e+00	1134.00
IUUC-Sha-106819	Sarcophilus harrisii	86.34	0.00e+00	1205.00
IUUC-Sar-113134	Sorex araneus	78.74	0.00e+00	1037.00
IUUC-Ssc-115441	Sus scrofa	90.26	0.00e+00	1220.00
IUUC-Tgu-117166	Taeniopygia guttata	80.12	0.00e+00	1093.00
IUUC-Tsy-118898	Tarsius syrichta	77.27	0.00e+00	958.00
IUUC-Tme-127004	Tuber melanosporum	32.42	1.00e-82	301.00
IUUC-Tbe-127292	Tupaia belangeri	72.24	0.00e+00	914.00
IUUC-Ttr-128352	Tursiops truncatus	85.90	0.00e+00	1151.00
IUUC-Vpa-130218	Vicugna pacos	84.91	0.00e+00	815.00
IUUC-Xtr-132594	Xenopus tropicalis	74.89	0.00e+00	989.00
IUUC-Xma-134157	Xiphophorus maculatus	69.80	0.00e+00	945.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence