iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060102

UUCD1 version

UUC-MeG-00443

Ensembl Protein ID

ENSMGAP00000010106.1

UniProt Accession

G1NBR7; G1NBR7_MELGA

Protein Name

Uncharacterized protein

Gene Name

CDC20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000009761.1	ENSMGAT00000010952.1	ENSMGAP00000010106.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	3.30e-144	479.5	175	483
E3 adaptor/Cullin RING/DCX/DWD	2.00e-26	90.7	310	342

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+++ldape+r+d+ylnL+dWss+n lavaL+++vylw++++g++++l ++ +++d+v+s+swi+eg++lavGt+++ev+++D++++k+
   Q: 175  PDRILDAPEIRNDYYLNLIDWSSQNFLAVALDNCVYLWNHSSGEIIQLLQIeNPDDYVSSLSWIKEGNYLAVGTRNAEVQLWDIQQQKR 263
           689************************************************8899********************************** PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse.....Pl 172
           +r++t+hs+rvg+LsWn+++lssGsr g+i+h+dvrv+e++++tl++h+qevCGlkw+ d+++LasGGnDn v++w + + +     P+
   Q: 264  LRSMTSHSSRVGSLSWNSYILSSGSRTGHIHHHDVRVAEHHVATLTGHTQEVCGLKWSLDGRYLASGGNDNLVNIWPSVQGDsgdftPV 352
           ****************************************************************************99988888999** PP
   S: 173  kkfkehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskva 261
           ++f++h++avka+aw+Pwq+++La+GGGt+Dr+i++wn+++g++l+++d++sqvcs+lws ++ke++s+hGfa+n++++wkyp+++kv+
   Q: 353  QTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGTCLSAVDAHSQVCSILWSTTYKEFISGHGFAQNQLVIWKYPTMAKVT 441
           ***************************************************************************************** PP
   S: 262  elkgheaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           el+gh+aRvl+l++spdg ++++aa+Detlr+w++f++++ k
   Q: 442  ELRGHTARVLNLTMSPDGVTVASAAADETLRLWRCFEMDPIK 483
           *************************************98765 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHt +v++l++  d ++l+sG++D+ + +W   
   Q: 310  GHTQEVCGLKWsLDgRYLASGGNDNLVNIWPSV 342
           8***********666***************655 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MAHFVFEADL HGLLKLDTPI PNAPPARWQR KAKESAGPSP AASMSPMKPA NRSYSGSKTP 60
SKTPGKSGSK VQSTPTKAGG DRYIPNRSAM QMEMANFLLT KENDPAENSP TKKEQQKSWA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGGCTGA GCGGGGACGT GGAGGTGAGA GGGGCCGGCG GCGGCTGGGC TCCGGGCCGG 60
AGGGTGTTGA GGTCCGAAGG GGGGAGGCCG TGGAGAAGGG TGGTCGCCGT GGAGAAGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033187--CDC20
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0007064--P:mitotic sister chromatid cohesion
GO:0090307--P:mitotic spindle assembly
GO:0090129--P:positive regulation of synapse maturation
GO:0031915--P:positive regulation of synaptic plasticity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000974	Aegilops tauschii	45.89	3.00e-109	388.00
IUUC-Aml-001545	Ailuropoda melanoleuca	80.36	0.00e+00	809.00
IUUC-Atr-003103	Amborella trichopoda	46.90	2.00e-109	389.00
IUUC-Apl-003255	Anas platyrhynchos	92.48	0.00e+00	847.00
IUUC-Aca-004920	Anolis carolinensis	80.12	0.00e+00	808.00
IUUC-Aly-006253	Arabidopsis lyrata	47.92	3.00e-110	391.00
IUUC-Ath-006795	Arabidopsis thaliana	47.58	3.00e-111	394.00
IUUC-Ago-007784	Ashbya gossypii	48.72	7.00e-87	314.00
IUUC-Ate-010479	Aspergillus terreus	47.31	3.00e-89	322.00
IUUC-Ame-010850	Astyanax mexicanus	61.89	3.00e-92	330.00
IUUC-Bgr-012059	Blumeria graminis	48.06	5.00e-93	334.00
IUUC-Bta-012625	Bos taurus	80.36	0.00e+00	811.00
IUUC-Bci-013607	Botrytis cinerea	48.13	2.00e-96	346.00
IUUC-Bdi-014344	Brachypodium distachyon	47.85	2.00e-109	389.00
IUUC-Bol-015368	Brassica oleracea	47.02	2.00e-108	387.00
IUUC-Bra-016738	Brassica rapa	47.82	1.00e-107	383.00
IUUC-Cja-019132	Callithrix jacchus	81.39	0.00e+00	818.00
IUUC-Cfa-020780	Canis familiaris	79.76	0.00e+00	806.00
IUUC-Cpo-022223	Cavia porcellus	80.99	0.00e+00	763.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	49.77	4.00e-116	410.00
IUUC-Csa-023666	Chlorocebus sabaeus	80.99	0.00e+00	813.00
IUUC-Cho-024920	Choloepus hoffmanni	78.40	1.00e-131	462.00
IUUC-Cin-025675	Ciona intestinalis	49.50	7.00e-131	460.00
IUUC-Csv-026019	Ciona savignyi	50.28	2.00e-126	446.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	41.36	8.00e-96	343.00
IUUC-Cme-027234	Cyanidioschyzon merolae	51.63	2.00e-105	375.00
IUUC-Dre-028026	Danio rerio	60.32	0.00e+00	630.00
IUUC-Dno-028865	Dasypus novemcinctus	80.83	0.00e+00	804.00
IUUC-Dor-030958	Dipodomys ordii	80.79	0.00e+00	803.00
IUUC-Dse-031391	Dothistroma septosporum	48.00	3.00e-97	348.00
IUUC-Dme-031905	Drosophila melanogaster	50.47	2.00e-146	511.00
IUUC-Ete-032387	Echinops telfairi	77.03	0.00e+00	784.00
IUUC-Eca-033522	Equus caballus	73.61	0.00e+00	730.00
IUUC-Eeu-035059	Erinaceus europaeus	73.32	0.00e+00	701.00
IUUC-Fca-036346	Felis catus	81.43	0.00e+00	734.00
IUUC-Fal-037558	Ficedula albicollis	89.66	0.00e+00	875.00
IUUC-Fox-037850	Fusarium oxysporum	45.33	8.00e-94	337.00
IUUC-Fso-038375	Fusarium solani	40.70	3.00e-95	342.00
IUUC-Gmo-039284	Gadus morhua	62.97	0.00e+00	631.00
IUUC-Ggr-039864	Gaeumannomyces graminis	47.40	1.00e-94	340.00
IUUC-Gga-040790	Gallus gallus	96.06	0.00e+00	966.00
IUUC-Gac-041431	Gasterosteus aculeatus	61.78	3.00e-179	620.00
IUUC-Gma-043489	Glycine max	46.80	2.00e-110	391.00
IUUC-Ggo-045052	Gorilla gorilla	80.99	0.00e+00	813.00
IUUC-Hsa-046305	Homo sapiens	80.99	0.00e+00	813.00
IUUC-Hvu-047565	Hordeum vulgare	46.12	5.00e-109	387.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	81.39	0.00e+00	768.00
IUUC-Lch-050174	Latimeria chalumnae	62.30	1.00e-173	602.00
IUUC-Lpe-050954	Leersia perrieri	47.92	5.00e-101	360.00
IUUC-Loc-052638	Lepisosteus oculatus	64.37	0.00e+00	638.00
IUUC-Lma-052998	Leptosphaeria maculans	40.90	8.00e-99	353.00
IUUC-Laf-053742	Loxodonta africana	81.39	0.00e+00	815.00
IUUC-Mcc-054948	Macaca mulatta	80.99	0.00e+00	813.00
IUUC-Meu-056013	Macropus eugenii	75.87	4.00e-128	451.00
IUUC-Mor-057277	Magnaporthe oryzae	49.51	5.00e-92	331.00
IUUC-Mpo-057624	Magnaporthe poae	49.51	1.00e-92	333.00
IUUC-Mtr-057725	Medicago truncatula	46.17	1.00e-102	366.00
IUUC-Mmr-061615	Microcebus murinus	80.70	0.00e+00	807.00
IUUC-Mdo-061982	Monodelphis domestica	79.64	0.00e+00	701.00
IUUC-Mmu-063864	Mus musculus	80.16	0.00e+00	805.00
IUUC-Mac-064861	Musa acuminata	47.57	3.00e-108	385.00
IUUC-Mpu-066502	Mustela putorius furo	79.96	0.00e+00	803.00
IUUC-Mlu-067277	Myotis lucifugus	75.25	0.00e+00	773.00
IUUC-Nle-070149	Nomascus leucogenys	80.99	0.00e+00	808.00
IUUC-Opr-070778	Ochotona princeps	78.63	3.00e-164	571.00
IUUC-Ont-071660	Oreochromis niloticus	64.62	3.00e-179	621.00
IUUC-Oan-073677	Ornithorhynchus anatinus	69.63	0.00e+00	670.00
IUUC-Ocu-073797	Oryctolagus cuniculus	80.88	0.00e+00	811.00
IUUC-Oba-075514	Oryza barthii	48.17	3.00e-101	361.00
IUUC-Obr-076018	Oryza brachyantha	46.02	4.00e-109	387.00
IUUC-Ogl-077254	Oryza glaberrima	48.17	2.00e-101	362.00
IUUC-Ogu-078521	Oryza glumaepatula	48.65	2.00e-107	383.00
IUUC-Oin-080094	Oryza indica	48.17	2.00e-101	362.00
IUUC-Olo-080449	Oryza longistaminata	48.17	1.00e-101	362.00
IUUC-Ome-081186	Oryza meridionalis	48.29	2.00e-108	386.00
IUUC-Oni-082243	Oryza nivara	48.17	2.00e-101	362.00
IUUC-Opu-083901	Oryza punctata	46.24	8.00e-108	383.00
IUUC-Oru-084357	Oryza rufipogon	48.17	4.00e-101	361.00
IUUC-Osa-086094	Oryza sativa	48.17	3.00e-101	361.00
IUUC-Ola-086907	Oryzias latipes	63.31	3.00e-166	577.00
IUUC-Olu-087647	Ostreococcus lucimarinus	47.01	2.00e-119	422.00
IUUC-Oga-088184	Otolemur garnettii	80.24	0.00e+00	801.00
IUUC-Oar-090023	Ovis aries	77.91	0.00e+00	734.00
IUUC-Ptr-090935	Pan troglodytes	80.17	0.00e+00	754.00
IUUC-Pan-091845	Papio anubis	80.99	0.00e+00	813.00
IUUC-Psi-093188	Pelodiscus sinensis	87.33	0.00e+00	915.00
IUUC-Pma-094187	Petromyzon marinus	50.20	8.00e-139	486.00
IUUC-Pno-094809	Phaeosphaeria nodorum	41.11	2.00e-99	355.00
IUUC-Ppa-095687	Physcomitrella patens	48.71	2.00e-116	412.00
IUUC-Pfo-097429	Poecilia formosa	59.41	1.00e-160	558.00
IUUC-Pab-098603	Pongo abelii	81.19	0.00e+00	814.00
IUUC-Pop-098890	Populus trichocarpa	46.70	1.00e-104	373.00
IUUC-Pca-101062	Procavia capensis	80.59	0.00e+00	800.00
IUUC-Ppe-101865	Prunus persica	47.27	3.00e-99	354.00
IUUC-Pva-102925	Pteropus vampyrus	80.79	0.00e+00	832.00
IUUC-Pte-104142	Pyrenophora teres	40.22	1.00e-96	347.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	47.13	2.00e-96	346.00
IUUC-Rno-106005	Rattus norvegicus	80.16	0.00e+00	804.00
IUUC-Sha-107472	Sarcophilus harrisii	79.17	0.00e+00	807.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	42.79	9.00e-93	333.00
IUUC-Spo-108075	Schizosaccharomyces pombe	43.49	5.00e-94	337.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	47.55	4.00e-95	341.00
IUUC-Smo-108922	Selaginella moellendorffii	46.82	1.00e-119	422.00
IUUC-Sit-110732	Setaria italica	46.37	5.00e-109	387.00
IUUC-Sly-111025	Solanum lycopersicum	45.69	9.00e-99	353.00
IUUC-Stu-112676	Solanum tuberosum	45.79	2.00e-100	358.00
IUUC-Sar-113092	Sorex araneus	76.83	0.00e+00	752.00
IUUC-Sbi-114558	Sorghum bicolor	46.17	3.00e-109	388.00
IUUC-Ssc-115710	Sus scrofa	80.95	0.00e+00	814.00
IUUC-Tgu-117100	Taeniopygia guttata	88.87	0.00e+00	872.00
IUUC-Tru-118184	Takifugu rubripes	60.05	5.00e-143	500.00
IUUC-Tsy-118892	Tarsius syrichta	78.32	1.00e-133	468.00
IUUC-Tni-120474	Tetraodon nigroviridis	63.04	3.00e-168	584.00
IUUC-Tca-120949	Theobroma cacao	46.07	3.00e-109	388.00
IUUC-Tre-122211	Trichoderma reesei	38.75	7.00e-94	337.00
IUUC-Tvi-122531	Trichoderma virens	39.04	1.00e-93	336.00
IUUC-Tae-123765	Triticum aestivum	45.89	2.00e-109	389.00
IUUC-Tur-126018	Triticum urartu	46.12	4.00e-103	367.00
IUUC-Tbe-127384	Tupaia belangeri	84.90	2.00e-154	538.00
IUUC-Ttr-128511	Tursiops truncatus	80.56	0.00e+00	810.00
IUUC-Vda-129993	Verticillium dahliae	40.47	7.00e-96	344.00
IUUC-Vvi-131245	Vitis vinifera	48.28	2.00e-97	348.00
IUUC-Xtr-131993	Xenopus tropicalis	79.49	0.00e+00	808.00
IUUC-Xma-133332	Xiphophorus maculatus	64.03	3.00e-178	617.00
IUUC-Zma-135135	Zea mays	47.09	4.00e-106	377.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence