iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105207

Ensembl Protein ID

ENSRNOP00000016784.6

UniProt Accession

A0A1P0PBZ6; A0A1P0PBZ6_RAT

Genbank Protein ID

ENSRNOP00000016784

Protein Name

Triple functional domain protein

Genbank Nucleotide ID

AABR07008947

Gene Name

Trio

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000012148.7	ENSRNOT00000016784.7	ENSRNOP00000016784.6

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.80e-13	48.6	1610	1661

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk..elegkrGlfP 55
             v++d++a n++eLt+++G +v+v+e  +   +W+           +Gl+P
   Q: 1610 TVVIHDFTACNSNELTIRRGQTVEVLERPHDKPDWCLVRTtdRSPAAEGLVP 1661
           679********************************97755334445678887 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

SGFRKNDEMK AMDVLPILKE KVAYLSGGRD KRGGPILTFP ARSNHDRMRQ EDLRRLISYL 60
ACIPSEEVCK RGFTVIVDMR GSKWDSIKPL LKILQESFPC CIHIALIIKP DNFWQKQRTN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGGGTTTC GAAAAAATGA TGAAATGAAA GCTATGGATG TTTTGCCCAT CCTGAAGGAA 60
AAAGTCGCCT ACCTTTCAGG TAAAATCTGA CTTTCTAACC CGCTGTACTT GACTGCTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR001251--CRAL-TRIO_dom
IPR000219--DH-domain
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR013098--Ig_I-set
IPR003599--Ig_sub
IPR003598--Ig_sub2
IPR011009--Kinase-like_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain
IPR018159--Spectrin/alpha-actinin
IPR002017--Spectrin_repeat
IPR028570--TRIO

PROSITE

PS50191--CRAL_TRIO
PS50010--DH_2
PS50835--IG_LIKE
PS50003--PH_DOMAIN
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF00650--CRAL_TRIO
PF07679--I-set
PF00169--PH
PF00069--Pkinase
PF00621--RhoGEF
PF00018--SH3_1
PF00435--Spectrin

SMART

SM00409--IG
SM00408--IGc2
SM00233--PH
SM00325--RhoGEF
SM00220--S_TKc
SM00516--SEC14
SM00326--SH3
SM00150--SPEC

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001797	Ailuropoda melanoleuca	93.66	0.00e+00	5532.00
IUUC-Apl-003498	Anas platyrhynchos	93.15	0.00e+00	5162.00
IUUC-Bta-013121	Bos taurus	93.65	0.00e+00	5501.00
IUUC-Cja-018919	Callithrix jacchus	95.48	0.00e+00	5513.00
IUUC-Cfa-020547	Canis familiaris	94.04	0.00e+00	5490.00
IUUC-Cpo-022301	Cavia porcellus	97.38	0.00e+00	5685.00
IUUC-Csa-023889	Chlorocebus sabaeus	98.93	0.00e+00	4376.00
IUUC-Dre-028386	Danio rerio	89.12	0.00e+00	3905.00
IUUC-Dno-028888	Dasypus novemcinctus	93.52	0.00e+00	5491.00
IUUC-Dor-030992	Dipodomys ordii	90.04	0.00e+00	4574.00
IUUC-Ete-033167	Echinops telfairi	86.03	0.00e+00	2070.00
IUUC-Eca-033685	Equus caballus	98.30	0.00e+00	4331.00
IUUC-Fca-035647	Felis catus	97.68	0.00e+00	4350.00
IUUC-Fal-036845	Ficedula albicollis	93.50	0.00e+00	5517.00
IUUC-Gga-040959	Gallus gallus	93.17	0.00e+00	5556.00
IUUC-Gac-041349	Gasterosteus aculeatus	87.45	0.00e+00	3769.00
IUUC-Ggo-045170	Gorilla gorilla	98.92	0.00e+00	4355.00
IUUC-Hsa-046059	Homo sapiens	94.79	0.00e+00	5533.00
IUUC-Lch-050010	Latimeria chalumnae	92.82	0.00e+00	4059.00
IUUC-Loc-052783	Lepisosteus oculatus	85.81	0.00e+00	5049.00
IUUC-Laf-053884	Loxodonta africana	98.52	0.00e+00	4342.00
IUUC-Mcc-055804	Macaca mulatta	98.53	0.00e+00	4360.00
IUUC-Mga-060008	Meleagris gallopavo	82.64	0.00e+00	1206.00
IUUC-Mmr-061081	Microcebus murinus	95.74	0.00e+00	5613.00
IUUC-Mdo-062888	Monodelphis domestica	98.79	0.00e+00	3997.00
IUUC-Mmu-063327	Mus musculus	99.38	0.00e+00	5737.00
IUUC-Mpu-066905	Mustela putorius furo	98.66	0.00e+00	4369.00
IUUC-Mlu-068215	Myotis lucifugus	95.72	0.00e+00	4282.00
IUUC-Nle-069414	Nomascus leucogenys	96.56	0.00e+00	4236.00
IUUC-Opr-070819	Ochotona princeps	95.17	0.00e+00	4187.00
IUUC-Ont-072678	Oreochromis niloticus	89.10	0.00e+00	3876.00
IUUC-Oan-072974	Ornithorhynchus anatinus	98.30	0.00e+00	4354.00
IUUC-Ocu-074919	Oryctolagus cuniculus	94.89	0.00e+00	5526.00
IUUC-Oga-088068	Otolemur garnettii	96.10	0.00e+00	5663.00
IUUC-Oar-090050	Ovis aries	95.28	0.00e+00	4227.00
IUUC-Ptr-090841	Pan troglodytes	98.93	0.00e+00	4382.00
IUUC-Psi-093088	Pelodiscus sinensis	97.54	0.00e+00	4289.00
IUUC-Pfo-097201	Poecilia formosa	77.56	0.00e+00	3394.00
IUUC-Pab-098130	Pongo abelii	98.79	0.00e+00	4367.00
IUUC-Pca-100839	Procavia capensis	94.53	0.00e+00	2574.00
IUUC-Pva-102115	Pteropus vampyrus	94.68	0.00e+00	2873.00
IUUC-Sha-107011	Sarcophilus harrisii	89.25	0.00e+00	4227.00
IUUC-Tgu-116970	Taeniopygia guttata	92.45	0.00e+00	5448.00
IUUC-Tru-117758	Takifugu rubripes	87.64	0.00e+00	3837.00
IUUC-Ttr-128857	Tursiops truncatus	90.12	0.00e+00	3958.00
IUUC-Xtr-131909	Xenopus tropicalis	86.70	0.00e+00	5160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence