iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048094

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01039173

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000005759.2	ENSSTOT00000005799.2	ENSSTOP00000005187.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.70e-42	139.3	637	669
UBD/Beta-Prp	1.50e-65	221.3	57	262

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt+++t+la+   +d++lvs+s+Dgt +vWD+
   Q: 637  GHTAKITSLAWsphHDGRLVSASYDGTAQVWDI 669
           8***********8766****************6 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcl 129
           + +l gh++ v+  +fs++     + +t+s+D+t+k+wd++t + v     h++++ +l++sp  +d +vsG++  ++ ++  + +   
   Q: 57   IGELVGHTERVSGFTFSHHPGqynLCATSSDDGTVKIWDVETKTVVTEHALHQHTISALHWSPrVKDLIVSGDEKGIVFCYWFNRNDSQ 145
           7899**************965677***************************************666**************855555555 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls...........fdsng............. 192
              l ++ +++ c++ +p   +l++ G +D++v + d+ k g+++++l+g h+d ++s++           +                 
   Q: 146  --HLFIEPRTIFCLTCSPHHeDLVAIGYKDGIVVIIDIsKKGEVIHRLRG-HDDEIHSIAwcplpgedclsI---Nqeenseepeipng 228
           ..4899999999999999999*****************999********9.*********777666666541...04567788999999 PP
   S: 193  ...........kelvsgsldgtvklwdlqtgecv 215
                       +l++gs+d+t+++w++++g+ v
   Q: 229  kliaqtpvtkgCYLATGSKDQTIRIWSCSRGRGV 262
           99999999999******************99765 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MGQEPRTLPP SPNWYCTRCS DAVPGGLFGF AARTSVFLVR VGPGAGTTPG TPAFRVIGEL 60
VGHTERVSGF TFSHHPGQYN LCATSSDDGT VKIWDVETKT VVTEHALHQH TISALHWSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGAGCTGC GAAAGATCCA TCCTTGTACC TGCTTCCTTC TGCCTCGGCT GCCGGTGATT 60
ATGGGGCAGG AACCGCGGAC GCTGCCGCCC TCTCCTAACT GGTACTGCAC CCGCTGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	90.42	0.00e+00	2325.00
IUUC-Apl-003586	Anas platyrhynchos	65.99	0.00e+00	1479.00
IUUC-Aca-004956	Anolis carolinensis	66.62	0.00e+00	1734.00
IUUC-Ame-010753	Astyanax mexicanus	62.38	0.00e+00	994.00
IUUC-Bta-012315	Bos taurus	89.29	0.00e+00	2326.00
IUUC-Cja-019334	Callithrix jacchus	90.80	0.00e+00	2404.00
IUUC-Cfa-021254	Canis familiaris	90.18	0.00e+00	2381.00
IUUC-Cpo-021984	Cavia porcellus	86.71	0.00e+00	2162.00
IUUC-Csa-023650	Chlorocebus sabaeus	90.07	0.00e+00	2361.00
IUUC-Cho-024860	Choloepus hoffmanni	83.90	0.00e+00	2118.00
IUUC-Cin-025778	Ciona intestinalis	41.59	2.00e-159	556.00
IUUC-Csv-026313	Ciona savignyi	41.01	1.00e-164	573.00
IUUC-Dre-028096	Danio rerio	55.00	0.00e+00	1391.00
IUUC-Dno-029799	Dasypus novemcinctus	88.46	0.00e+00	2246.00
IUUC-Dor-030885	Dipodomys ordii	74.36	0.00e+00	1093.00
IUUC-Ete-032918	Echinops telfairi	83.28	0.00e+00	2140.00
IUUC-Eca-034144	Equus caballus	89.39	0.00e+00	2264.00
IUUC-Eeu-034843	Erinaceus europaeus	81.73	0.00e+00	1556.00
IUUC-Fca-035948	Felis catus	89.67	0.00e+00	2313.00
IUUC-Fal-037303	Ficedula albicollis	65.36	0.00e+00	1687.00
IUUC-Gmo-039591	Gadus morhua	52.88	0.00e+00	839.00
IUUC-Gga-040570	Gallus gallus	67.58	0.00e+00	1512.00
IUUC-Gac-042646	Gasterosteus aculeatus	51.38	0.00e+00	1317.00
IUUC-Ggo-045605	Gorilla gorilla	82.25	0.00e+00	1858.00
IUUC-Hsa-046122	Homo sapiens	91.86	0.00e+00	2367.00
IUUC-Lch-050489	Latimeria chalumnae	56.52	0.00e+00	628.00
IUUC-Loc-052259	Lepisosteus oculatus	60.66	0.00e+00	969.00
IUUC-Laf-053338	Loxodonta africana	89.88	0.00e+00	2323.00
IUUC-Mcc-055442	Macaca mulatta	90.83	0.00e+00	2363.00
IUUC-Meu-056245	Macropus eugenii	82.96	0.00e+00	868.00
IUUC-Mga-060202	Meleagris gallopavo	66.75	0.00e+00	1575.00
IUUC-Mmr-061730	Microcebus murinus	89.27	0.00e+00	2306.00
IUUC-Mdo-062880	Monodelphis domestica	77.89	0.00e+00	1994.00
IUUC-Mmu-063930	Mus musculus	87.02	0.00e+00	2133.00
IUUC-Mpu-066605	Mustela putorius furo	89.43	0.00e+00	2333.00
IUUC-Mlu-067765	Myotis lucifugus	89.53	0.00e+00	2351.00
IUUC-Nle-069183	Nomascus leucogenys	91.56	0.00e+00	2338.00
IUUC-Opr-070659	Ochotona princeps	80.56	0.00e+00	934.00
IUUC-Ont-072356	Oreochromis niloticus	61.90	0.00e+00	1008.00
IUUC-Oan-073056	Ornithorhynchus anatinus	75.82	0.00e+00	1825.00
IUUC-Ocu-073881	Oryctolagus cuniculus	90.11	0.00e+00	2350.00
IUUC-Ola-087120	Oryzias latipes	57.49	1.00e-67	248.00
IUUC-Olu-087648	Ostreococcus lucimarinus	24.71	7.00e-29	122.00
IUUC-Oga-088343	Otolemur garnettii	90.25	0.00e+00	2341.00
IUUC-Oar-089257	Ovis aries	89.66	0.00e+00	2343.00
IUUC-Ptr-090497	Pan troglodytes	91.56	0.00e+00	2336.00
IUUC-Pan-092638	Papio anubis	90.68	0.00e+00	2360.00
IUUC-Psi-093096	Pelodiscus sinensis	69.36	0.00e+00	1486.00
IUUC-Pma-094571	Petromyzon marinus	43.38	2.00e-83	302.00
IUUC-Pfo-096348	Poecilia formosa	61.87	0.00e+00	980.00
IUUC-Pab-098153	Pongo abelii	91.63	0.00e+00	2398.00
IUUC-Pca-100957	Procavia capensis	83.04	0.00e+00	2186.00
IUUC-Pva-102439	Pteropus vampyrus	90.80	0.00e+00	2371.00
IUUC-Rno-105891	Rattus norvegicus	86.71	0.00e+00	2130.00
IUUC-Sha-107181	Sarcophilus harrisii	78.92	0.00e+00	1925.00
IUUC-Ssc-115413	Sus scrofa	88.98	0.00e+00	2343.00
IUUC-Tgu-117082	Taeniopygia guttata	66.07	0.00e+00	1669.00
IUUC-Tru-118491	Takifugu rubripes	59.41	0.00e+00	954.00
IUUC-Tsy-119629	Tarsius syrichta	94.12	1.00e-167	583.00
IUUC-Tni-120240	Tetraodon nigroviridis	59.73	0.00e+00	951.00
IUUC-Tbe-127673	Tupaia belangeri	80.29	0.00e+00	1943.00
IUUC-Ttr-128562	Tursiops truncatus	86.27	0.00e+00	2239.00
IUUC-Vpa-130596	Vicugna pacos	84.86	0.00e+00	1857.00
IUUC-Xtr-132469	Xenopus tropicalis	60.40	0.00e+00	1558.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence