iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091822

Ensembl Protein ID

ENSPANP00000019325.1

UniProt Accession

A0A096P1V0; A0A096P1V0_PAPAN

Genbank Protein ID

ENSPANP00000019325

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01007995

Gene Name

TLE1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000024905.1	ENSPANT00000025187.1	ENSPANP00000019325.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-21	75.6	648	686

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 648  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 686
           8***********999*********************998 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MFPQSRHPTP HQAAGQPFKF TIPESLDRIK EEFQFLQAQY HSLKLECEKL ASEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNTICA QVIPFLSQEH QQQVAQAVER AKQVTMAELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCCCGC AGAGCCGGCA CCCGGTGAGG CGCGGCTGGG TGGTGGGGGA GCAGGAGCGT 60
TGGGGAGGCG CTTCTCCCGG GCGGTAGGGA GACGGGTGGC TTCTGCGGCC CGGCGGACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0001106--F:RNA polymerase II transcription corepressor activity
GO:2000811--P:negative regulation of anoikis
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0010628--P:positive regulation of gene expression

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003594	Anas platyrhynchos	90.72	0.00e+00	1234.00
IUUC-Aca-005053	Anolis carolinensis	90.17	0.00e+00	1274.00
IUUC-Bta-013380	Bos taurus	87.08	0.00e+00	1146.00
IUUC-Cja-019135	Callithrix jacchus	95.52	0.00e+00	1303.00
IUUC-Cfa-020611	Canis familiaris	94.92	0.00e+00	1182.00
IUUC-Cpo-022495	Cavia porcellus	94.53	0.00e+00	1294.00
IUUC-Csa-024056	Chlorocebus sabaeus	95.65	0.00e+00	1325.00
IUUC-Dno-029011	Dasypus novemcinctus	94.66	0.00e+00	1294.00
IUUC-Ete-032533	Echinops telfairi	83.21	0.00e+00	1177.00
IUUC-Eca-033351	Equus caballus	95.52	0.00e+00	1303.00
IUUC-Eeu-034666	Erinaceus europaeus	93.94	0.00e+00	1067.00
IUUC-Fal-036696	Ficedula albicollis	93.32	0.00e+00	1245.00
IUUC-Gga-041113	Gallus gallus	93.91	0.00e+00	1345.00
IUUC-Gac-041999	Gasterosteus aculeatus	77.64	0.00e+00	1169.00
IUUC-Ggo-045164	Gorilla gorilla	95.77	0.00e+00	1326.00
IUUC-Hsa-047011	Homo sapiens	95.77	0.00e+00	1326.00
IUUC-Lch-050437	Latimeria chalumnae	90.13	0.00e+00	1110.00
IUUC-Loc-052819	Lepisosteus oculatus	87.48	0.00e+00	1223.00
IUUC-Laf-053862	Loxodonta africana	92.14	0.00e+00	1262.00
IUUC-Mcc-055735	Macaca mulatta	100.00	0.00e+00	1415.00
IUUC-Mmr-061207	Microcebus murinus	92.01	0.00e+00	1256.00
IUUC-Mdo-062493	Monodelphis domestica	94.65	0.00e+00	1350.00
IUUC-Mmu-063795	Mus musculus	89.71	0.00e+00	1256.00
IUUC-Mpu-065819	Mustela putorius furo	95.03	0.00e+00	1328.00
IUUC-Mlu-067047	Myotis lucifugus	95.15	0.00e+00	1286.00
IUUC-Nle-069684	Nomascus leucogenys	95.52	0.00e+00	1318.00
IUUC-Opr-071172	Ochotona princeps	94.15	0.00e+00	1276.00
IUUC-Ont-072102	Oreochromis niloticus	78.31	0.00e+00	1181.00
IUUC-Ocu-074592	Oryctolagus cuniculus	92.04	0.00e+00	1306.00
IUUC-Oga-088629	Otolemur garnettii	92.51	0.00e+00	1260.00
IUUC-Oar-089551	Ovis aries	94.16	0.00e+00	1280.00
IUUC-Ptr-091207	Pan troglodytes	95.40	0.00e+00	1321.00
IUUC-Psi-093594	Pelodiscus sinensis	91.21	0.00e+00	1267.00
IUUC-Pfo-096239	Poecilia formosa	77.35	0.00e+00	1173.00
IUUC-Pab-097687	Pongo abelii	95.73	0.00e+00	1309.00
IUUC-Pca-100675	Procavia capensis	93.23	0.00e+00	1044.00
IUUC-Pva-102355	Pteropus vampyrus	91.28	0.00e+00	1191.00
IUUC-Rno-106027	Rattus norvegicus	92.68	0.00e+00	1312.00
IUUC-Sha-107419	Sarcophilus harrisii	89.94	0.00e+00	1267.00
IUUC-Sar-113585	Sorex araneus	86.75	0.00e+00	717.00
IUUC-Ssc-116151	Sus scrofa	95.02	0.00e+00	1296.00
IUUC-Tgu-117387	Taeniopygia guttata	93.28	0.00e+00	1321.00
IUUC-Tsy-119342	Tarsius syrichta	88.15	0.00e+00	1014.00
IUUC-Tbe-127881	Tupaia belangeri	92.41	0.00e+00	1283.00
IUUC-Xtr-131792	Xenopus tropicalis	85.66	0.00e+00	1231.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence