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Tag Content
iUUCD ID IUUC-Mga-059329
Ensembl Protein ID ENSMGAP00000003099.2
UniProt Accession G1MWG7; G1MWG7_MELGA
Protein Name Phosphoinositide phospholipase C
Gene Name PLCG1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMGAG00000003334.2 ENSMGAT00000003793.2 ENSMGAP00000003099.2
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.70e-12 46.9 724 782
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekle 63
           +k  v++l+dy+aq +deLt++k  +++ +  e+q++gW++g  +  gk+ l fP+n+ve+++
   Q: 724  FKCAVKALFDYKAQREDELTFTKNAIIQNV--EKQEGGWWRG--DYGGKKQLwFPSNYVEEIS 782
           56789************************9..9*********..676666655*******996 PP
   
Organism Meleagris gallopavo
Protein Sequence
(Fasta)
SVDIREIKEI RPGKNSRDFD RYQEDPCFRP DQSHCFVVLY GTEFRLKTLS LQATSEDEVN 60
MWIKGLNWLV ADTLRAATPL QIERWLRKQF YTLDRNREDR ISAKDLKNML SQVNYRVPNM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mga-059329|UBD,SH3|Meleagris gallopavo
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCAGTGGATA TTCGTGAAAT CAAAGAGATT CGTCCTGGAA AGAATTCACG TGATTTTGAC 60
CGATACCAGG AGGATCCGTG CTTCCGACCA GACCAGTCCC ATTGCTTCGT GGTCCTGTAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mga-059329|UBD,SH3|Meleagris gallopavo
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer
Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028380--PLC-gamma1
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3
Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
SMART

SM00239--C2
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005911--C:cell-cell junction
GO:0008180--C:COP9 signalosome
GO:0005829--C:cytosol
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0005509--F:calcium ion binding
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0019722--P:calcium-mediated signaling
GO:0016477--P:cell migration
GO:0071364--P:cellular response to epidermal growth factor stimulus
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0009395--P:phospholipid catabolic process
GO:0045766--P:positive regulation of angiogenesis
GO:0043536--P:positive regulation of blood vessel endothelial cell migration
GO:0051281--P:positive regulation of release of sequestered calcium ion into cytosol
GO:0050852--P:T cell receptor signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001452 Ailuropoda melanoleuca 88.73 0.00e+00 2229.00
IUUC-Aca-005291 Anolis carolinensis 88.57 0.00e+00 2199.00
IUUC-Afu-009104 Aspergillus fumigatus 37.50 2.00e-10 62.00
IUUC-Ame-011004 Astyanax mexicanus 68.40 0.00e+00 1682.00
IUUC-Bta-012660 Bos taurus 88.48 0.00e+00 2222.00
IUUC-Cja-019206 Callithrix jacchus 88.06 0.00e+00 2206.00
IUUC-Cfa-020257 Canis familiaris 88.64 0.00e+00 2224.00
IUUC-Cpo-022391 Cavia porcellus 84.76 0.00e+00 2074.00
IUUC-Csa-024170 Chlorocebus sabaeus 89.77 0.00e+00 1623.00
IUUC-Dre-027944 Danio rerio 72.05 0.00e+00 1779.00
IUUC-Dno-029440 Dasypus novemcinctus 87.57 0.00e+00 2120.00
IUUC-Dor-031001 Dipodomys ordii 87.44 0.00e+00 2201.00
IUUC-Eca-033809 Equus caballus 88.56 0.00e+00 2227.00
IUUC-Fca-036510 Felis catus 88.32 0.00e+00 2217.00
IUUC-Fal-037541 Ficedula albicollis 95.88 0.00e+00 2272.00
IUUC-Gmo-038630 Gadus morhua 78.49 0.00e+00 1372.00
IUUC-Gga-040142 Gallus gallus 98.12 0.00e+00 2417.00
IUUC-Ggo-045063 Gorilla gorilla 88.24 0.00e+00 2223.00
IUUC-Hsa-046428 Homo sapiens 88.16 0.00e+00 2219.00
IUUC-Itr-048245 Ictidomys tridecemlineatus 87.99 0.00e+00 2219.00
IUUC-Lch-049766 Latimeria chalumnae 80.74 0.00e+00 1977.00
IUUC-Loc-052285 Lepisosteus oculatus 77.60 0.00e+00 1935.00
IUUC-Laf-053365 Loxodonta africana 87.59 0.00e+00 2196.00
IUUC-Mcc-054871 Macaca mulatta 88.32 0.00e+00 2221.00
IUUC-Meu-056724 Macropus eugenii 83.92 0.00e+00 2052.00
IUUC-Mmr-061110 Microcebus murinus 88.08 0.00e+00 2212.00
IUUC-Mdo-062448 Monodelphis domestica 88.81 0.00e+00 2241.00
IUUC-Mmu-063565 Mus musculus 88.24 0.00e+00 2219.00
IUUC-Mpu-066683 Mustela putorius furo 88.33 0.00e+00 2222.00
IUUC-Mlu-067779 Myotis lucifugus 88.14 0.00e+00 2220.00
IUUC-Nfi-068248 Neosartorya fischeri 37.50 2.00e-10 62.00
IUUC-Nle-069219 Nomascus leucogenys 89.07 0.00e+00 1957.00
IUUC-Opr-070766 Ochotona princeps 84.26 0.00e+00 1311.00
IUUC-Ont-072524 Oreochromis niloticus 74.35 0.00e+00 1865.00
IUUC-Oan-073214 Ornithorhynchus anatinus 90.32 8.00e-45 172.00
IUUC-Ocu-074361 Oryctolagus cuniculus 86.57 0.00e+00 2170.00
IUUC-Ola-086820 Oryzias latipes 73.43 0.00e+00 1881.00
IUUC-Oga-088172 Otolemur garnettii 88.73 0.00e+00 2235.00
IUUC-Oar-090306 Ovis aries 85.63 0.00e+00 2143.00
IUUC-Ptr-090682 Pan troglodytes 88.24 0.00e+00 2222.00
IUUC-Pan-092835 Papio anubis 88.90 0.00e+00 1666.00
IUUC-Psi-093344 Pelodiscus sinensis 89.46 0.00e+00 2238.00
IUUC-Pfo-096984 Poecilia formosa 72.35 0.00e+00 1815.00
IUUC-Pab-097871 Pongo abelii 88.00 0.00e+00 2219.00
IUUC-Pop-099175 Populus trichocarpa 25.89 1.40e-02 33.50
IUUC-Pca-100772 Procavia capensis 81.71 0.00e+00 2015.00
IUUC-Pva-102790 Pteropus vampyrus 88.47 0.00e+00 2175.00
IUUC-Rno-105974 Rattus norvegicus 88.32 0.00e+00 2228.00
IUUC-Sar-112995 Sorex araneus 86.37 0.00e+00 2167.00
IUUC-Ssc-115360 Sus scrofa 87.99 0.00e+00 2220.00
IUUC-Tgu-116585 Taeniopygia guttata 93.71 0.00e+00 2247.00
IUUC-Tru-117742 Takifugu rubripes 74.19 0.00e+00 1891.00
IUUC-Tsy-119259 Tarsius syrichta 90.02 0.00e+00 793.00
IUUC-Tbe-127504 Tupaia belangeri 75.86 0.00e+00 1270.00
IUUC-Ttr-128650 Tursiops truncatus 89.46 0.00e+00 1096.00
IUUC-Xtr-132862 Xenopus tropicalis 77.90 0.00e+00 1893.00
Created Date 25-Jun-2017

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