iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091087

Ensembl Protein ID

ENSPTRP00000032937.3

UniProt Accession

H2QUP7; H2QUP7_PANTR

Genbank Protein ID

JAA10810.1; JAA13084.1; JAA28808.1; JAA36136.1

Protein Name

Transducin (Beta)-like 2

Genbank Nucleotide ID

AC198629; GABF01009061; GABD01004292; GABE01008603

Gene Name

TBL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000019273.5	ENSPTRT00000035631.3	ENSPTRP00000032937.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-20	71.9	89	122
UBD/Beta-Prp	5.50e-52	176.8	75	309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H++ ++c++f s+ ++l++++dD ti++W+++++
   Q: 89   HSGNISCMDFsSNgKYLATCADDRTIRIWSTKDF 122
           9**********777***************98775 PP

UBD/Beta-Prp

   S: 37   wdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls....tgkcvhtlkghedsvlslsfspsg.dklvsGshdrtirv 120
           +++t   l + l++h++ +++++fs++gk+l+t+++Drti++w+ +         +  + + d +++++fsp+   ++v   + +t+rv
   Q: 75   HNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTIRIWSTKdflqREHRSMRANVELDHATLVRFSPDCrAFIVWLANGDTLRV 163
           566777778999*******************************7773433333333344678999*******655************** PP
   S: 121  wdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsld 201
           +++ +++            + ++h++ v  + +  +g+ ++++s D+tv +W+l  g++l t    ++   ++ ++++ g++++s++  
   Q: 164  FKMTKREDGGYtftatpedFPKKHKAPVIDIGIANTGKFIMTASSDTTVLIWSL-KGQVLSTINT-NQMNNTHAAVSPCGRFVASCGFT 250
           *999887665567789999*********************************99.7888888887.899999999************** PP
   S: 202  gtvklwdlqtgec........vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
            +vk+w++  g+           +l+gh++ v s +fs+++ r++s+s+Dg+ ++Wd++
   Q: 251  PDVKVWEVCFGKKgefqevvrAFELKGHSAAVHSFAFSNDSRRMASVSKDGTWKLWDTD 309
           ********944444447777788999******************************865 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MELSQMSELM GLSVLLGLLA LMATAAVARG WLRAGEERSG RPACQKANGF PPDKSSGSKK 60
QKQYQRIRKE KPQQHNFTHR LLAAALKSHS GNISCMDFSS NGKYLATCAD DRTIRIWSTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCTCTAAC GGCCCGGCCC AGCCGCTTGA GGCGCCCCAA CGGCCAGGCC GCGCCTCTGC 60
GTGCGTGCGT GCGCGGCCCG GCAGAGTCGT GCGGGCGCCC GCGTACTCAC TAGCTGAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005783--C:endoplasmic reticulum
GO:0003723--F:RNA binding
GO:0042149--P:cellular response to glucose starvation
GO:0071456--P:cellular response to hypoxia
GO:0030968--P:endoplasmic reticulum unfolded protein response

KEGG

ptr:463462

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000109	Aegilops tauschii	32.16	5.00e-23	100.00
IUUC-Aml-002212	Ailuropoda melanoleuca	91.29	0.00e+00	733.00
IUUC-Atr-002903	Amborella trichopoda	29.18	2.00e-36	146.00
IUUC-Apl-003635	Anas platyrhynchos	72.55	5.00e-161	560.00
IUUC-Aca-004472	Anolis carolinensis	72.63	3.00e-166	577.00
IUUC-Aly-005761	Arabidopsis lyrata	30.83	6.00e-39	154.00
IUUC-Ath-007476	Arabidopsis thaliana	31.50	1.00e-39	157.00
IUUC-Ame-011221	Astyanax mexicanus	67.53	2.00e-148	518.00
IUUC-Bta-013186	Bos taurus	88.81	0.00e+00	736.00
IUUC-Bdi-014298	Brachypodium distachyon	29.68	4.00e-38	152.00
IUUC-Bol-015192	Brassica oleracea	30.23	9.00e-38	150.00
IUUC-Bra-017078	Brassica rapa	30.79	7.00e-39	154.00
IUUC-Cel-018602	Caenorhabditis elegans	30.51	6.00e-59	221.00
IUUC-Cja-018909	Callithrix jacchus	93.51	0.00e+00	768.00
IUUC-Cfa-020970	Canis familiaris	90.16	0.00e+00	754.00
IUUC-Cpo-022215	Cavia porcellus	85.44	0.00e+00	687.00
IUUC-Cre-022949	Chlamydomonas reinhardtii	33.80	2.00e-20	91.30
IUUC-Csa-023530	Chlorocebus sabaeus	95.97	0.00e+00	804.00
IUUC-Cho-024598	Choloepus hoffmanni	92.34	5.00e-140	490.00
IUUC-Cin-025486	Ciona intestinalis	49.74	4.00e-105	374.00
IUUC-Csv-025930	Ciona savignyi	46.63	5.00e-95	341.00
IUUC-Dre-027507	Danio rerio	66.85	6.00e-150	523.00
IUUC-Dno-029726	Dasypus novemcinctus	89.50	0.00e+00	745.00
IUUC-Dor-030501	Dipodomys ordii	76.73	4.00e-173	600.00
IUUC-Ete-032794	Echinops telfairi	85.09	2.00e-130	457.00
IUUC-Eca-033982	Equus caballus	89.49	0.00e+00	704.00
IUUC-Eeu-035090	Erinaceus europaeus	87.78	4.00e-134	471.00
IUUC-Fca-035944	Felis catus	91.04	0.00e+00	771.00
IUUC-Fal-036992	Ficedula albicollis	65.97	1.00e-148	519.00
IUUC-Gmo-038710	Gadus morhua	62.63	9.00e-146	509.00
IUUC-Gga-040885	Gallus gallus	68.79	1.00e-111	395.00
IUUC-Gac-041922	Gasterosteus aculeatus	64.80	4.00e-152	530.00
IUUC-Gma-044233	Glycine max	29.61	1.00e-37	150.00
IUUC-Ggo-045172	Gorilla gorilla	99.26	0.00e+00	785.00
IUUC-Hsa-045711	Homo sapiens	99.78	0.00e+00	833.00
IUUC-Itr-048196	Ictidomys tridecemlineatus	89.71	0.00e+00	730.00
IUUC-Lch-049739	Latimeria chalumnae	70.78	2.00e-164	572.00
IUUC-Lpe-050795	Leersia perrieri	25.65	2.00e-21	96.30
IUUC-Loc-052113	Lepisosteus oculatus	72.21	2.00e-153	535.00
IUUC-Laf-053751	Loxodonta africana	87.70	0.00e+00	750.00
IUUC-Mcc-055022	Macaca mulatta	96.36	0.00e+00	795.00
IUUC-Meu-056003	Macropus eugenii	73.24	6.00e-162	563.00
IUUC-Mtr-058500	Medicago truncatula	29.55	9.00e-35	140.00
IUUC-Mga-059278	Meleagris gallopavo	68.14	3.00e-123	434.00
IUUC-Mmr-061148	Microcebus murinus	91.05	0.00e+00	753.00
IUUC-Mdo-063002	Monodelphis domestica	71.89	2.00e-160	558.00
IUUC-Mmu-063607	Mus musculus	87.02	0.00e+00	708.00
IUUC-Mac-065359	Musa acuminata	27.96	7.00e-36	144.00
IUUC-Mpu-066323	Mustela putorius furo	91.82	2.00e-177	614.00
IUUC-Mlu-067946	Myotis lucifugus	90.83	0.00e+00	761.00
IUUC-Nle-069019	Nomascus leucogenys	98.43	0.00e+00	818.00
IUUC-Opr-071047	Ochotona princeps	88.37	0.00e+00	726.00
IUUC-Ont-071694	Oreochromis niloticus	66.22	3.00e-151	528.00
IUUC-Oan-073474	Ornithorhynchus anatinus	56.23	7.00e-100	357.00
IUUC-Ocu-074493	Oryctolagus cuniculus	88.81	0.00e+00	708.00
IUUC-Oba-075468	Oryza barthii	26.38	5.00e-32	132.00
IUUC-Obr-076681	Oryza brachyantha	26.55	2.00e-33	136.00
IUUC-Ogl-077870	Oryza glaberrima	26.38	5.00e-32	132.00
IUUC-Ogu-078536	Oryza glumaepatula	26.38	6.00e-32	131.00
IUUC-Oin-080175	Oryza indica	26.38	5.00e-32	132.00
IUUC-Olo-080796	Oryza longistaminata	26.61	6.00e-31	128.00
IUUC-Oni-082076	Oryza nivara	26.38	5.00e-32	132.00
IUUC-Opu-083267	Oryza punctata	26.74	2.00e-32	133.00
IUUC-Oru-084553	Oryza rufipogon	26.67	1.00e-32	134.00
IUUC-Osa-085389	Oryza sativa	26.38	5.00e-32	132.00
IUUC-Ola-086414	Oryzias latipes	65.95	2.00e-149	521.00
IUUC-Oga-088656	Otolemur garnettii	88.37	0.00e+00	749.00
IUUC-Oar-089719	Ovis aries	89.08	0.00e+00	696.00
IUUC-Pan-091709	Papio anubis	96.64	0.00e+00	809.00
IUUC-Psi-093265	Pelodiscus sinensis	70.97	6.00e-170	589.00
IUUC-Pma-094482	Petromyzon marinus	56.74	3.00e-57	213.00
IUUC-Ppa-095365	Physcomitrella patens	29.04	6.00e-40	158.00
IUUC-Pfo-097494	Poecilia formosa	66.76	2.00e-149	521.00
IUUC-Pab-098362	Pongo abelii	98.88	0.00e+00	827.00
IUUC-Pop-099163	Populus trichocarpa	29.14	2.00e-32	133.00
IUUC-Pca-101019	Procavia capensis	85.91	3.00e-152	531.00
IUUC-Ppe-102101	Prunus persica	28.76	5.00e-39	155.00
IUUC-Pva-102849	Pteropus vampyrus	90.74	0.00e+00	724.00
IUUC-Rno-105511	Rattus norvegicus	87.70	0.00e+00	705.00
IUUC-Sha-107265	Sarcophilus harrisii	68.66	6.00e-166	577.00
IUUC-Smo-108980	Selaginella moellendorffii	32.09	8.00e-37	147.00
IUUC-Sit-110806	Setaria italica	27.09	8.00e-34	137.00
IUUC-Sly-110994	Solanum lycopersicum	28.57	1.00e-34	140.00
IUUC-Stu-112493	Solanum tuberosum	35.42	2.00e-31	129.00
IUUC-Sar-113628	Sorex araneus	85.04	0.00e+00	686.00
IUUC-Sbi-114397	Sorghum bicolor	28.12	3.00e-34	139.00
IUUC-Ssc-116418	Sus scrofa	89.04	0.00e+00	756.00
IUUC-Tgu-117054	Taeniopygia guttata	66.84	1.00e-154	539.00
IUUC-Tru-118504	Takifugu rubripes	66.84	2.00e-158	551.00
IUUC-Tni-120254	Tetraodon nigroviridis	66.33	9.00e-156	543.00
IUUC-Tca-121085	Theobroma cacao	30.36	2.00e-37	149.00
IUUC-Tae-124320	Triticum aestivum	28.74	2.00e-37	149.00
IUUC-Tur-126756	Triticum urartu	26.83	1.00e-31	130.00
IUUC-Tbe-127903	Tupaia belangeri	86.80	0.00e+00	729.00
IUUC-Ttr-129118	Tursiops truncatus	88.07	0.00e+00	747.00
IUUC-Vvi-131125	Vitis vinifera	30.45	4.00e-37	148.00
IUUC-Xtr-132287	Xenopus tropicalis	72.55	3.00e-162	564.00
IUUC-Xma-134246	Xiphophorus maculatus	66.19	2.00e-149	521.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence