iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117049

Ensembl Protein ID

ENSTGUP00000005724.1

UniProt Accession

H0Z578; H0Z578_TAEGU

Genbank Protein ID

ENSTGUP00000005724

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01001459

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000005520.1	ENSTGUT00000005782.1	ENSTGUP00000005724.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.10e-13	48.6	457	506

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 457  IALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--VCKGRYGLFPANYVE 506
           79***********************..9*********..7************97 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MWKATAGHTV SVSQDYGADD WETDPDFVND VSEKEQRWGA KTVNGSGHQE HINIHQLREN 60
VFQEHQNLKE RELQTGPKAS HGYGGKFGVE QDRMDKSAVG HEYQSKLSKH CSQVDLVKGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGAAGG CTACTGCAGG CCACACCGTG TCTGTCAGCC AGGATTATGG AGCTGATGAC 60
TGGGAGACAG ATCCAGACTT TGTGGTATGG CTTTTGGGGT TTACTGATCC ACCAGGAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	74.91	0.00e+00	754.00
IUUC-Apl-003745	Anas platyrhynchos	85.14	0.00e+00	764.00
IUUC-Aca-004438	Anolis carolinensis	76.07	0.00e+00	798.00
IUUC-Ame-011504	Astyanax mexicanus	62.65	9.00e-103	367.00
IUUC-Bgr-012041	Blumeria graminis	57.89	6.00e-16	79.00
IUUC-Bta-013563	Bos taurus	75.14	0.00e+00	725.00
IUUC-Bci-013690	Botrytis cinerea	58.82	4.00e-12	66.60
IUUC-Cfa-020718	Canis familiaris	72.63	0.00e+00	754.00
IUUC-Cpo-022303	Cavia porcellus	74.91	0.00e+00	820.00
IUUC-Csa-023431	Chlorocebus sabaeus	76.55	0.00e+00	760.00
IUUC-Cin-025677	Ciona intestinalis	55.10	8.00e-100	357.00
IUUC-Csv-026140	Ciona savignyi	64.53	6.00e-94	337.00
IUUC-Dre-028012	Danio rerio	68.96	0.00e+00	645.00
IUUC-Dno-029332	Dasypus novemcinctus	80.81	0.00e+00	729.00
IUUC-Dme-031931	Drosophila melanogaster	47.44	3.00e-81	295.00
IUUC-Eca-033801	Equus caballus	76.60	0.00e+00	755.00
IUUC-Fca-035633	Felis catus	73.48	3.00e-173	600.00
IUUC-Fal-036775	Ficedula albicollis	86.98	0.00e+00	811.00
IUUC-Fox-037778	Fusarium oxysporum	59.65	1.00e-14	75.10
IUUC-Gmo-038507	Gadus morhua	71.43	4.00e-20	92.40
IUUC-Gga-040568	Gallus gallus	83.73	0.00e+00	778.00
IUUC-Gac-042253	Gasterosteus aculeatus	57.31	4.00e-115	407.00
IUUC-Hsa-046818	Homo sapiens	76.73	0.00e+00	762.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	75.36	0.00e+00	726.00
IUUC-Lch-050199	Latimeria chalumnae	62.67	7.00e-121	427.00
IUUC-Loc-052855	Lepisosteus oculatus	84.33	2.00e-160	558.00
IUUC-Laf-053866	Loxodonta africana	76.31	0.00e+00	803.00
IUUC-Mcc-055515	Macaca mulatta	76.36	0.00e+00	741.00
IUUC-Mga-059791	Meleagris gallopavo	79.20	0.00e+00	771.00
IUUC-Mmr-061147	Microcebus murinus	76.27	0.00e+00	710.00
IUUC-Mdo-062660	Monodelphis domestica	63.36	6.00e-172	598.00
IUUC-Mmu-064023	Mus musculus	76.05	0.00e+00	746.00
IUUC-Mpu-065867	Mustela putorius furo	79.57	0.00e+00	741.00
IUUC-Mlu-067704	Myotis lucifugus	75.77	0.00e+00	707.00
IUUC-Ont-071873	Oreochromis niloticus	73.88	2.00e-147	515.00
IUUC-Oan-073528	Ornithorhynchus anatinus	74.81	4.00e-143	500.00
IUUC-Oga-088028	Otolemur garnettii	75.45	0.00e+00	746.00
IUUC-Oar-090203	Ovis aries	75.00	0.00e+00	666.00
IUUC-Pan-092594	Papio anubis	76.95	0.00e+00	744.00
IUUC-Psi-093389	Pelodiscus sinensis	79.26	0.00e+00	750.00
IUUC-Pma-094161	Petromyzon marinus	47.79	3.00e-87	315.00
IUUC-Pfo-097391	Poecilia formosa	62.31	2.00e-119	422.00
IUUC-Pab-097913	Pongo abelii	82.07	0.00e+00	753.00
IUUC-Rno-105489	Rattus norvegicus	74.95	0.00e+00	706.00
IUUC-Sce-106228	Saccharomyces cerevisiae	50.00	6.00e-07	48.90
IUUC-Sha-107308	Sarcophilus harrisii	74.37	0.00e+00	690.00
IUUC-Tru-118718	Takifugu rubripes	71.71	3.00e-148	518.00
IUUC-Tni-120535	Tetraodon nigroviridis	58.24	2.00e-167	582.00
IUUC-Vda-129766	Verticillium dahliae	57.89	1.00e-13	71.60
IUUC-Xtr-131797	Xenopus tropicalis	61.94	1.00e-169	589.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence